Opposite regulatory effects of IFN-β and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages

Journal of Leukocyte Biology

Volumn 95, Issue 1, 2014, Pages 161-168

  Cardone, Marco ^a   Ikeda, Kyojiro N ^a   Varano, Barbara ^a   Belardelli, Filippo ^a   Millefiorini, Enrico ^b   Gessani, Sandra ^a   Conti, Lucia ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cell differentiation; Cytokines; Pathogen recognition

Indexed keywords

BETA INTERFERON; CD209 ANTIGEN; DECTIN 1; INTERLEUKIN 3; ANTIGEN; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; CYTOKINE; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN; IMMUNOGLOBULIN RECEPTOR; LECTIN; MRC1 PROTEIN, HUMAN;

ANTIGEN PRESENTATION; ARTICLE; CANDIDA ALBICANS; CELL DIFFERENTIATION; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTERNALIZATION; MACROPHAGE; MONOCYTE; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UPREGULATION; DENDRITIC CELL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MICROBIOLOGY; PATHOGEN RECOGNITION;

CELL DIFFERENTIATION; CYTOKINES; PATHOGEN RECOGNITION;

ANTIGENS; CANDIDA ALBICANS; CELL ADHESION MOLECULES; DENDRITIC CELLS; ENDOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-BETA; INTERLEUKIN-3; LECTINS, C-TYPE; MACROPHAGE ACTIVATION; MACROPHAGES; MONOCYTES; PHAGOCYTOSIS; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC;

EID: 84897019007     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0313168     Document Type: Article

References (39)

