Incidence of adverse drug events in an academic hospital: A prospective cohort study

International Journal for Quality in Health Care

Volumn 25, Issue 6, 2013, Pages 648-655

  Aljadhey, Hisham ^a   Mahmoud, Mansour A ^a   Mayet, Ahmed ^a   Alshaikh, Mashael ^a,b   Ahmed, Yusuf ^a   Murray, Michael D ^c   Bates, David W ^d  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^c PURDUE UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Drug errors; Hospital care; Patient safety; Setting of care

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; DIURETIC AGENT; GASTROINTESTINAL AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; THYROID HORMONE; TUBERCULOSTATIC AGENT;

ADULT; ADVERSE DRUG REACTION; ARTICLE; COHORT ANALYSIS; FEMALE; HEALTH CARE PERSONNEL; HOSPITAL ADMISSION; HOSPITAL CARE; HUMAN; INTENSIVE CARE UNIT; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MEDICATION ERROR; MIDDLE AGED; OUTCOME ASSESSMENT; PATIENT SAFETY; PHARMACIST; PRIORITY JOURNAL; PROSPECTIVE STUDY; TERTIARY HEALTH CARE; UNSPECIFIED SIDE EFFECT;

DRUG ERRORS; HOSPITAL CARE; PATIENT SAFETY; SETTING OF CARE;

ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICOAGULANTS; ANTIHYPERTENSIVE AGENTS; DIURETICS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; HOSPITALS, TEACHING; HUMANS; INCIDENCE; MALE; MEDICATION ERRORS; MIDDLE AGED; SAUDI ARABIA;

EID: 84896975138     PISSN: 13534505     EISSN: 14643677     Source Type: Journal    
DOI: 10.1093/intqhc/mzt075     Document Type: Article

References (31)

1. Committee on Identifying and Preventing Medication Errors Aspden P, Wolcott J, Bootman JL et al. Editors Preventing Medication Errors. Washington, DC: Institute of Medicine National Academy Press, 2006.
2. Honigman B, Lee J, Rothschild J et al. Using computerized data to identify adverse drug events in outpatients. J Am Med Inform Assoc 2001;8:254-66.
3. Bates DW, Cullen DJ, Laird N et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA 1995;274:29-34.
4. Hug LB, Witkowski DJ, Sox CM et al. Adverse drug event rates in six community hospitals and the potential impact of computerized physician order entry for prevention. J Gen Intern Med 2010;25:31-8.
5. Morimoto T, Sakuma M, Matsui K et al. Incidence of adverse drug events and medication errors in Japan: the JADE study. J Gen Intern Med 2011;26:148-53.
6. Wilson RM, Runciman WB, Gibberd RW et al. The quality in Australian Health Care Study. Med J Aust 1995;163:458-76.
7. Davis P, Lay-Yee R, Briant R et al. Adverse events in New Zealand public hospitals II: preventability and clinical context. N Z Med J 2003;116:U624.
8. Benkirane RR, Abouqal R, Haimeur CC et al. Incidence of adverse drug events and medication errors in intensive care units: a prospective multicenter study. J Patient Saf 2009;5:16-22.
9. Al-Dhawailie A. Inpatient prescribing errors and pharmacist intervention at a teaching hospital in Saudi Arabia. Saudi Pharmaceut J 2011;19:1931-6.
10. Neyaz Y, Qureshi NA, Khoja T et al. Physicians medication prescribing in primary care in Riyadh City, Saudi Arabia. Literature review, Part 1: variations in drug prescribing. East Mediterr Health J 2011;17:126-31.
11. Khoja T, Qureshi NA, Neyaz Y et al. Physicians' medication prescribing in primary care in Riyadh City, Saudi Arabia. Literature review, Part 2: rationalprescribing. East Mediterr Health J 2011;17:132-9.
12. Al-Malaq HM, Al-Aqeel SA, Al-Sultan MS. Adverse drug reactions related hospitalization identified by discharge ICD-9 codes in a univeristy hospital in Riyadh. Saudi Med J 2008;29:1145-50.
13. Alahmadi HA. Assessment of patient safety culturein Saudi Arabian hospitals. Qual Saf Health Care 2010;19:1-5.
14. Al-Ghamdi SA, Mahmoud MA, Alammari MA et al. The outcome of pharmacist counseling at the time of hospital discharge: an observational nonrandomized study. Ann Saudi Med 2012;32:492-7.
15. Jha AK, Kuperman GJ, Teich JM et al. Identifying adverse drug events: development of a computer-based monitor and comparison with chart review and stimulated voluntary report. J Am Med Inform Assoc 1998;5:305-14.
16. Gandhi TK, Seger DL, Bates DW. Identifying drug safety issues: from research to practice. Int J Qual Health Care 2000;12:69-76.
17. Morimoto T, Gandhi TK, Seger AC et al. Adverse drug events and medication errors: detection and classification methods. Qual Saf Health Care 2004;13:306-14.
18. The National Coordinating Council for Medication Error Reporting and Prevention. The first ten years. 'Defining the Problem and Developing Solutions', 2005. http://www.nccmerp.org/pdf/reportFinal2005-11-29.pdf (8 October 2013, date last accessed).
19. Charlson ME, Sax FL, MacKenzie CR et al. Assessing illness severity: does clinical judgment work? J Chronic Dis 1986;39:439-52.
20. Charlson ME, Pompei P, Ales KL et al. A new method of classifying prognostic comorbidity in longitudinal populations: development and validation. J Chron Dis 1987;40:373-83.
21. Poon EG, Cina JL, Churchill W et al. Medication dispensing errors and potential adverse drug events before and after implementing bar code technology in the pharmacy. Ann Intern Med 2006;145:426-34.
22. Cohen MM, Kimmel NL, Benage MK et al. Medication safety program reduces adverse drug events in a community hospital. Qual Saf Health Care 2005;14:169-74.
23. Vira T, Colquhoun M, Etchells E. Reconcilable differences: correcting medication errors at hospital admission and discharge. Qual Saf Health Care 2006;15:122-6.
24. Nester TM, Hale LS. Effectiveness of a pharmacist acquired medication history in promoting patient safety. Am J Health Sys Pharm 2002;59:2221-5.
25. Bond CA, Raehl CL, Franke T. Clinical pharmacy services, pharmacy staffing, and the total cost of care in United States Hospitals. Pharmacotherapy 2000;20:609-21.
26. Bond CA, Raehl CL, Franke T. Clinical pharmacy services and hospital mortality rates. Pharmacotherapy 1999;19:556-64.
27. Bond CA, Raehl CL, Franke T. Clinical pharmacy services, hospital pharmacy staffing, and medication errors in United States hospitals. Pharmacotherapy 2002;22:134-47.
28. Ammenwerth E, Schnell-Inderst P, Machan C et al. The effect of electronic prescribing on medication errors and adverse drug events: a systematic review. JAm Med Inform Assoc 2008;15:585-600.
29. McFadzean E, Isles C, Moffat J et al. Is there a role for a prescribing pharmacist in preventing prescribing errors in a medical admission unit? Pharm J 2003;270:896-9.
30. Strunk LB, Matson AW, Steinke D. Impact of a pharmacist on medication reconciliation on patient admission to a veteran's affairs medical center. Hosp Pharm 2008;43:643-9.
31. Marcilly R, Hackl WO, Luyckx M et al. Scorecards: a new method to prevent adverse drug events? Preliminary results from a clinical field study. Stud Health Technol Inform 2011;166:234-45.