-
1
-
-
67349167635
-
Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
-
BATES, P. J., LABER, D. A., MILLER, D. M., THOMAS, S. D., and TRENT, J. O. (2009). Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer. Exp. Mol. Pathol. 86, 151-164.
-
(2009)
Exp. Mol. Pathol.
, vol.86
, pp. 151-164
-
-
Bates, P.J.1
Laber, D.A.2
Miller, D.M.3
Thomas, S.D.4
Trent, J.O.5
-
2
-
-
36649025655
-
OncomiRs: The discovery and progress of microRNAs in cancers
-
CHO, W. C. (2007). OncomiRs: the discovery and progress of microRNAs in cancers. Mol. Cancer 6, 60.
-
(2007)
Mol. Cancer
, vol.6
, pp. 60
-
-
Cho, W.C.1
-
3
-
-
33745714275
-
Aptamer:toxin conjugates that specifically target prostate tumor cells
-
CHU, T. C., MARKS, J. W., 3rd, LAVERY, L. A., FAULKNER, S., ROSENBLUM, M. G., ELLINGTON, A. D., and LEVY, M. (2006). Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Res. 66, 5989-5992.
-
(2006)
Cancer Res.
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks, J.W.2
Lavery, L.A.3
Faulkner, S.4
Rosenblum, M.G.5
Ellington, A.D.6
Levy, M.7
-
4
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
ELMEN, J., LINDOW, M., SCHUTZ, S., LAWRENCE, M., PETRI, A., OBAD, S., LINDHOLM, M., HEDTJARN, M., HANSEN, H. F., BERGER, U., et al. (2008). LNA-mediated microRNA silencing in non-human primates. Nature 452, 896-899.
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjarn, M.8
Hansen, H.F.9
Berger, U.10
-
5
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
FAROKHZAD, O. C., CHENG, J., TEPLY, B. A., SHERIFI, I., JON, S., KANTOFF, P. W., RICHIE, J. P., and LANGER, R. (2006). Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. U. S. A. 103, 6315-6320.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
Richie, J.P.7
Langer, R.8
-
6
-
-
84863418151
-
Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles
-
KANASTY, R. L., WHITEHEAD, K. A., VEGAS, A. J., and ANDERSON, D. G. (2012). Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles. Mol. Ther. 20,513-524.
-
(2012)
Mol. Ther.
, vol.20
, pp. 513-524
-
-
Kanasty, R.L.1
Whitehead, K.A.2
Vegas, A.J.3
Anderson, D.G.4
-
8
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
LANFORD, R. E., HILDEBRANDT-ERIKSEN, E. S., PETRI, A., PERSSON, R., LINDOW, M., MUNK, M. E., KAUPPINEN, S., and ORUM, H. (2010). Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327, 198-201.
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
Kauppinen, S.7
Orum, H.8
-
9
-
-
0037423845
-
Vertebrate microRNA genes
-
LIM, L. P., GLASNER, M. E., YEKTA, S., BURGE, C. B., and BARTEL, D. P. (2003). Vertebrate microRNA genes. Science 299, 1540.
-
(2003)
Science
, vol.299
, pp. 1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
10
-
-
84861489369
-
MiR-21 down-regulation promotes apoptosis and inhibits invasion and migration abilities of OVCAR3 cells
-
LOU, Y., CUI, Z., WANG, F., YANG, X., and QIAN, J. (2011). miR-21 down-regulation promotes apoptosis and inhibits invasion and migration abilities of OVCAR3 cells. Clin. Invest. Med. 34, E281.
-
(2011)
Clin. Invest. Med.
, vol.34
-
-
Lou, Y.1
Cui, Z.2
Wang, F.3
Yang, X.4
Qian, J.5
-
11
-
-
79955453676
-
Making sense of therapeutics using antisense technology
-
MALIK, R., and ROY, I. (2011). Making sense of therapeutics using antisense technology. Expert Opin. Drug Discov. 6, 507-526.
-
(2011)
Expert Opin. Drug Discov.
, vol.6
, pp. 507-526
-
-
Malik, R.1
Roy, I.2
-
12
-
-
70349786346
-
The chemical biology of aptamers
-
MAYER, G. (2009). The chemical biology of aptamers. Angew Chem. Int. Ed. Engl. 48, 2672-2689.
-
(2009)
Angew Chem. Int. Ed. Engl.
, vol.48
, pp. 2672-2689
-
-
Mayer, G.1
-
13
-
-
78649979777
-
Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures
-
MAYER, G., AHMED, M. S., DOLF, A., ENDL, E., KNOLLE, P. A., and FAMULOK, M. (2010). Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures. Nat. Protoc. 5, 1993-2004.
