The impact of influenza vaccination on hospitalizations and mortality among frail older people

Journal of the American Medical Directors Association

Volumn 15, Issue 4, 2014, Pages 256-260

  Lee, Wei Ju ^a,b   Chen, Liang Kung ^a,b   Tang, Gau Jun ^a   Lan, Tzuo Yun ^a,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Death; Hospitalization; Influenza vaccination; Older adults

Indexed keywords

AGE; AGED; ARTICLE; CLINICAL EFFECTIVENESS; COHORT ANALYSIS; CONTROLLED STUDY; EXAMINATION; FEMALE; FOLLOW UP; FRAIL ELDERLY; GENDER; HOSPITALIZATION; HUMAN; INFLUENZA VACCINATION; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; MORTALITY; NATIONAL HEALTH INSURANCE; RETROSPECTIVE STUDY; RURAL AREA; SOCIAL STATUS; TAIWAN; VERY ELDERLY; EPIDEMIOLOGY; INFLUENZA, HUMAN; INSURANCE; PREVENTIVE HEALTH SERVICE; STATISTICS AND NUMERICAL DATA;

INFLUENZA VACCINE;

AGED; AGED, 80 AND OVER; FEMALE; FRAIL ELDERLY; HOSPITALIZATION; HUMANS; IMMUNIZATION PROGRAMS; INFLUENZA VACCINES; INFLUENZA, HUMAN; INSURANCE CLAIM REVIEW; MALE; RETROSPECTIVE STUDIES; TAIWAN;

EID: 84897023825     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2013.12.003     Document Type: Article

References (41)

1. Thompson W.W., Shay D.K., Weintraub E., et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003, 289:179-186.
2. Thompson W.W., Shay D.K., Weintraub E., et al. Influenza-associated hospitalizations in the United States. JAMA 2004, 292:1333-1340.
3. Estimates of deaths associated with seasonal influenza-United States, 1976-2007. MMWR Morb Mortal Wkly Rep 2010, 59:1057-1062. Centers for Disease Control and Prevention.
4. Davenport F.M. Current knowledge of influenza vaccine. JAMA 1962, 182:11-13.
5. Prevention and control of influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices (ACIP)-United States, 2012-13 influenza season. MMWR Morb Mortal Wkly Rep 2012, 61:613-618. Centers for Disease Control and Prevention.
6. Sahin E., DePinho R.A. Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature 2010, 464:520-528.
7. McElhaney J.E. Influenza vaccine responses in older adults. Ageing Res Rev 2011, 10:379-388.
8. Osterholm M.T., Kelley N.S., Sommer A., Belongia E.A. Efficacy and effectiveness of influenza vaccines: A systematic review and meta-analysis. Lancet Infect Dis 2012, 12:36-44.
9. Jackson M.L., Nelson J.C., Weiss N.S., et al. Influenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: A population-based, nested case-control study. Lancet 2008, 372:398-405.
10. Chan T.C., Hung I.F., Luk J.K., et al. Functional status of older nursing home residents can affect the efficacy of influenza vaccination. JGerontol A Biol Sci Med Sci 2013, 68:324-330.
11. Yao X., Hamilton R.G., Weng N.P., et al. Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults. Vaccine 2011, 29:5015-5021.
12. Fried L.P., Tangen C.M., Walston J., et al. Frailty in older adults: Evidence for a phenotype. JGerontol A Biol Sci Med Sci 2001, 56:M146-M156.
13. Karunananthan S., Wolfson C., Bergman H., et al. Amultidisciplinary systematic literature review on frailty: Overview of the methodology used by the Canadian Initiative on Frailty and Aging. BMC Med Res Methodol 2009, 9:68.
14. Hamaker M.E., Jonker J.M., de Rooij S.E., et al. Frailty screening methods for predicting outcome of a comprehensive geriatric assessment in elderly patients with cancer: A systematic review. Lancet Oncol 2012, 13:e437-e444.
15. Morley J.E., Vellas B., van Kan G.A., et al. Frailty consensus: A call to action. JAm Med Dir Assoc 2013, 14:392-397.
16. Searle S.D., Mitnitski A., Gahbauer E.A., et al. Astandard procedure for creating a frailty index. BMC Geriatr 2008, 8:24.
17. Xue Q.L. The frailty syndrome: Definition and natural history. Clin Geriatr Med 2011, 27:1-15.
18. Sternberg S.A., Bentur N., Abrams C., et al. Identifying frail older people using predictive modeling. Am J Manag Care 2012, 18:e392-e397.
19. Chang H.Y., Weiner J.P. An in-depth assessment of a diagnosis-based risk adjustment model based on national health insurance claims: the application of the Johns Hopkins Adjusted Clinical Group case-mix system in Taiwan. BMC Med 2010, 8:7.
20. Lee W.C. Quantifying morbidities by Adjusted Clinical Group system for a Taiwan population: A nationwide analysis. BMC Health Serv Res 2008, 8:153.
21. Lee W.C., Huang T.P. Explanatory ability of the ACG system regarding the utilization and expenditure of the national health insurance population in Taiwan-a 5-year analysis. JChin Med Assoc 2008, 71:191-199.
22. Tao P., Lin M.H., Peng L.N., et al. Reducing the burden of morbidity and medical utilization of older patients by outpatient geriatric services: Implications to primary health-care settings. Geriatr Gerontol Int 2012, 12:612-621.
23. Lu J.F., Hsiao W.C. Does universal health insurance make health care unaffordable? Lessons from Taiwan. Health Aff (Millwood) 2003, 22:77-88.
24. BNHI Regulations Governing Examination of Medical Care Services for National Health Insurance Medical Care Institutions 2012, Bureau of National Health Insurance, Taipei.
25. The Johns Hopkins ACG® System Techinical Reference Guide 9.0 ed 2009, John Hopkins, Baltimore.
26. Saliba D., Elliott M., Rubenstein L.Z., et al. The Vulnerable Elders Survey: a tool for identifying vulnerable older people in the community. JAm Geriatr Soc 2001, 49:1691-1699.
27. Wu J.C., Chen Y.C., Liu L., et al. Effects of age, gender, and socio-economic status on the incidence of spinal cord injury: an assessment using the eleven-year comprehensive nationwide database of Taiwan. JNeurotrauma 2012, 29:889-897.
28. Chang W.C., Lan T.H., Ho W.C., Lan T.Y. Factors affecting the use of health examinations by the elderly in Taiwan. Arch Gerontol Geriatr 2010, 50:S11-S16.
29. Tsai Y.W., Huang W.F., Wen Y.W., Chen P.F. The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan. Value Health 2007, 10:117-127.
30. Liu C.Y., Hung Y.T., Chuang Y.L., et al. Incorporating development stratification of Taiwan townships into sampling design of large scale health interview survey. Journal of Health Management 2006, 4:1-22.
31. Simonsen L., Taylor R.J., Viboud C., et al. Mortality benefits of influenza vaccination in elderly people: An ongoing controversy. Lancet Infect Dis 2007, 7:658-666.
32. Chiu P.J., Chen C.H., Chih Y.C. Effectiveness of the influenza vaccination program for the elderly in Taiwan. Vaccine 2013, 31:632-638.
33. Ho T.Y., Huang K.Y., Huang T.T., et al. The impact of influenza vaccinations on the adverse effects and hospitalization rate in the elderly: A national based study in an Asian country. PLoS One 2012, 7:e50337.
34. Wang I.K., Lin C.L., Chang Y.C., et al. Effectiveness of influenza vaccination in elderly diabetic patients: A retrospective cohort study. Vaccine 2013, 31:718-724.
35. Cai S., Temkin-Greener H. Influenza vaccination and its impact on hospitalization events in nursing homes. JAm Med Dir Assoc 2011, 12:493-498.
36. Arden N., Monto A.S., Ohmit S.E. Vaccine use and the risk of outbreaks in a sample of nursing homes during an influenza epidemic. Am J Public Health 1995, 85:399-401.
37. Wang S.T., Lee L.T., Chen L.S., Chen T.H. Economic evaluation of vaccination against influenza in the elderly: An experience from a population-based influenza vaccination program in Taiwan. Vaccine 2005, 23:1973-1980.
38. Gross P.A., Hermogenes A.W., Sacks H.S., et al. The efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literature. Ann Intern Med 1995, 123:518-527.
39. Dexter L.J., Teare M.D., Dexter M., et al. Strategies to increase influenza vaccination rates: Outcomes of a nationwide cross-sectional survey of UK general practice. BMJ Open 2012, 2:e000851.
40. Prevention and control of influenza pandemics and annual epidemics. In: World Health Organization. 56th World Health Assembly 2003, 19. World Health Organization, 56th World Health Assembly:WHA56, Geneva, Switzerland, 1-3.
41. Nichol K.L., Nordin J.D., Nelson D.B., et al. Effectiveness of influenza vaccine in the community-dwelling elderly. NEngl J Med 2007, 357:1373-1381.