Low or high doses of cefquinome targeting low or high bacterial inocula cure Klebsiella pneumoniae lung infections but differentially impact the levels of antibiotic resistance in fecal flora

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 3, 2014, Pages 1744-1748

  Vasseur, Maleck V ^a,b,c   Laurentie, Michel ^c   Rolland, Jean Guy ^c   Perrin Guyomard, Agnès ^c   Henri, Jérôme ^c   Ferran, Aude A ^a,b   Toutain, Pierre Louis ^a,b   Bousquet Mélou, Alain ^a,b  

^a TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c FRENCH AGENCY FOR FOOD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE CTX M; CEFQUINOME; COBACTAN; EXTENDED SPECTRUM BETA LACTAMASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; AREA UNDER THE CURVE; ARTICLE; BACTERIAL COUNT; COLONY FORMING UNIT; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG MEGADOSE; ESCHERICHIA COLI; FECES MICROFLORA; GERMFREE ANIMAL; INTESTINE FLORA; KLEBSIELLA PNEUMONIAE INFECTION; LOW DRUG DOSE; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PATHOGEN LOAD; PNEUMONIA; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL LOAD; CEPHALOSPORINS; DRUG RESISTANCE, BACTERIAL; FECES; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; PNEUMONIA, BACTERIAL; RATS;

EID: 84896858986     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02135-13     Document Type: Article

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