메뉴 건너뛰기




Volumn 9, Issue 3, 2014, Pages 777-784

Colloidal drug formulations can explain "bell-shaped" concentration-response curves

Author keywords

[No Author keywords available]

Indexed keywords

CRIZOTINIB; EVANS BLUE; FULVESTRANT; MONOMER; SORAFENIB; TRYPAN BLUE; ANTINEOPLASTIC AGENT; COLLOID;

EID: 84896953307     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb4007584     Document Type: Article
Times cited : (107)

References (54)
  • 1
    • 0018001339 scopus 로고
    • Simultaneous analysis of families of sigmoidal curves' - 'application to bioassay, radioligand assay, and physiological dose-response curves
    • Delean, A., Munson, P. J., and Rodbard, D. (1978) Simultaneous analysis of families of sigmoidal curves' - 'application to bioassay, radioligand assay, and physiological dose-response curves Am. J. Physiol. 235, E97-E102
    • (1978) Am. J. Physiol. , vol.235
    • Delean, A.1    Munson, P.J.2    Rodbard, D.3
  • 2
    • 84940137432 scopus 로고
    • Zone behavior of enzymes: Illustrated by the effect of dissociation constant and dilution on the system cholinesterase-physostigmine
    • with technical assistance of Frank L. Plachte
    • Straus, O. H. and Goldstein, A. (1943) Zone behavior of enzymes: Illustrated by the effect of dissociation constant and dilution on the system cholinesterase-physostigmine J. Gen. Physiol. 26, 559-585 with technical assistance of Frank L. Plachte
    • (1943) J. Gen. Physiol. , vol.26 , pp. 559-585
    • Straus, O.H.1    Goldstein, A.2
  • 4
    • 33845491449 scopus 로고    scopus 로고
    • Interpreting steep dose-response curves in early inhibitor discovery
    • Shoichet, B. K. (2006) Interpreting steep dose-response curves in early inhibitor discovery J. Med. Chem. 49, 7274-7
    • (2006) J. Med. Chem. , vol.49 , pp. 7274-7277
    • Shoichet, B.K.1
  • 5
    • 0034904233 scopus 로고    scopus 로고
    • The frequency of U-shaped dose responses in the toxicological literature
    • Calabrese, E. J. and Baldwin, L. A. (2001) The frequency of U-shaped dose responses in the toxicological literature Toxicol. Sci. 62, 330-338
    • (2001) Toxicol. Sci. , vol.62 , pp. 330-338
    • Calabrese, E.J.1    Baldwin, L.A.2
  • 6
    • 33750015955 scopus 로고    scopus 로고
    • The mammary gland response to estradiol: Monotonic at the cellular level, non-monotonic at the tissue-level of organization'
    • Vandenberg, L. N., Wadia, P. R., Schaeberle, C. M., Rubin, B. S., Sonnenschein, C., and Soto, A. M. (2006) The mammary gland response to estradiol: Monotonic at the cellular level, non-monotonic at the tissue-level of organization' J. Steroid Biochem. Mol. Biol. 101, 263-274
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.101 , pp. 263-274
    • Vandenberg, L.N.1    Wadia, P.R.2    Schaeberle, C.M.3    Rubin, B.S.4    Sonnenschein, C.5    Soto, A.M.6
  • 8
    • 0024402439 scopus 로고
    • Negative controls of cell proliferation: Human prostate cancer cells and androgens
    • Sonnenschein, C., Olea, N., Pasanen, M. E., and Soto, A. M. (1989) Negative controls of cell proliferation: Human prostate cancer cells and androgens Cancer Res. 49, 3474-3481
    • (1989) Cancer Res. , vol.49 , pp. 3474-3481
    • Sonnenschein, C.1    Olea, N.2    Pasanen, M.E.3    Soto, A.M.4
  • 9
    • 0037732733 scopus 로고    scopus 로고
    • Disruption of androgen regulation in the prostate by the environmental contaminant hexachlorobenzene
