Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles

Heart Rhythm

Volumn 11, Issue 4, 2014, Pages 697-706

  Maruyama, Mitsunori ^a,b   Ai, Tomohiko ^a   Chua, Su Kiat ^a   Park, Hyung Wook ^a   Lee, Young Soo ^a   Shen, Mark J ^a   Chang, Po Cheng ^a   Lin, Shien Fong ^a   Chen, Peng Sheng ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Afterdepolarization; ATP sensitive potassium channels; Electrical storm; Hypokalemia; Intracellular calcium; Ventricular fibrillation

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; APAMIN; CALCIUM ION; GLIBENCLAMIDE; ISOPRENALINE; NIFEDIPINE; POTASSIUM ION; CALCIUM;

ACTION POTENTIAL; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CONTROLLED STUDY; DEFIBRILLATION; DRUG EFFECT; ELECTRICAL STORM; EXTRACELLULAR POTASSIUM; EXTRASYSTOLE; HEART DEPOLARIZATION; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE FIBRILLATION; HYPOKALEMIA; LATE PHASE 3 EARLY AFTERDEPOLARIZATION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; QRS COMPLEX; RECURRENT DISEASE; SHOCK; T WAVE; ANIMAL; COMPLICATION; HEART VENTRICLE; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; PATHOPHYSIOLOGY; RABBIT; ACTION POTENTIAL DURATION; CHLORIDE CURRENT; CORONARY ARTERY BLOOD FLOW; EARLY AFTERDEPOLARIZATION; ELECTRIC SHOCK; HEART REPOLARIZATION; HEART VENTRICLE TACHYCARDIA; ISOLATED HEART;

ANIMALS; CALCIUM; HEART VENTRICLES; HYPOKALEMIA; IN VITRO TECHNIQUES; INFUSIONS, INTRAVENOUS; ISOPROTERENOL; RABBITS; RECURRENCE; VENTRICULAR FIBRILLATION;

EID: 84897037694     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.12.032     Document Type: Article

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