Two nursing mothers treated with zonisamide: Should breast-feeding be avoided?

Journal of Obstetrics and Gynaecology Research

Volumn 40, Issue 1, 2014, Pages 275-278

  Ando, Hitoshi ^a   Matsubara, Shigeki ^a   Oi, Asako ^a   Usui, Rie ^a   Suzuki, Mitsuaki ^a   Fujimura, Akio ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Antiepileptic drug; Breast milk; Breast feeding; Relative infant dose; Zonisamide

Indexed keywords

ZONISAMIDE;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; BREAST FEEDING; BREAST MILK; CASE REPORT; COLOSTRUM; DELIVERY; DRUG BLOOD LEVEL; DRUG MILK LEVEL; DRUG SAFETY; EPILEPSY; FEMALE; HUMAN; LIMIT OF DETECTION;

ANTIEPILEPTIC DRUG; BREAST MILK; BREAST-FEEDING; RELATIVE INFANT DOSE; ZONISAMIDE;

ADULT; ANTICONVULSANTS; BIOLOGICAL AVAILABILITY; BREAST FEEDING; CHILD DEVELOPMENT; EPILEPSY; FEMALE; FETAL BLOOD; HUMANS; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; ISOXAZOLES; LACTATION; MALE; MILK, HUMAN;

EID: 84897072130     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/jog.12143     Document Type: Article

References (12)

1. Fortinguerra F, Clavenna A, Bonati M. Psychotropic drug use during breastfeeding: A review of the evidence. Pediatrics 2009; 124: e547-e556.
2. Hale TW. Medications and Mothers' Milk, 14th edn. Amarillo, TX: Hale Pub, 2010.
3. Frampton JE, Scott LJ. Zonisamide: A review of its use in the management of partial seizures in epilepsy. CNS Drugs 2005; 19: 347-367.
4. Kawada K, Itoh S, Kusaka T, Isobe K, Ishii M. Pharmacokinetics of zonisamide in perinatal period. Brain Dev 2002; 24: 95-97.
5. Shimoyama R, Ohkubo T, Sugawara K. Monitoring of zonisamide in human breast milk and maternal plasma by solidphase extraction HPLC method. Biomed Chromatogr 1999; 13: 370-372.
6. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am 2013; 60: 275-294.
7. Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation, 9th Edn. Philadelphia, PA: Lippincott Williams & Wilkins, 2011.
8. Hovinga CA, Pennell PB. Antiepileptic drug therapy in pregnancy II: Fetal and neonatal exposure. Int Rev Neurobiol 2008; 83: 241-258.
9. Kochak GM, Page JG, Buchanan RA, Peters R, Padgett CS. Steady-state pharmacokinetics of zonisamide, an antiepileptic agent for treatment of refractory complex partial seizures. J Clin Pharmacol 1998; 38: 166-171.
10. Section on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 2012; 129: e827-e841.
11. Bilenko N, Ghosh R, Levy A, Deckelbaum RJ, Fraser D. Partial breastfeeding protects Bedouin infants from infection and morbidity: Prospective cohort study. Asia Pac J Clin Nutr 2008; 17: 243-249.
12. Walker A. Breast milk as the gold standard for protective nutrients. J Pediatr 2010; 156: S3-S7.