    • Ralph, J. L., Orgebin-Crist, M. C., Lareyre, J. J., and Nelson, C. C. (2003) Disruption of androgen regulation in the prostate by the environmental contaminant hexachlorobenzene Environ. Health Perspect. 111, 461-466
    • (2003) Environ. Health Perspect. , vol.111 , pp. 461-466
    • Ralph, J.L.1    Orgebin-Crist, M.C.2    Lareyre, J.J.3    Nelson, C.C.4
  • 10
    • 0036559993 scopus 로고    scopus 로고
    • The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells
    • Wetherill, Y. B., Petre, C. E., Monk, K. R., Puga, A., and Knudsen, K. E. (2002) The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells Mol. Cancer Ther. 1, 515-524
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 515-524
    • Wetherill, Y.B.1    Petre, C.E.2    Monk, K.R.3    Puga, A.4    Knudsen, K.E.5
  • 12
    • 79953029961 scopus 로고    scopus 로고
    • Hormesis provides a generalized quantitative estimate of biological plasticity
    • Calabrese, E. and Mattson, M. (2011) Hormesis provides a generalized quantitative estimate of biological plasticity J. Cell Commun. Signal. 5, 25-38
    • (2011) J. Cell Commun. Signal. , vol.5 , pp. 25-38
    • Calabrese, E.1    Mattson, M.2
  • 13
    • 0030770254 scopus 로고    scopus 로고
    • Allixin, a phytoalexin produced by garlic, and its analogues as novel exogenous substances with neurotrophic activity
    • Moriguchi, T., Matsuura, H., Itakura, Y., Katsuki, H., Saito, H., and Nishiyama, N. (1997) Allixin, a phytoalexin produced by garlic, and its analogues as novel exogenous substances with neurotrophic activity Life Sci. 61, 1413-1420
    • (1997) Life Sci. , vol.61 , pp. 1413-1420
    • Moriguchi, T.1    Matsuura, H.2    Itakura, Y.3    Katsuki, H.4    Saito, H.5    Nishiyama, N.6
  • 15
    • 0037061628 scopus 로고    scopus 로고
    • A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening
    • McGovern, S. L., Caselli, E., Grigorieff, N., and Shoichet, B. K. (2002) A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening J. Med. Chem. 45, 1712-22
    • (2002) J. Med. Chem. , vol.45 , pp. 1712-1722
    • McGovern, S.L.1    Caselli, E.2    Grigorieff, N.3    Shoichet, B.K.4
  • 16
    • 47749106894 scopus 로고    scopus 로고
    • Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors
    • Coan, K. E. D. and Shoichet, B. K. (2008) Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors J. Am. Chem. Soc. 130, 9606-9612
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 9606-9612
    • Coan, K.E.D.1    Shoichet, B.K.2
  • 17
    • 64549152003 scopus 로고    scopus 로고
    • Promiscuous aggregate-based inhibitors promote enzyme unfolding
    • Coan, K. E., Maltby, D. A., Burlingame, A. L., and Shoichet, B. K. (2009) Promiscuous aggregate-based inhibitors promote enzyme unfolding J. Med. Chem. 52, 2067-75
    • (2009) J. Med. Chem. , vol.52 , pp. 2067-2075
    • Coan, K.E.1    Maltby, D.A.2    Burlingame, A.L.3    Shoichet, B.K.4
  • 18
    • 84866914982 scopus 로고    scopus 로고
    • Aggregating behavior of phenolic compounds - A source of false bioassay results'
    • Pohjala, L. and Tammela, P. (2012) Aggregating behavior of phenolic compounds-A source of false bioassay results' Molecules 17, 10774-10790
    • (2012) Molecules , vol.17 , pp. 10774-10790
    • Pohjala, L.1    Tammela, P.2
  • 19
    • 84869411678 scopus 로고    scopus 로고
    • Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor
    • Anderson, D. E., Kim, M. B., Moore, J. T., O'Brien, T. E., Sorto, N. A., Grove, C. I., Lackner, L. L., Ames, J. B., and Shaw, J. T. (2012) Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor ACS Chem. Biol. 7, 1918-1928
    • (2012) ACS Chem. Biol. , vol.7 , pp. 1918-1928
    • Anderson, D.E.1    Kim, M.B.2    Moore, J.T.3    Obrien, T.E.4    Sorto, N.A.5    Grove, C.I.6    Lackner, L.L.7    Ames, J.B.8    Shaw, J.T.9
  • 20
    • 81855226548 scopus 로고    scopus 로고
    • NSAID-based gamma-secretase modulators do not bind to the amyloid-beta polypeptide
    • Barrett, P. J., Sanders, C. R., Kaufman, S. A., Michelsen, K., and Jordan, J. B. (2011) NSAID-based gamma-secretase modulators do not bind to the amyloid-beta polypeptide Biochemistry 50, 10328-10342
    • (2011) Biochemistry , vol.50 , pp. 10328-10342
    • Barrett, P.J.1    Sanders, C.R.2    Kaufman, S.A.3    Michelsen, K.4    Jordan, J.B.5
  • 21
    • 39149130730 scopus 로고    scopus 로고
    • Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors
    • Giannetti, A. M., Koch, B. D., and Browner, M. F. (2008) Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors J. Med. Chem. 51, 574-80
    • (2008) J. Med. Chem. , vol.51 , pp. 574-580
    • Giannetti, A.M.1    Koch, B.D.2    Browner, M.F.3
  • 22
    • 77953689492 scopus 로고    scopus 로고
    • Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology
    • Thorne, N., Inglese, J., and Auld, D. S. (2010) Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology Chem. Biol. 17, 646-657
    • (2010) Chem. Biol. , vol.17 , pp. 646-657
    • Thorne, N.1    Inglese, J.2    Auld, D.S.3
  • 23
    • 84866974569 scopus 로고    scopus 로고
    • A coincidence reporter-gene system for high-throughput screening
    • Cheng, K. C. and Inglese, J. (2012) A coincidence reporter-gene system for high-throughput screening Nat. Methods 9, 937
    • (2012) Nat. Methods , vol.9 , pp. 937
    • Cheng, K.C.1    Inglese, J.2
  • 25
    • 15444366107 scopus 로고    scopus 로고
    • Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability
    • Frenkel, Y. V., Clark, A. D., Das, K., Wang, Y.-H., Lewi, P. J., Janssen, P. A. J., and Arnold, E. (2005) Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability J. Med. Chem. 48, 1974-1983
    • (2005) J. Med. Chem. , vol.48 , pp. 1974-1983
    • Frenkel, Y.V.1    Clark, A.D.2    Das, K.3    Wang, Y.-H.4    Lewi, P.J.5    Janssen, P.A.J.6    Arnold, E.7
  • 26
    • 77952733763 scopus 로고    scopus 로고
    • Colloid formation by drugs in simulated intestinal fluid
    • Doak, A. K., Wille, H., Prusiner, S. B., and Shoichet, B. K. (2010) Colloid formation by drugs in simulated intestinal fluid J. Med. Chem. 53, 4259-4265
    • (2010) J. Med. Chem. , vol.53 , pp. 4259-4265
    • Doak, A.K.1    Wille, H.2    Prusiner, S.B.3    Shoichet, B.K.4
  • 27
    • 84865256887 scopus 로고    scopus 로고
    • Colloidal aggregation affects the efficacy of anticancer drugs in cell culture
    • Owen, S. C., Doak, A. K., Wassam, P., Shoichet, M. S., and Shoichet, B. K. (2012) Colloidal aggregation affects the efficacy of anticancer drugs in cell culture ACS Chem. Biol. 7, 1429-1435
    • (2012) ACS Chem. Biol. , vol.7 , pp. 1429-1435
    • Owen, S.C.1    Doak, A.K.2    Wassam, P.3    Shoichet, M.S.4    Shoichet, B.K.5
  • 28
    • 84884244385 scopus 로고    scopus 로고
    • Monitoring drug self-aggregation and potential for promiscuity in off-target in vitro pharmacology screens by a practical NMR strategy
    • LaPlante, S. R., Aubry, N., Bolger, G., Bonneau, P., Carson, R., Coulombe, R., Sturino, C., and Beaulieu, P. L. (2013) Monitoring drug self-aggregation and potential for promiscuity in off-target in vitro pharmacology screens by a practical NMR strategy J. Med. Chem. 56, 7073-7083
    • (2013) J. Med. Chem. , vol.56 , pp. 7073-7083
    • Laplante, S.R.1    Aubry, N.2    Bolger, G.3    Bonneau, P.4    Carson, R.5    Coulombe, R.6    Sturino, C.7    Beaulieu, P.L.8
  • 31
    • 38749137769 scopus 로고    scopus 로고
    • Effect of chitosans and other excipients on the permeation of ketotifen, FITC-dextran, and rhodamine 123 through Caco-2 cells
    • Bejugam, N. K., Sou, M., Uddin, A. N., Gayakwad, S. G., and D'souza, M. J. (2008) Effect of chitosans and other excipients on the permeation of ketotifen, FITC-dextran, and rhodamine 123 through Caco-2 cells J. Bioact. Compat. Polym. 23, 187-202
    • (2008) J. Bioact. Compat. Polym. , vol.23 , pp. 187-202
    • Bejugam, N.K.1    Sou, M.2    Uddin, A.N.3    Gayakwad, S.G.4    Dsouza, M.J.5
  • 32
    • 84875776484 scopus 로고    scopus 로고
    • Liquid-liquid phase separation in highly supersaturated aqueous solutions of poorly water-soluble drugs: Implications for solubility enhancing formulations
    • Ilevbare, G. A. and Taylor, L. S. (2013) Liquid-liquid phase separation in highly supersaturated aqueous solutions of poorly water-soluble drugs: Implications for solubility enhancing formulations Cryst. Growth Des. 13, 1497-1509
    • (2013) Cryst. Growth Des. , vol.13 , pp. 1497-1509
    • Ilevbare, G.A.1    Taylor, L.S.2
  • 33
    • 84875733971 scopus 로고    scopus 로고
    • Colloidal aggregation causes inhibition of G protein-coupled receptors
    • Sassano, M. F., Doak, A. K., Roth, B. L., and Shoichet, B. K. (2013) Colloidal aggregation causes inhibition of G protein-coupled receptors J. Med. Chem. 56, 2406-2414
    • (2013) J. Med. Chem. , vol.56 , pp. 2406-2414
    • Sassano, M.F.1    Doak, A.K.2    Roth, B.L.3    Shoichet, B.K.4
  • 34
    • 18144386167 scopus 로고    scopus 로고
    • Mammalian lignans and genistein decrease the activities of aromatase and 17β-hydroxysteroid dehydrogenase in MCF-7 cells
    • Brooks, J. D. and Thompson, L. U. (2005) Mammalian lignans and genistein decrease the activities of aromatase and 17β-hydroxysteroid dehydrogenase in MCF-7 cells J. Steroid Biochem. Mol. Biol. 94, 461-467
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.94 , pp. 461-467
    • Brooks, J.D.1    Thompson, L.U.2
  • 35
    • 34548329748 scopus 로고    scopus 로고
    • Genistein-induced apoptosis of human breast cancer MCF-7 cells involves calpain-caspase and apoptosis signaling kinase 1-p38 mitogen-activated protein kinase activation cascades
    • Shim, H.-Y., Park, J.-H., Paik, H.-D., Nah, S.-Y., Kim, D. S. H. L., and Han, Y. S. (2007) Genistein-induced apoptosis of human breast cancer MCF-7 cells involves calpain-caspase and apoptosis signaling kinase 1-p38 mitogen-activated protein kinase activation cascades Anti-Cancer Drugs 18, 649-657
    • (2007) Anti-Cancer Drugs , vol.18 , pp. 649-657
    • Shim, H.-Y.1    Park, J.-H.2    Paik, H.-D.3    Nah, S.-Y.4    Kim, D.S.H.L.5    Han, Y.S.6
  • 37
    • 0000808698 scopus 로고
    • Thermodynamics of micellization of non-ionic detergents
    • Corkill, J. M., Goodman, J. F., and Harrold, S. P. (1964) Thermodynamics of micellization of non-ionic detergents Trans. Faraday Soc. 60, 202.
