Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity

Journal of Virology

Volumn 88, Issue 8, 2014, Pages 4403-4413

  Schotte, Lise ^a   Strauss, Mike ^b   Thys, Bert ^a   Halewyck, Hadewych ^a   Filman, David J ^b   Bostina, Mihnea ^c,d   Hogle, James M ^b   Rombaut, Bart ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ARILDONE; NANOBODY; PIRODAVIR; PVSP19B ANTIBODY; PVSP29F ANTIBODY; PVSP6A ANTIBODY; PVSS21E ANTIBODY; PVSS8A ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY COMPLEX; ANTIPOLIOVIRAL ACTIVITY; ARTICLE; BINDING SITE; CAPSID STABILIZATION; CELL ADHESION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; DRUG ACTIVITY; DRUG MECHANISM; HELA CELL; IN VITRO STUDY; NONHUMAN; POLIOMYELITIS VIRUS 1; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; THERMOSTABILITY; VIRUS ATTACHMENT; VIRUS CAPSID; VIRUS ENTRY; VIRUS INACTIVATION; VIRUS PARTICLE; VIRUS REPLICATION; VIRUS UNCOATING;

ANTIBODIES, VIRAL; ANTIVIRAL AGENTS; CAPSID; CAPSID PROTEINS; CELL LINE; HUMANS; POLIOMYELITIS; POLIOVIRUS; SINGLE-DOMAIN ANTIBODIES; VIRUS REPLICATION; VIRUS UNCOATING;

EID: 84896920110     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03402-13     Document Type: Article

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