The enigma of Bálint's syndrome: Neural substrates and cognitive deficits

Frontiers in Human Neuroscience

Volumn 8, Issue MAR, 2014, Pages

  Chechlacz, Magdalena ^a   Humphreys, Glyn W ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

B lint's syndrome; Ocular apraxia; Optic ataxia; Posterior cortical atrophy; Simultanagnosia

Indexed keywords

ALZHEIMER DISEASE; APRAXIA; ARTICLE; ATAXIA; BALINT SYNDROME; BOLD SIGNAL; BRAIN ATROPHY; COGNITIVE DEFECT; DISORIENTATION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; NEUROLOGIC DISEASE; SIMULTANAGNOSIA; SYMPTOMATOLOGY; VISUAL FIELD DEFECT; VISUAL STIMULATION; VISUOMOTOR COORDINATION;

EID: 84896991717     PISSN: 16625161     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnhum.2014.00123     Document Type: Article

References (27)

1. Auerbach, S. H., and Alexander, M. P. (1981). Pure agraphia and unilateral optic ataxia associated with a left superior parietal lobule lesion. J. Neurol. Neurosurg. Psychiatry 44, 430-432. doi: 10.1136/jnnp.44.5.430
2. Bálint, R. (1909). Seelenlähmung des "Schauens,"optische Ataxie, räumliche Störung der Aufmerksamkeit. Monatschr. Psychiat. Neurol. 25, 51-81.
3. Benson, D. F., Davis, R. J., and Snyder, B. D. (1988). Posterior cortical atrophy. Arch. Neurol. 45, 789-793. doi: 10.1001/archneur.1988.00520310107024
4. Borchers, S., Muller, L., Synofzik, M., and Himmelbach, M. (2013). Guidelines and quality measures for the diagnosis of optic ataxia. Front. Hum. Neurosci. 7:324. doi: 10.3389/fnhum.2013.00324
5. Cavina-Pratesi, C., Connolly, J. D., and Milner, A. D. (2013). Optic ataxia as a model to investigate the role of the posterior parietal cortex in visually guided action: evidence from studies of patient M.H. Front. Hum. Neurosci. 7:336. doi: 10.3389/fnhum.2013.00336
6. Chechlacz, M., Rotshtein, P., Hansen, P. C., Riddoch, J. M., Deb, S., and Humphreys, G. W. (2012). The neural underpinings of simultanagnosia: disconnecting the visuospatial attention network. J. Cogn. Neurosci. 24, 718-735. doi: 10.1162/jocn_a_00159
7. Dalrymple, K. A., Barton, J. J., and Kingstone, A. (2013). A world unglued: simultanagnosia as a spatial restriction of attention. Front. Hum. Neurosci. 7:145. doi: 10.3389/fnhum.2013.00145
8. Damasio, A. R., Tranel, D., and Rizzo, M. (2000). "Disorders of complex visual processing," In Principles of Behavioral and Cognitive Neurology, ed M. M. Mesulam (New York, NY: Oxford University Press), 32-72.
9. Ferro, J. M. (1984). Transient inaccuracy in reaching caused by a posterior parietal lobe lesion. J. Neurol. Neurosurg. Psychiatry 47, 1016-1019. doi: 10.1136/jnnp.47.9.1016
10. Hof, P. R., Bouras, C., Constantinidis, J., and Morrison, J. H. (1990). Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome. J. Neuropathol. Exp. Neurol. 49, 168-184. doi: 10.1097/00005072-199003000-00008
11. Husain, M., and Stein, J. (1988). Rezso Balint and his most celebrated case. Arch. Neurol. 45, 89-93. doi: 10.1001/archneur.1988.00520250095029
12. Jackson, S. R., Newport, R., Mort, D., and Husain, M. (2005). Where the eye looks, the hand follows; limb-dependent magnetic misreaching in optic ataxia. Curr. Biol. 15, 42-46. doi: 10.1016/j.cub.2004.12.063
13. Karnath, H. O., Ferber, S., Rorden, C., and Driver, J. (2000). The fate of global information in dorsal simultanagnosia. Neurocase 6, 295-305. doi: 10.1080/13554790008402778
14. Karnath, H. O., and Perenin, M. T. (2005). Cortical control of visually guided reaching: evidence from patients with optic ataxia. Cereb. Cortex 15, 1561-1569. doi: 10.1093/cercor/bhi034
15. Khan, A. Z., Pisella, L., Delporte, L., Rode, G., and Rossetti, Y. (2013). Testing for optic ataxia in a blind field. Front. Hum. Neurosci. 7:399. doi: 10.3389/fnhum.2013.00399
16. Meek, B. P., Locheed, K., Lawrence-Dewar, J. M., Shelton, P., and Marotta, J. J. (2013a). Posterior cortical atrophy: an investigation of scan paths generated during face matching tasks. Front. Hum. Neurosci. 7:309. doi: 10.3389/fnhum.2013.00309
17. Meek, B. P., Shelton, P., and Marotta, J. J. (2013b). Posterior cortical atrophy: visuomotor deficits in reaching and grasping. Front. Hum. Neurosci. 7:294. doi: 10.3389/fnhum.2013.00294
18. Mevorach, C., Shalev, L., Green, R. J., Chechlacz, M., Riddoch, J., and Humphreys, G. W. (2013). Hierarchical processing in Balint's syndrome: a failure of flexible top-down attention. Front. Hum. Neurosci. 8:113. doi: 10.3389/fnhum.2014.00113
19. Perenin, M. T., and Vighetto, A. (1988). Optic ataxia: a specific disruption in visuomotor mechanisms. I. Different aspects of the deficit in reaching for objects. Brain 111, 643-674. doi: 10.1093/brain/111.3.643
20. Ptak, R., and Muri, R. M. (2013). The parietal cortex and saccade planning: lessons from human lesion studies. Front. Hum. Neurosci. 7:254. doi: 10.3389/fnhum.2013.00254
21. Rennig, J., Bilalic, M., Huberle, E., Karnath, H. O., and Himmelbach, M. (2013a). The temporo-parietal junction contributes to global gestalt perceptionevidence from studies in chess experts. Front. Hum. Neurosci. 7:513. doi: 10.3389/fnhum.2013.00513
22. Rennig, J., Karnath, H. O., and Huberle, E. (2013b). The role of size constancy for the integration of local elements into a global shape. Front. Hum. Neurosci. 7:342. doi: 10.3389/fnhum.2013.00342
23. Rizzo, M. (1993). 'Balint's syndrome' and associated visuospatial disorders. Baillieres. Clin. Neurol. 2, 415-437.
24. Rizzo, M., and Vecera, S. P. (2002). Psychoanatomical substrates of Balint's syndrome. J. Neurol. Neurosurg. Psychiatry 72, 162-178. doi: 10.1136/jnnp.72.2.162
25. Shakespeare, T. J., Yong, K. X., Frost, C., Kim, L. G., Warrington, E. K., and Crutch, S. J. (2013). Scene perception in posterior cortical atrophy: categorization, description and fixation patterns. Front. Hum. Neurosci. 7:621. doi: 10.3389/fnhum.2013.00621
26. Shalev, L., Humphreys, G. W., and Mevorach, C. (2005). Global processing of compound letters in a patient with Balint's syndrome. Cogn. Neuropsychol. 22, 737-751. doi: 10.1080/02643290442000284
27. Wolpert, I. (1924). Die Simultanagnosie. Z. Gesamte Neurol. Psychiatry 93, 397-415. doi: 10.1007/BF02900065