메뉴 건너뛰기




Volumn 6, Issue 2, 2014, Pages 74-77

The Prostate Health Index: A new test for the detection of prostate cancer

Author keywords

free PSA; PHI; prognosis; prostate cancer; prostate health index; PSA; screening

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

EID: 84896795915     PISSN: 17562872     EISSN: 17562880     Source Type: Journal    
DOI: 10.1177/1756287213513488     Document Type: Review
Times cited : (144)

References (23)
  • 1
    • 84993809060 scopus 로고    scopus 로고
    • Cancer facts & figures 2013 [online]
    • Atlanta, GA: American Cancer Society,. Available at:, accessed 1 August 2013
    • American Cancer Society (ACS) (2013) Cancer facts & figures 2013 [online]. Atlanta, GA: American Cancer Society. Available at: http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-036845.pdf (accessed 1 August 2013).
    • (2013)
  • 2
    • 0242692670 scopus 로고    scopus 로고
    • Serum pro prostate specific antigen improves cancer detection compared to free and complexed prostate specific antigen in men with prostate specific antigen 2 to 4 ng/ml
    • Catalona W. Bartsch G. Rittenhouse H. Evans C. Linton H. Amirkhan A. (2003) Serum pro prostate specific antigen improves cancer detection compared to free and complexed prostate specific antigen in men with prostate specific antigen 2 to 4 ng/ml. J Urol 170: 2181–2185.
    • (2003) J Urol , vol.170 , pp. 2181-2185
    • Catalona, W.1    Bartsch, G.2    Rittenhouse, H.3    Evans, C.4    Linton, H.5    Amirkhan, A.6
  • 3
    • 79953777963 scopus 로고    scopus 로고
    • A multicenter study of [-2]pro-prostate specific antigen combined with prostate specific antigen and free prostate specific antigen for prostate cancer detection in the 2.0 to 10.0 ng/ml prostate specific antigen range
    • Catalona W. Partin A. Sanda M. Wei J. Klee G. Bangma C. (2011) A multicenter study of [-2]pro-prostate specific antigen combined with prostate specific antigen and free prostate specific antigen for prostate cancer detection in the 2.0 to 10.0 ng/ml prostate specific antigen range. J Urol 185: 1650–1655.
    • (2011) J Urol , vol.185 , pp. 1650-1655
    • Catalona, W.1    Partin, A.2    Sanda, M.3    Wei, J.4    Klee, G.5    Bangma, C.6
  • 4
    • 84879832558 scopus 로고    scopus 로고
    • Prostate Health Index (PHI) and Prostate Cancer Antigen 3 (PCA3) significantly improve prostate cancer detection at initial biopsy in a total PSA range of 2–10 ng/ml
    • Ferro M. