메뉴 건너뛰기




Volumn 111, Issue 12, 2014, Pages 4578-4583

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

Author keywords

[No Author keywords available]

Indexed keywords

LEVODOPA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 84897010488     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401819111     Document Type: Article
Times cited : (87)

References (41)
  • 1
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • Kish SJ, Shannak K, Hornykiewicz O (1988) Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 318(14):876-880. (Pubitemid 18090271)
    • (1988) New England Journal of Medicine , vol.318 , Issue.14 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 2
    • 79959869606 scopus 로고    scopus 로고
    • Modulation of striatal projection systems by dopamine
    • Gerfen CR, Surmeier DJ (2011) Modulation of striatal projection systems by dopamine. Annu Rev Neurosci 34:441-466.
    • (2011) Annu Rev Neurosci , vol.34 , pp. 441-466
    • Gerfen, C.R.1    Surmeier, D.J.2
  • 3
    • 0025355032 scopus 로고
    • Levodopa-induced dyskinesia: Review, observations, and speculations
    • Nutt JG (1990) Levodopa-induced dyskinesia: Review, observations, and speculations. Neurology 40(2):340-345.
    • (1990) Neurology , vol.40 , Issue.2 , pp. 340-345
    • Nutt, J.G.1
  • 4
    • 14944354884 scopus 로고    scopus 로고
    • Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years
    • DOI 10.1002/mds.20324
    • Hely MA, Morris JG, Reid WG, Trafficante R (2005) Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years. Mov Disord 20(2):190-199. (Pubitemid 40361122)
    • (2005) Movement Disorders , vol.20 , Issue.2 , pp. 190-199
    • Hely, M.A.1    Morris, J.G.L.2    Reid, W.G.J.3    Trafficante, R.4
  • 5
    • 0031925945 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
    • DOI 10.1046/j.1460-9568.1998.00285.x
    • Cenci MA, Lee CS, Björklund A (1998) L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. Eur J Neurosci 10(8):2694-2706. (Pubitemid 28362576)
    • (1998) European Journal of Neuroscience , vol.10 , Issue.8 , pp. 2694-2706
    • Cenci, M.A.1    Lee, C.S.2    Bjorklund, A.3
  • 8
    • 34047178328 scopus 로고    scopus 로고
    • Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA-Induced Dyskinesia and the Role of Dopamine D1 Receptors
    • DOI 10.1016/j.biopsych.2006.11.032, PII S0006322306015514, Molecular Mechanisms, Brain Development, and Novel Treatment Mechanisms for Schizophrenia
    • Westin JE, Vercammen L, Strome EM, Konradi C, Cenci MA (2007) Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA- induced dyskinesia and the role of dopamine D1 receptors. Biol Psychiatry 62(7):800-810. (Pubitemid 47374647)
    • (2007) Biological Psychiatry , vol.62 , Issue.7 , pp. 800-810
    • Westin, J.E.1    Vercammen, L.2    Strome, E.M.3    Konradi, C.4    Cenci, M.A.5
  • 10
    • 70349572635 scopus 로고    scopus 로고
    • Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia
    • Santini E, Heiman M, Greengard P, Valjent E, Fisone G (2009) Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia. Sci Signal 2(80):ra36.
    • (2009) Sci Signal , vol.2 , Issue.80
    • Santini, E.1    Heiman, M.2    Greengard, P.3    Valjent, E.4    Fisone, G.5
  • 11
    • 62449156198 scopus 로고    scopus 로고
    • Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy
    • Crittenden JR, et al. (2009) Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy. Proc Natl Acad Sci USA 106(8):2892-2896.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.8 , pp. 2892-2896
    • Crittenden, J.R.1
  • 12
    • 68949172388 scopus 로고    scopus 로고
    • Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation
    • Darmopil S, Martín AB, De Diego IR, Ares S, Moratalla R (2009) Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation. Biol Psychiatry 66(6):603-613.
    • (2009) Biol Psychiatry , vol.66 , Issue.6 , pp. 603-613
    • Darmopil, S.1    Martín, A.B.2    De Diego, I.R.3    Ares, S.4    Moratalla, R.5
  • 13
    • 77955380256 scopus 로고    scopus 로고
    • Maladaptive striatal plasticity in L-DOPA-induced dyskinesia
    • Cenci MA, Konradi C (2010) Maladaptive striatal plasticity in L-DOPA-induced dyskinesia. Prog Brain Res 183:209-233.
    • (2010) Prog Brain Res , vol.183 , pp. 209-233
    • Cenci, M.A.1    Konradi, C.2
  • 14
    • 0026600262 scopus 로고
    • Selective D2 receptor stimulation induces dyskinesia in parkinsonian monkeys
    • Luquin MR, Laguna J, Obeso JA (1992) Selective D2 receptor stimulation induces dyskinesia in parkinsonian monkeys. Ann Neurol 31(5):551-554.
    • (1992) Ann Neurol , vol.31 , Issue.5 , pp. 551-554
    • Luquin, M.R.1    Laguna, J.2    Obeso, J.A.3
  • 15
    • 0033540728 scopus 로고    scopus 로고
    • 1 receptor blockade improves L-dopa-induced dyskinesia but worsens parkinsonism in MPTP monkeys
    • Grondin R, Doan VD, Grégoire L, Bédard PJ (1999) D1 receptor blockade improves L-dopa-induced dyskinesia but worsens parkinsonism in MPTP monkeys. Neurology 52(4):771-776. (Pubitemid 29120183)
    • (1999) Neurology , vol.52 , Issue.4 , pp. 771-776
    • Grondin, R.1    Doan, V.D.2    Gregoire, L.3    Bedard, P.J.4
  • 16
    • 28144463965 scopus 로고    scopus 로고
    • Validation of the L-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists
    • DOI 10.1016/j.brainresbull.2004.10.011, PII S0361923004002758
    • Monville C, Torres EM, Dunnett SB (2005) Validation of the L-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists. Brain Res Bull 68(1-2):16-23. (Pubitemid 41698872)
    • (2005) Brain Research Bulletin , vol.68 , Issue.1-2 , pp. 16-23
    • Monville, C.1    Torres, E.M.2    Dunnett, S.B.3
  • 17
    • 37549025843 scopus 로고    scopus 로고
    • RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease
    • Gold SJ, et al. (2007) RGS9-2 negatively modulates L-3,4- dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. J Neurosci 27(52):14338-14348.
    • (2007) J Neurosci , vol.27 , Issue.52 , pp. 14338-14348
    • Gold, S.J.1
  • 18
    • 70350048909 scopus 로고    scopus 로고
    • Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease
    • Lindgren HS, Ohlin KE, Cenci MA (2009) Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease. Neuropsychopharmacology 34(12):2477-2488.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.12 , pp. 2477-2488
    • Lindgren, H.S.1    Ohlin, K.E.2    Cenci, M.A.3
  • 19
    • 2342459797 scopus 로고    scopus 로고
    • A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: Relation to motor and cellular parameters of nigrostriatal function
    • DOI 10.1016/j.nbd.2004.01.007, PII S0969996104000178
    • Lundblad M, Picconi B, Lindgren H, Cenci MA (2004) A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: Relation to motor and cellular parameters of nigrostriatal function. Neurobiol Dis 16(1):110-123. (Pubitemid 38569802)
    • (2004) Neurobiology of Disease , vol.16 , Issue.1 , pp. 110-123
    • Lundblad, M.1    Picconi, B.2    Lindgren, H.3    Cenci, M.A.4
  • 20
    • 79954630030 scopus 로고    scopus 로고
    • Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease
    • Francardo V, et al. (2011) Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease. Neurobiol Dis 42(3):327-340.
    • (2011) Neurobiol Dis , vol.42 , Issue.3 , pp. 327-340
    • Francardo, V.1
  • 21
    • 55449107738 scopus 로고    scopus 로고
    • A translational profiling approach for the molecular characterization of CNS cell types
    • Heiman M, et al. (2008) A translational profiling approach for the molecular characterization of CNS cell types. Cell 135(4):738-748.
    • (2008) Cell , vol.135 , Issue.4 , pp. 738-748
    • Heiman, M.1
  • 22
    • 84864326726 scopus 로고    scopus 로고
    • DUSPs, to MAP kinases and beyond
    • Huang CY, Tan TH (2012) DUSPs, to MAP kinases and beyond. Cell Biosci 2(1):24.
    • (2012) Cell Biosci , vol.2 , Issue.1 , pp. 24
    • Huang, C.Y.1    Tan, T.H.2
  • 23
    • 0037096360 scopus 로고    scopus 로고
    • D1 Dopamine Receptor Supersensitivity in the Dopamine-Depleted Striatum Results from a Switch in the Regulation of ERK1/2/MAP Kinase
    • Gerfen CR, Miyachi S, Paletzki R, Brown P (2002) D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase. J Neurosci 22(12):5042-5054. (Pubitemid 37465618)
    • (2002) Journal of Neuroscience , vol.22 , Issue.12 , pp. 5042-5054
    • Gerfen, C.R.1    Miyachi, S.2    Paletzki, R.3    Brown, P.4
  • 24
    • 34047114733 scopus 로고    scopus 로고
    • Dopamine dysregulation of movement control in l-DOPA-induced dyskinesia
    • DOI 10.1016/j.tins.2007.03.005, PII S0166223607000665, Fifty years of dopamine research
    • Cenci MA (2007) Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia. Trends Neurosci 30(5):236-243. (Pubitemid 46654236)
    • (2007) Trends in Neurosciences , vol.30 , Issue.5 , pp. 236-243
    • Cenci, M.A.1
  • 26
    • 62149114138 scopus 로고    scopus 로고
    • Dual-specificity phosphatases: Critical regulators with diverse cellular targets
    • Patterson KI, Brummer T, O'Brien PM, Daly RJ (2009) Dual-specificity phosphatases: Critical regulators with diverse cellular targets. Biochem J 418(3):475-489.
    • (2009) Biochem J , vol.418 , Issue.3 , pp. 475-489
    • Patterson, K.I.1    Brummer, T.2    O'Brien, P.M.3    Daly, R.J.4
  • 27
    • 84876580265 scopus 로고    scopus 로고
    • SwissRegulon, a database of genome-wide annotations of regulatory sites: Recent updates
    • Pachkov M, Balwierz PJ, Arnold P, Ozonov E, van Nimwegen E (2013) SwissRegulon, a database of genome-wide annotations of regulatory sites: Recent updates. Nucleic Acids Res 41(Database issue):D214-D220.
    • (2013) Nucleic Acids Res , vol.41 , Issue.DATABASE ISSUE
    • Pachkov, M.1    Balwierz, P.J.2    Arnold, P.3    Ozonov, E.4    Van Nimwegen, E.5
  • 28
    • 78649723150 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats
    • Cantuti-Castelvetri I, et al. (2010) Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. PLoS ONE 5(11):e13861.
    • (2010) PLoS ONE , vol.5 , Issue.11
    • Cantuti-Castelvetri, I.1
  • 29
    • 0033428178 scopus 로고    scopus 로고
    • Striatal fosB expression is causally linked with L-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease
    • DOI 10.1006/nbdi.1999.0259
    • Andersson M, Hilbertson A, Cenci MA (1999) Striatal fosB expression is causally linked with L-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease. Neurobiol Dis 6(6):461-474. (Pubitemid 30036616)
    • (1999) Neurobiology of Disease , vol.6 , Issue.6 , pp. 461-474
    • Andersson, M.1    Hilbertson, A.2    Cenci, M.A.3
  • 30
    • 33644524383 scopus 로고    scopus 로고
    • B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK
    • DOI 10.1038/sj.emboj.7600980, PII 7600980
    • Letourneux C, Rocher G, Porteu F (2006) B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK. EMBO J 25(4):727-738. (Pubitemid 43292435)
    • (2006) EMBO Journal , vol.25 , Issue.4 , pp. 727-738
    • Letourneux, C.1    Rocher, G.2    Porteu, F.3
  • 31
    • 5044225158 scopus 로고    scopus 로고
    • Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase itch
    • DOI 10.1126/science.1099414
    • Gao M, et al. (2004) Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch. Science 306(5694):271-275. (Pubitemid 39336871)
    • (2004) Science , vol.306 , Issue.5694 , pp. 271-275
    • Gao, M.1    Labuda, T.2    Xia, Y.3    Gallagher, E.4    Fang, D.5    Liu, Y.-C.6    Karin, M.7
  • 32
    • 84881558752 scopus 로고    scopus 로고
    • Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease
    • Warren OC, et al. (2013) Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease. Mov Disord 28(8):1064-1071.
    • (2013) Mov Disord , vol.28 , Issue.8 , pp. 1064-1071
    • Warren, O.C.1
  • 33
    • 0035798093 scopus 로고    scopus 로고
    • The neurobiology of slow synaptic transmission
    • Greengard P (2001) The neurobiology of slow synaptic transmission. Science 294(5544):1024-1030.
    • (2001) Science , vol.294 , Issue.5544 , pp. 1024-1030
    • Greengard, P.1
  • 34
    • 0032695796 scopus 로고    scopus 로고
    • Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on G protein-mediated signaling pathways
    • Posner BA, Gilman AG, Harris BA (1999) Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on G protein-mediated signaling pathways. J Biol Chem 274(43):31087-31093.
    • (1999) J Biol Chem , vol.274 , Issue.43 , pp. 31087-31093
    • Posner, B.A.1    Gilman, A.G.2    Harris, B.A.3
  • 35
    • 0033603315 scopus 로고    scopus 로고
    • Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling
    • Druey KM, et al. (1999) Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling. J Biol Chem 274(26):18836-18842.
    • (1999) J Biol Chem , vol.274 , Issue.26 , pp. 18836-18842
    • Druey, K.M.1
  • 36
    • 77953212932 scopus 로고    scopus 로고
    • The small-conductance calcium-activated potassium channel is a key modulator of firing and long-term depression in the dorsal striatum
    • Hopf FW, Seif T, Mohamedi ML, Chen BT, Bonci A (2010) The small-conductance calcium-activated potassium channel is a key modulator of firing and long-term depression in the dorsal striatum. Eur J Neurosci 31(11):1946-1959.
    • (2010) Eur J Neurosci , vol.31 , Issue.11 , pp. 1946-1959
    • Hopf, F.W.1    Seif, T.2    Mohamedi, M.L.3    Chen, B.T.4    Bonci, A.5
  • 38
    • 84875943880 scopus 로고    scopus 로고
    • GPR39 up-regulation after selective antidepressants
    • Młyniec K, Nowak G (2013) GPR39 up-regulation after selective antidepressants. Neurochem Int 62(7):936-939.
    • (2013) Neurochem Int , vol.62 , Issue.7 , pp. 936-939
    • Młyniec, K.1    Nowak, G.2
  • 39
    • 5544325468 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells
    • DOI 10.1007/s00441-004-0974-7
    • Perlmann T, Wallén-Mackenzie A (2004) Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells. Cell Tissue Res 318(1):45-52. (Pubitemid 39366053)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 45-52
    • Perlmann, T.1    Wallen-Mackenzie, A.2
  • 40
    • 27844547616 scopus 로고    scopus 로고
    • The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease
    • DOI 10.1016/j.pneurobio.2005.09.001, PII S0301008205001024
    • Jankovic J, Chen S, Le WD (2005) The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease. Prog Neurobiol 77(1-2):128-138. (Pubitemid 41654775)
    • (2005) Progress in Neurobiology , vol.77 , Issue.1-2 , pp. 128-138
    • Jankovic, J.1    Chen, S.2    Le, W.D.3
  • 41
    • 0033864014 scopus 로고    scopus 로고
    • Prevention and therapeutic strategies for levodopa-induced dyskinesias in Parkinson's disease
    • Ferreira JJ, Rascol O (2000) Prevention and therapeutic strategies for levodopa-induced dyskinesias in Parkinson's disease. Curr Opin Neurol 13(4):431-436.
    • (2000) Curr Opin Neurol , vol.13 , Issue.4 , pp. 431-436
    • Ferreira, J.J.1    Rascol, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.