1. Areschoug, T., Gordon, S. (2008) Pattern recognition receptors and their role in innate immunity: focus on microbial protein ligands. Contributions to microbiology 15, 45-60.
2. Kerrigan, A. M., Brown, G. D. (2009) C-type lectins and phagocytosis. Immunobiology 214, 562-575.
3. Taylor, P. R., Gordon, S., Martinez-Pomares, L. (2005) The mannose receptor: linking homeostasis and immunity through sugar recognition. Trends Immunol 26, 104-110.
4. Martinez-Pomares, L. (2012) The mannose receptor. J Leukoc Biol 92, 1177-1186.
5. Faure, M., Rabourdin-Combe, C. (2011) Innate immunity modulation in virus entry. Current opinion in virology 1, 6-12.
6. Hollmig, S. T., Ariizumi, K., Cruz, P. D., Jr. (2009) Recognition of nonself-polysaccharides by C-type lectin receptors dectin-1 and dectin-2. Glycobiology 19, 568-575.
7. Drummond, R. A., Brown, G. D. (2011) The role of Dectin-1 in the host defence against fungal infections. Current opinion in microbiology 14, 392-399.
8. Goodridge, H. S., Reyes, C. N., Becker, C. A., Katsumoto, T. R., Ma, J., Wolf, A. J., Bose, N., Chan, A. S., Magee, A. S., Danielson, M. E., Weiss, A., Vasilakos, J. P., Underhill, D. M. (2011) Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature 472, 471-475.
9. Shepherd, V. L., Campbell, E. J., Senior, R. M., Stahl, P. D. (1982) Characterization of the mannose/fucose receptor on human mononuclear phagocytes. Journal of the Reticuloendothelial Society 32, 423-431.
10. Avrameas, A., McIlroy, D., Hosmalin, A., Autran, B., Debre, P., Monsigny, M., Roche, A. C., Midoux, P. (1996) Expression of a mannose/fucose membrane lectin on human dendritic cells. Eur J Immunol 26, 394-400.
11. Hermanz-Falcon, P., Arce, I., Roda-Navarro, P., Fernandez-Ruiz, E. (2001) Cloning of human DECTIN-1, a novel C-type lectin-like receptor gene expressed on dendritic cells. Immunogenetics 53, 288-295.
12. Montaner, L. J., da Silva, R. P., Sun, J., Sutterwala, S., Hollinshead, M., Vaux, D., Gordon, S. (1999) Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10. J Immunol 162, 4606-4613.
13. Willment, J. A., Lin, H. H., Reid, D. M., Taylor, P. R., Williams, D. L., Wong, S. Y., Gordon, S., Brown, G. D. (2003) Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol 171, 4569-4573.
14. Mogensen, S. C., Virelizier, J. L. (1987) The interferon-macrophage alliance. Interferon 8, 55-84.
15. Martinez-Moczygemba, M., Huston, D. P. (2003) Biology of common beta receptor-signaling cytokines: IL-3, IL-5, and GM-CSF. J Allergy Clin Immunol 112, 653-665; quiz 666.
16. Sabbatucci, M., Purificato, C., Fantuzzi, L., Gessani, S. (2011) Toll-like receptor cross-talk in human monocytes regulates CC-chemokine production, antigen uptake and immune cell recruitment. Immunobiology 216, 1135-1142.
17. Conti, L., Cardone, M., Varano, B., Puddu, P., Belardelli, F., Gessani, S. (2008) Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes. Eur J Immunol 38, 750-762.
18. Saresella, M., Roda, K., Speciale, L., Taramelli, D., Mendozzi, E., Guerini, F., Ferrante, P. (1997) A rapid evaluation of phagocytosis and killing of Candida albicans by CD13+ leukocytes. J Immunol Methods 210, 227-234.
19. Peirson, S. N., Butler, J. N., Foster, R. G. (2003) Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31, e73.
20. Rouleux-Bonnin, F., Monsigny, M., Legrand, A. (1995) Transcriptional expression of mannose receptor gene during differentiation of human macrophages. Biochem Biophys Res Commun 217, 106-112.
21. Wang, M., Friedman, H., Djeu, J. Y. (1989) Enhancement of human monocyte function against Candida albicans by the colony-stimulating factors (CSF): IL-3, granulocyte-macrophage-CSF, and macrophage-CSF. J Immunol 143, 671-677.
22. Testa, U., Conti, L., Sposi, N. M., Varano, B., Tritarelli, E., Malorni, W., Samoggia, P., Rainaldi, G., Peschle, C., Belardelli, F., et al. (1995) IFNbeta selectively down-regulates transferrin receptor expression in human peripheral blood macrophages by a post-translational mechanism. J Immunol 155, 427-435.
23. Netea, M. G., Gow, N. A., Munro, C. A., Bates, S., Collins, C., Ferwerda, G., Hobson, R. P., Bertram, G., Hughes, H. B., Jansen, T., Jacobs, L., Buurman, E. T., Gijzen, K., Williams, D. L., Torensma, R., McKinnon, A., MacCallum, D. M., Odds, F. C., Van der Meer, J. W., Brown, A. J., Kullberg, B. J. (2006) Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest 116, 1642-1650.
24. Heinsbroek, S. E., Taylor, P. R., Martinez, F. O., Martinez-Pomares, L., Brown, G. D., Gordon, S. (2008) Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis. PLoS Pathog 4, e1000218.
25. Steinman, R. M., Hemmi, H. (2006) Dendritic cells: translating innate to adaptive immunity. Curr Top Microbiol Immunol 311, 17-58.
26. Gauzzi, M. C., Canini, I., Eid, P., Belardelli, F., Gessani, S. (2002) Loss of type I IFN receptors and impaired IFN responsiveness during terminal maturation of monocyte-derived human dendritic cells. J Immunol 169, 3038-3045.
27. Santini, S. M., Lapenta, C., Logozzi, M., Parlato, S., Spada, M., Di Pucchio, T., Belardelli, F. (2000) Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J Exp Med 191, 1777-1788.
28. Jensen, J., Vazquez-Torres, A., Balish, E. (1992) Poly(I. C)-induced interferons enhance susceptibility of SCID mice to systemic candidiasis. Infect Immun 60, 4549-4557.
29. Guarda, G., Braun, M., Staehli, F., Tardivel, A., Mattmann, C., Forster, I., Farlik, M., Decker, T., Du Pasquier, R. A., Romero, P., Tschopp, J. (2011) Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34, 213-223.
30. Ezekowitz, R. A., Hill, M., Gordon, S. (1986) Interferon alpha/beta selectively antagonises down-regulation of mannosyl-fucosyl receptors on activated macrophages by interferon gamma. Biochem Biophys Res Commun 136, 737-744.
31. Mokoena, T., Gordon, S. (1985) Human macrophage activation. Modulation of mannosyl, fucosyl receptor activity in vitro by lymphokines, gamma and alpha interferons, and dexamethasone. J Clin Invest 75, 624-631.
32. Conti, L., Gessani, S. (2008) GM-CSF in the generation of dendritic cells from human blood monocyte precursors: recent advances. Immunobiology 213, 859-870.
33. Relloso, M., Puig-Kroger, A., Pello, O. M., Rodriguez-Fernandez, J. L., de la Rosa, G., Longo, N., Navarro, J., Munoz-Fernandez, M. A., Sanchez-Mateos, P., Corbi, A. L. (2002) DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and antiinflammatory agents. J Immunol 168, 2634-2643.
34. Shahangian, A., Chow, E. K., Tian, X., Kang, J. R., Ghaffari, A., Liu, S. Y., Belperio, J. A., Cheng, G., Deng, J. C. (2009) Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. J Clin Invest 119, 1910-1920.
35. Wang, J., Nikrad, M. P., Travanty, E. A., Zhou, B., Phang, T., Gao, B., Alford, T., Ito, Y., Nahreini, P., Hartshorn, K., Wentworth, D., Dinarello, C. A., Mason, R. J. (2012) Innate immune response of human alveolar macrophages during influenza A infection. Plos One 7, e29879.
36. Maffione, A. B., Tato, E., Losito, S., Nacci, C., Mitolo, V., Troiano, M., Ruggieri, M., Livrea, P., Jirillo, E. (2000) In vivo effects of recombinantinterferon-beta1b treatment on polymorphonuclear cell and monocyte functions and on T-cell-mediated antibacterial activity in patients with relapsing-remitting multiple sclerosis. Immunopharmacology and immunotoxicology 22, 1-18.
37. Monrad, S. U., Rea, K., Thacker, S., Kaplan, M. J. (2008) Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus. Arthritis Res Ther 10, R114.
38. Allavena, P., Chieppa, M., Bianchi, G., Solinas, G., Fabbri, M., Laskarin, G., Mantovani, A. (2010) Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages. Clinical & Developmental Immunology 2010, 547179.
39. Gresser, I., Belardelli, F. (2002) Endogenous type I interferons as a defense against tumors. Cytokine Growth Factor Rev 13, 111-118.