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Volumn 111, Issue 3, 2013, Pages 539-548

'VASPFix' for measurement of VASP phosphorylation in platelets and for monitoring effects of P2Y12 antagonists

Author keywords

Cyclic nucleotides; Cytometric bead assay; Platelets; VASP phosphorylation

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; ILOPROST; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 84897088268     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-07-0581     Document Type: Article
Times cited : (10)

References (30)
  • 2
    • 0025910262 scopus 로고
    • Comparison of vasodilatory prostaglandins with respect to cAMP-mediated phosphorylation of a target substrate in intact human platelets
    • Nolte C, Eigenthaler M, Schanzenbacher P et al. Comparison of vasodilatory prostaglandins with respect to cAMP-mediated phosphorylation of a target substrate in intact human platelets. Biochem Pharmacol 1991; 42: 253-262.
    • (1991) Biochem Pharmacol , vol.42 , pp. 253-262
    • Nolte, C.1    Eigenthaler, M.2    Schanzenbacher, P.3
  • 3
    • 0032800250 scopus 로고    scopus 로고
    • Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signalling by the antiplatelet drug clopidogrel
    • Geiger J, Brich J, Honig-Liedl P et al. Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signalling by the antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol 1999; 19: 2007-2011.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2007-2011
    • Geiger, J.1    Brich, J.2    Honig-Liedl, P.3
  • 4
    • 0347416957 scopus 로고    scopus 로고
    • Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets
    • Sudo T, Ito H, Kimura Y. Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets. Platelets 2003; 14: 381-390.
    • (2003) Platelets , vol.14 , pp. 381-390
    • Sudo, T.1    Ito, H.2    Kimura, Y.3
  • 5
    • 55449087392 scopus 로고    scopus 로고
    • Evaluation of the antiplatelet effects of cilostazol, a phosphodiesterase 3 inhibitor, by VASP phosphorylation and platelet aggregation
    • Yamamoto H, Takahashi K, Watanabe H et al. Evaluation of the antiplatelet effects of cilostazol, a phosphodiesterase 3 inhibitor, by VASP phosphorylation and platelet aggregation. Circ J 2008; 72: 1844-1851.
    • (2008) Circ J , vol.72 , pp. 1844-1851
    • Yamamoto, H.1    Takahashi, K.2    Watanabe, H.3
  • 6
    • 79751494990 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein (VASP) phosphorylation assay for platelet response to cilostazol
    • Yamanouchi J, Hato T, Niiya T et al. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation assay for platelet response to cilostazol. Platelets 2010; 22: 135-142.
    • (2010) Platelets , vol.22 , pp. 135-142
    • Yamanouchi, J.1    Hato, T.2    Niiya, T.3
  • 7
    • 0037335810 scopus 로고    scopus 로고
    • Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: In vitro and in vivo/ex vivo studies
    • Aktas B, Utz A, Hoenig-Liedl P et al. Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: In vitro and in vivo/ex vivo studies. Stroke 2003; 34: 764-769.
    • (2003) Stroke , vol.34 , pp. 764-769
    • Aktas, B.1    Utz, A.2    Hoenig-Liedl, P.3
  • 8
    • 37349065481 scopus 로고    scopus 로고
    • Redox state of dipyridamole is a critical determinant for its beneficial antioxidant and antiinflammatory effects
    • Chakrabarti S, Blair P, Wu C et al. Redox state of dipyridamole is a critical determinant for its beneficial antioxidant and antiinflammatory effects. J Cardiovasc Pharmacol 2007; 50: 449-457.
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 449-457
    • Chakrabarti, S.1    Blair, P.2    Wu, C.3
  • 9
    • 0032873146 scopus 로고    scopus 로고
    • 1999 Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets-Definition and detection of ticlopidine/ clopidogrel effects
    • Schwarz UR, Geiger J, Walter U et al. 1999 Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets-Definition and detection of ticlopidine/ clopidogrel effects. Thromb Haemost 1999; 82: 1145-1152.
    • (1999) Thromb Haemost , vol.82 , pp. 1145-1152
    • Schwarz, U.R.1    Geiger, J.2    Walter, U.3
  • 10
    • 0038354521 scopus 로고    scopus 로고
    • Resistance to Thienopyridines: Clinical Detection of Coronary Stent Thrombosis by Monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation
    • Barragan P, Bouvier J-L, Roquebert P-O et al. Resistance to Thienopyridines: Clinical Detection of Coronary Stent Thrombosis by Monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation. Catheter Cardiovasc Interv 2003; 59: 295-302.
    • (2003) Catheter Cardiovasc Interv , vol.59 , pp. 295-302
    • Barragan, P.1    Bouvier, J.-L.2    Roquebert, P.-O.3
  • 11
    • 15944383861 scopus 로고    scopus 로고
    • Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases
    • Aleil B, Ravanat C, Cazenave JP et al. Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases. J Thromb Haemost 2005; 3: 85-92.
    • (2005) J Thromb Haemost , vol.3 , pp. 85-92
    • Aleil, B.1    Ravanat, C.2    Cazenave, J.P.3
  • 12
    • 36949000480 scopus 로고    scopus 로고
    • The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis
    • Blindt R, Stellbrink K, de Taeye A et al. The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis. Thromb Haemost 2007; 98: 1329-1334.
    • (2007) Thromb Haemost , vol.98 , pp. 1329-1334
    • Blindt, R.1    Stellbrink, K.2    de Taeye, A.3
  • 13
    • 34447636769 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events
    • Bonello L, Paganelli F, Arpin-Bornet M et al. Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events. J Thromb Haemost 2007; 5: 1630-1636.
    • (2007) J Thromb Haemost , vol.5 , pp. 1630-1636
    • Bonello, L.1    Paganelli, F.2    Arpin-Bornet, M.3
  • 14
    • 54949155995 scopus 로고    scopus 로고
    • ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay
    • Schäfer A, Weinberger S, Flierl U et al. ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay. Thromb Haemost 2008; 100: 618-625.
    • (2008) Thromb Haemost , vol.100 , pp. 618-625
    • Schäfer, A.1    Weinberger, S.2    Flierl, U.3
  • 15
    • 77949297362 scopus 로고    scopus 로고
    • Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel
    • Bouman HJ, Parlak E, van Werkum JW et al. Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel. J Thromb Haemost 2010; 8: 482-488.
    • (2010) J Thromb Haemost , vol.8 , pp. 482-488
    • Bouman, H.J.1    Parlak, E.2    van Werkum, J.W.3
  • 16
    • 41249096421 scopus 로고    scopus 로고
    • Will measuring vasodilator-stimulated phosphoprotein phosphorylation help us optimize the loading dose of clopidogrel?
    • Kleiman NS. Will measuring vasodilator-stimulated phosphoprotein phosphorylation help us optimize the loading dose of clopidogrel? J Am Coll Cardiol 2008; 51: 1412-1414.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1412-1414
    • Kleiman, N.S.1
  • 17
    • 84886305756 scopus 로고    scopus 로고
    • A randomized trial of platelet reactivity monitoring-adjusted clopidogrel therapy versus prasugrel therapy to reduce high on-treatment platelet reactivity
    • Epub ahead of print
    • Bonello L, Laine M, Baumstarck K et al. A randomized trial of platelet reactivity monitoring-adjusted clopidogrel therapy versus prasugrel therapy to reduce high on-treatment platelet reactivity. Int J Cardiol 2013; Epub ahead of print.
    • (2013) Int J Cardiol
    • Bonello, L.1    Laine, M.2    Baumstarck, K.3
  • 18
    • 77955453896 scopus 로고    scopus 로고
    • Validation of a novel ELISA-based VASP whole blood assay to measure P2Y12-ADP receptor activity
    • Barragan P, Paganelli F, Camoin-Jau L et al. Validation of a novel ELISA-based VASP whole blood assay to measure P2Y12-ADP receptor activity. Thromb Haemost 2010; 104: 410-411.
    • (2010) Thromb Haemost , vol.104 , pp. 410-411
    • Barragan, P.1    Paganelli, F.2    Camoin-Jau, L.3
  • 19
    • 77957221052 scopus 로고    scopus 로고
    • A protein phosphorylation-based assay for screening and monitoring of drugs modulating cyclic nucleotide pathways
    • Geiger J, Brandmann T, Hubertus K et al. A protein phosphorylation-based assay for screening and monitoring of drugs modulating cyclic nucleotide pathways. Anal Biochem 2010; 407: 261-269.
    • (2010) Anal Biochem , vol.407 , pp. 261-269
    • Geiger, J.1    Brandmann, T.2    Hubertus, K.3
  • 20
    • 84856679890 scopus 로고    scopus 로고
    • Comparison of a new ELISA assay with the flow cytometric assay for platelet vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation in whole blood to assess P2Y(12) inhibition
    • Jakubowski JA, Bourguet N, Boulay-Moine D et al. Comparison of a new ELISA assay with the flow cytometric assay for platelet vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation in whole blood to assess P2Y(12) inhibition. Thromb Haemost 2012; 107: 388-395.
    • (2012) Thromb Haemost , vol.107 , pp. 388-395
    • Jakubowski, J.A.1    Bourguet, N.2    Boulay-Moine, D.3
  • 21
    • 84886992718 scopus 로고    scopus 로고
    • Identification of poor response to P2Y12 inhibitors in ACS patients with a new ELISA-based vasodilator-associated stimu-lated phosphoprotein (VASP) phosphorylation assay
    • Abtan J, Silvain J, Kerneis M et al. Identification of poor response to P2Y12 inhibitors in ACS patients with a new ELISA-based vasodilator-associated stimu-lated phosphoprotein (VASP) phosphorylation assay. Thromb Haemost 2013; 110: 1055-1064.
    • (2013) Thromb Haemost , vol.110 , pp. 1055-1064
    • Abtan, J.1    Silvain, J.2    Kerneis, M.3
  • 22
    • 84897098241 scopus 로고    scopus 로고
    • Comparison of a new ELISA-based with the flow cytometric assay for vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation to assess P2Y12-inhibition after ticagrelor intake
    • Epub ahead of print
    • Hobl EL, Jilma B, Derhaschnig U et al. Comparison of a new ELISA-based with the flow cytometric assay for vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation to assess P2Y12-inhibition after ticagrelor intake. Cytometry B Clin Cytom 2013; Epub ahead of print.
    • (2013) Cytometry B Clin Cytom
    • Hobl, E.L.1    Jilma, B.2    Derhaschnig, U.3
  • 23
    • 0028303913 scopus 로고
    • cAMP-dependent and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in-vitro and in intact human platelets
    • Butt E, Abel K, Krieger M et al. cAMP-dependent and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in-vitro and in intact human platelets. J Biol Chem 1994; 269: 14509-14517.
    • (1994) J Biol Chem , vol.269 , pp. 14509-14517
    • Butt, E.1    Abel, K.2    Krieger, M.3
  • 24
    • 79551533370 scopus 로고    scopus 로고
    • PGE(1) and PGE(2) modify platelet function through different prostanoid receptors
    • Iyu D, Juttner M, Glenn JR et al. PGE(1) and PGE(2) modify platelet function through different prostanoid receptors. Prostagland Lipid Med 2011; 94: 9-16.
    • (2011) Prostagland Lipid Med , vol.94 , pp. 9-16
    • Iyu, D.1    Juttner, M.2    Glenn, J.R.3
  • 25
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. New Engl J Med 2007; 357: 2001-2015.
    • (2007) New Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 26
    • 34250714831 scopus 로고    scopus 로고
    • The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
    • Sugidachi A, Ogawa T, Kurihara A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost 2007; 5: 1545-1551.
    • (2007) J Thromb Haemost , vol.5 , pp. 1545-1551
    • Sugidachi, A.1    Ogawa, T.2    Kurihara, A.3
  • 27
    • 0036379817 scopus 로고    scopus 로고
    • Individual variations of platelet inhibition after loading doses of clopidogrel
    • Jaremo P, Lindahl TL, Fransson SG et al. Individual variations of platelet inhibition after loading doses of clopidogrel. J Intern Med 2002; 252: 233-238.
    • (2002) J Intern Med , vol.252 , pp. 233-238
    • Jaremo, P.1    Lindahl, T.L.2    Fransson, S.G.3
  • 28
    • 77953159705 scopus 로고    scopus 로고
    • Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function
    • Judge HM, Buckland RJ, Sugidachi A et al. Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function. Thromb Haemost 2010; 103: 1210-1217.
    • (2010) Thromb Haemost , vol.103 , pp. 1210-1217
    • Judge, H.M.1    Buckland, R.J.2    Sugidachi, A.3
  • 29
    • 79951848755 scopus 로고    scopus 로고
    • The platelet P2Y12 receptor for adenosine diphosphate: Congenital and drug-induced defects
    • Cattaneo M. The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects. Blood 2011; 117: 2102-2112.
    • (2011) Blood , vol.117 , pp. 2102-2112
    • Cattaneo, M.1
  • 30
    • 78649371969 scopus 로고    scopus 로고
    • Usefulness of a flow cytometric analysis of intraplatelet vasodilator-stimulated phosphoprotein phosphorylation for the detection of patients with genetic defects of the platelet P2Y12 receptor for ADP
    • Zighetti ML, Carpani G, Sinigaglia E et al. Usefulness of a flow cytometric analysis of intraplatelet vasodilator-stimulated phosphoprotein phosphorylation for the detection of patients with genetic defects of the platelet P2Y12 receptor for ADP. J Thromb Haemost 2010; 8: 2332-2334.
    • (2010) J Thromb Haemost , vol.8 , pp. 2332-2334
    • Zighetti, M.L.1    Carpani, G.2    Sinigaglia, E.3


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