Increased cutaneous absorption reflects impaired barrier function of reconstructed skin models mimicking keratinisation disorders

Experimental Dermatology

Volumn 23, Issue 4, 2014, Pages 286-288

  Eckl, Katja Martina ^a,b   Weindl, Günther ^c   Ackermann, Katharina ^c   Küchler, Sarah ^c   Casper, Ramona ^b   Radowski, Michal R ^c   Haag, Rainer ^c   Hennies, Hans Christian ^a,b,d   Schäfer Korting, Monika ^c  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF COLOGNE   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Epidermal barrier; Keratinization disorder; Nanoparticles; Skin disease models; Skin permeation and penetration

Indexed keywords

CAFFEINE; EPIDERMAL LIPOXYGENASE 3; LIPOXYGENASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SOLID LIPID NANOPARTICLE; TESTOSTERONE; TRANSGLUTAMINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CONGENITAL ICHTHYOSIFORM ERYTHRODERMA; CONTROLLED STUDY; ERYTHEMA; FIBROBLAST; GENE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; ICHTHYOSIS; KERATINOCYTE; PERMEABILITY BARRIER; PHENOTYPE; SKIN ABSORPTION; SKIN DISEASE; SKIN PENETRATION; 3T3 CELL LINE; AGED; ANIMAL; CHILD; COMPARATIVE STUDY; MALE; METABOLISM; MOUSE; TISSUE ENGINEERING;

3T3 CELLS; AGED; ANIMALS; CHILD; FIBROBLASTS; HUMANS; ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL; KERATINOCYTES; MALE; MICE; SKIN ABSORPTION; TISSUE ENGINEERING;

EID: 84896994658     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/exd.12366     Document Type: Article

References (12)

1. Krug M, Oji V, Traupe H et al. J Dtsch Dermatol Ges 2009: 7: 577-588.
2. Oji V, Eckl K M, Aufenvenne K et al. Am J Hum Genet 2010: 87: 274-281.
3. Eckl K M, Alef T, Torres S et al. J Invest Dermatol 2011: 131: 1938-1942.
4. Korting H C, Schäfer-Korting M. Handb Exp Pharmacol 2010: 197: 435-468.
5. Aufenvenne K, Larcher F, Hausser I et al. Am J Hum Genet 2013: 93: 620-630.
6. Schäfer-Korting M, Bock U, Diembeck W et al. Altern Lab Anim 2008: 36: 161-187.
7. Lombardi Borgia S, Regehly M, Sivaramakrishnan R et al. J Control Release 2005: 110: 151-163.
8. Haag R, Kratz F. Angew Chem Int Ed Engl 2006: 45: 1198-1215.
9. Küchler S, Radowski M R, Blaschke T et al. Eur J Pharm Biopharm 2009: 71: 243-250.
10. Wolf N B, Küchler S, Radowski M R et al. Eur J Pharm Biopharm 2009: 73: 34-42.
11. Ackermann K, Borgia S L, Korting H C et al. Skin Pharmacol Physiol 2010: 23: 105-112.
12. Schäfer-Korting M, Mahmoud A, Lombardi Borgia S et al. Altern Lab Anim 2008: 36: 441-452.