Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization

Journal of Virology

Volumn 88, Issue 8, 2014, Pages 4543-4557

  Kolawole, Abimbola O ^a   Li, Ming ^b   Xia, Chunsheng ^b   Fischer, Audrey E ^c   Giacobbi, Nicholas S ^d   Rippinger, Christine M ^a   Proescher, Jody B G ^c   Wu, Susan K ^c   Bessling, Seneca L ^c   Gamez, Monica ^a   Yu, Chenchen ^a   Zhang, Rebecca ^b   Mehoke, Thomas S ^c   Pipas, James M ^d   Wolfe, Joshua T ^c   Lin, Jeffrey S ^c   Feldman, Andrew B ^c   Smith, Thomas J ^b   Wobus, Christiane E ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b DONALD DANFORTH PLANT SCIENCE CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; CELL CULTURE; CONTROLLED STUDY; HEAVY CHAIN; HUMAN; LIGHT CHAIN; MOUSE; NONHUMAN; NOROVIRUS; NOROVIRUS INFECTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; STRUCTURE ANALYSIS; VIRUS CAPSID; VIRUS MUTATION; VIRUS NEUTRALIZATION; VIRUS STRAIN;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CALICIVIRIDAE INFECTIONS; CAPSID PROTEINS; CELL LINE; HUMANS; IMMUNE EVASION; MICE; MICE, KNOCKOUT; NEUTRALIZATION TESTS; NOROVIRUS;

EID: 84896934991     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03685-13     Document Type: Article

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