    • (1964) Trans. Faraday Soc. , vol.60 , pp. 202
    • Corkill, J.M.1    Goodman, J.F.2    Harrold, S.P.3
  • 39
    • 51149102710 scopus 로고    scopus 로고
    • Trypan blue exclusion test of cell viability
    • John Wiley & Sons, Inc. New York, NY
    • Strober, W. (2001) Trypan blue exclusion test of cell viability, in Current Protocols in Immunology, John Wiley & Sons, Inc., New York, NY.
    • (2001) Current Protocols in Immunology
    • Strober, W.1
  • 45
    • 0024663034 scopus 로고
    • Polymeric micelles - Their relaxation kinetics
    • Halperin, A. and Alexander, S. (1989) Polymeric micelles-their relaxation kinetics Macromolecules 22, 2403-2412
    • (1989) Macromolecules , vol.22 , pp. 2403-2412
    • Halperin, A.1    Alexander, S.2
  • 48
    • 0031800878 scopus 로고    scopus 로고
    • Effects of pluronic block copolymers on drug absorption in Caco-2 cell monolayers
    • Batrakova, E., Han, H.-Y., Alakhov, V., Miller, D., and Kabanov, A. (1998) Effects of pluronic block copolymers on drug absorption in Caco-2 cell monolayers Pharm. Res. 15, 850-855
    • (1998) Pharm. Res. , vol.15 , pp. 850-855
    • Batrakova, E.1    Han, H.-Y.2    Alakhov, V.3    Miller, D.4    Kabanov, A.5
  • 49
    • 0030915885 scopus 로고    scopus 로고
    • The effect of monomers and of micellar and vesicular forms of non-ionic surfactants (Solulan C24 and Solulan 16) on Caco-2 cell monolayers
    • Dimitrijevic, D., Lamandin, C., Uchegbu, I. F., Shaw, A. J., and Florence, A. T. (1997) The effect of monomers and of micellar and vesicular forms of non-ionic surfactants (Solulan C24 and Solulan 16) on Caco-2 cell monolayers J. Pharm. Pharmacol. 49, 611-616
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 611-616
    • Dimitrijevic, D.1    Lamandin, C.2    Uchegbu, I.F.3    Shaw, A.J.4    Florence, A.T.5
  • 50
    • 0242361285 scopus 로고    scopus 로고
    • Inhibitory action of ICI-182,780, an estrogen receptor antagonist, on BKCa channel activity in cultured endothelial cells of human coronary artery
    • Liu, Y.-C., Lo, Y.-C., Huang, C.-W., and Wu, S.-N. (2003) Inhibitory action of ICI-182,780, an estrogen receptor antagonist, on BKCa channel activity in cultured endothelial cells of human coronary artery Biochem. Pharmacol. 66, 2053-2063
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 2053-2063
    • Liu, Y.-C.1    Lo, Y.-C.2    Huang, C.-W.3    Wu, S.-N.4
  • 53
    • 84875678388 scopus 로고    scopus 로고
    • U-shape suppressive effect of phenol red on the epileptiform burst activity via activation of estrogen receptors in primary hippocampal culture
    • e60189
    • Liu, X., Chen, B., Chen, L., Ren, W.-T., Liu, J., Wang, G., Fan, W., Wang, X., and Wang, Y. (2013) U-shape suppressive effect of phenol red on the epileptiform burst activity via activation of estrogen receptors in primary hippocampal culture PLoS One 8 e60189
    • (2013) PLoS One , vol.8
    • Liu, X.1    Chen, B.2    Chen, L.3    Ren, W.-T.4    Liu, J.5    Wang, G.6    Fan, W.7    Wang, X.8    Wang, Y.9
  • 54
    • 80052143482 scopus 로고    scopus 로고
    • Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor gunction
    • Lee, T. H., Kim, K. H., Lee, S. O., Lee, K. R., Son, M., and Jin, M. (2011) Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor gunction J. Pharmacol. Exp. Ther. 338, 917-924
    • (2011) J. Pharmacol. Exp. Ther. , vol.338 , pp. 917-924
    • Lee, T.H.1    Kim, K.H.2    Lee, S.O.3    Lee, K.R.4    Son, M.5    Jin, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.