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1993-2004
-
-
Mayer, G.1
Ahmed, M.S.2
Dolf, A.3
Endl, E.4
Knolle, P.A.5
Famulok, M.6
-
14
-
-
33747031960
-
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
-
MCNAMARA, J. O., 2nd, ANDRECHEK, E. R., WANG, Y., VILES, K. D., REMPEL, R. E., GILBOA, E., SULLENGER, B. A., and GIANGRANDE, P. H. (2006). Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotechnol. 24, 1005-1015.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1005-1015
-
-
McNamara, J.O.1
Andrechek II, E.R.2
Wang, Y.3
Viles, K.D.4
Rempel, R.E.5
Gilboa, E.6
Sullenger, B.A.7
Giangrande, P.H.8
-
15
-
-
76749169748
-
AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia
-
MONGELARD, F., and BOUVET, P. (2010). AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia. Curr. Opin. Mol. Ther. 12, 107-114.
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 107-114
-
-
Mongelard, F.1
Bouvet, P.2
-
16
-
-
79953202455
-
Silencing of microRNA families by seed-targeting tiny LNAs
-
OBAD, S., DOS SANTOS, C. O., PETRI, A., HEIDENBLAD, M., BROOM, O., RUSE, C., FU, C., LINDOW, M., STENVANG, J., STRAARUP, E. M., et al. (2011). Silencing of microRNA families by seed-targeting tiny LNAs. Nat. Genet. 43, 371-378.
-
(2011)
Nat. Genet.
, vol.43
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
Heidenblad, M.4
Broom, O.5
Ruse, C.6
Lindow, M.7
Stenvang, J.8
Straarup, E.M.9
-
17
-
-
78449269097
-
A new paradigm for aptamer therapeutic AS1411 action: Uptake by macropinocytosis and its stimulation by a nucleolindependent mechanism
-
REYES-REYES, E. M., TENG, Y., and BATES, P. J. (2010). A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolindependent mechanism. Cancer Res. 70, 8617-8629.
-
(2010)
Cancer Res.
, vol.70
, pp. 8617-8629
-
-
Reyes-Reyes, E.M.1
Teng, Y.2
Bates, P.J.3
-
18
-
-
77956682609
-
Development of DNA aptamers using Cell-SELEX
-
SEFAH, K., SHANGGUAN, D., XIONG, X., O'DONOGHUE, M. B., and TAN, W. (2010). Development of DNA aptamers using Cell-SELEX. Nat. Protoc. 5, 1169-1185.
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1169-1185
-
-
Sefah, K.1
Shangguan, D.2
Xiong, X.3
O'donoghue, M.B.4
Tan, W.5
-
19
-
-
42049124068
-
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells
-
SOUNDARARAJAN, S., CHEN, W., SPICER, E. K., COURTENAY-LUCK, N., and FERNANDES, D. J. (2008). The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 68, 2358-2365.
-
(2008)
Cancer Res.
, vol.68
, pp. 2358-2365
-
-
Soundararajan, S.1
Chen, W.2
Spicer, E.K.3
Courtenay-Luck, N.4
Fernandes, D.J.5
-
20
-
-
75649138331
-
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents
-
STEIN, C. A., HANSEN, J. B., LAI, J., WU, S., VOSKRESENSKIY, A., HOG, A., WORM, J., HEDTJARN, M., SOULEIMANIAN, N., MILLER, P., et al. (2010). Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents. Nucleic Acids Res. 38, e3.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Stein, C.A.1
Hansen, J.B.2
Lai, J.3
Voskresenskiy, A.4
Hog, A.5
Worm, J.6
Hedtjarn, M.7
Souleimanian, N.8
Miller, P.9
-
21
-
-
35948945681
-
AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin
-
TENG, Y., GIRVAN, A. C., CASSON, L. K., PIERCE, W. M., JR., QIAN, M., THOMAS, S. D., and BATES, P. J. (2007). AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 67, 10491-10500.
-
(2007)
Cancer Res.
, vol.67
, pp. 10491-10500
-
-
Teng, Y.1
Girvan, A.C.2
Casson, L.K.3
Pierce, W.M.4
Qian, M.5
Thomas, S.D.6
Bates, P.J.7
-
22
-
-
43749113595
-
Modulation of miRNA activity in human cancer: A new paradigm for cancer gene therapy
-
TONG, A. W., and NEMUNAITIS, J. (2008). Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy? Cancer Gene Ther. 15, 341-355.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 341-355
-
-
Tong, A.W.1
Nemunaitis, J.2
-
23
-
-
83555171758
-
Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth
-
YAN, L. X., WU, Q. N., ZHANG, Y., LI, Y. Y., LIAO, D. Z., HOU, J. H., FU, J., ZENG, M. S., YUN, J. P., WU, Q. L., et al. (2011). Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth. Breast Cancer Res. 13, R2.
-
(2011)
Breast Cancer Res.
, vol.13
-
-
Yan, L.X.1
Zhang, Y.2
Liao, D.Z.3
Hou, J.H.4
Zeng, M.S.5
Yun, J.P.6
-
24
-
-
80355135153
-
Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery
-
ZHOU, J., LI, H., ZHANG, J., PIOTR, S., and ROSSI, J. (2011). Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery. J. Vis. Exp. 52, 2954.
-
(2011)
J. Vis. Exp.
, vol.52
, pp. 2954
-
-
Zhou, J.1
Zhang, J.2
Piotr, S.3
Rossi, J.4
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