Postoperative pain and long-term functional outcome after administration of gabapentin and pregabalin in patients undergoing spinal surgery

Spine

Volumn 39, Issue 6, 2014, Pages

  Khurana, Gurjeet ^a   Jindal, Parul ^a   Sharma, Jagdish P ^a   Bansal, Krishan K ^a  

^a HIMALAYAN INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Functional outcome; Gabapentin; Lumbar discectomy; Oswestry disability index score; Postoperative pain; Pregabalin; Prolo score; Visual analogue scale

Indexed keywords

GABAPENTIN; PLACEBO; PREGABALIN;

ADULT; AGED; ARTICLE; ATAXIA; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; FUNCTIONAL STATUS; GENERAL ANESTHESIA; HUMAN; INTERVERTEBRAL DISKECTOMY; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OSWESTRY DISABILITY INDEX; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROLO FUNCTIONAL AND ECONOMIC SCORE; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SOMNOLENCE; SPINE SURGERY; VISUAL ANALOG SCALE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AMINES; ANALGESICS; CYCLOHEXANECARBOXYLIC ACIDS; DISABILITY EVALUATION; DOUBLE-BLIND METHOD; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; INDIA; MALE; MIDDLE AGED; ORTHOPEDIC PROCEDURES; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROSPECTIVE STUDIES; QUALITY OF LIFE; QUESTIONNAIRES; RECOVERY OF FUNCTION; SPINE; TIME FACTORS; YOUNG ADULT;

EID: 84897077864     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0000000000000185     Document Type: Article

References (20)

1. Nasir M , Latif K , Ahmad MJ . Pre-emptive pain control: Comparison of ketorolac and diclofenac sodium . Prof Med J 2007 ; 14 : 591-7.
2. Rose MA , Kam PC . Gabapentin: Pharmacology and its use in pain management . Anaesthesia 2002 ; 57 : 451-62.
3. Ben-Menachem E . Pregabalin pharmacology and its relevance to clinical practice . Epilepsia 2004 ; 45 : 13-8.
4. Guay DR . Pregabalin in neuropathic pain: A more pharmaceutically elegant gabapentin ? Am J Geriatr Pharmacother 2005 ; 3 : 274-87.
5. Tiipana EM , Hamsunen K , Kontinen VK , et al. Do surgical patients benefi t from perioperative gabapentin/pregabalin? A systematic review of effi cacy and safety . Anesth Analg 2007 ; 104 : 1545-6.
6. Fairbank JC , Pynsent PB . The Oswestry Disability Index . Spine 2000 ; 25 : 2940-52.
7. Vitzthum HE , Dalitz K . Analysis of five specifi c scores for cervical spondylogenic myelopathy . Eur Spine J 2007 ; 16 : 2096-103.
8. Iohom G , Abdalla H , O'Brien J , et al. The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery . Anesth Analg 2006 ; 103 : 995-1000.
9. Fassoulaki A , Triga A , Melemeni A , et al. Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer . Anesth Analg 2005 ; 101 : 1427-32.
10. Gilron I , Orr E , Tu D , et al. A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy . Pain 2005 ; 113 : 191-200.
11. Turan A , White PF , Karamanlioglu B , et al. Gabapentin: An alternative to the cyclooxygenase-2 inhibitors for perioperative pain management . Anesth Analg 2006 ; 102 : 175-81.
12. Ittichaikulthol W , Virankabutra T , Kunopart M , et al. Effects of pregabalin on postoperative morphine consumption and pain after abdominal hysterectomy with/without salpingo-oophorectomy: A randomized, double-blind trial . J Med Assoc Thai 2009 ; 92 : 1318-23.
13. Wesche D , Bickbraden H . A pharmacokinetic comparison of pregabalin and gabapentin . Pain 2005 ; 6 : S29.
14. Ghai A , Gupta M , Hooda S , et al. A randomized controlled trial to compare pregabalin and gabapentin for postoperative pain in abdominal hysterectomy . SJA 2011 ; 5 : 252-6.
15. Gianesello L , Pavoni V , Barboni E , et al. Perioperative pregabalin for postoperative pain control and quality of life after major spinal surgery . J Neurosurg Anesthesiol 2012 ; 24 : 121-6.
16. Kim JC , Choi YS , Kim KN , et al. Effective dose of perioperative oral pregabalin as an adjunct to multimodal analgesic regimen in lumbar spinal fusion surgery . Spine 2011 ; 36 : 428-33.
17. Burke SM , Shorten GB . Perioperative pregabalin improves pain and functional outcome 3 months after lumbar discectomy . Anesth Analg 2010 ; 110 : 1180-5.
18. Woolf CJ , Chong MS . Preemptive analgesia treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993 ; 77 : 362-79.
19. Turan A , Karamanlioglu B , Memis D , et al. Analgesic effects of gabapentin after spinal surgery . Anesthesiology 2004 ; 100 : 935-8.
20. Wilder-Smith OH , Tassonyi E , Crul BJ , et al. Preoperative back pain is associated with diverse manifestations of central neuroplasticity . Pain 2002 ; 97 : 189-94.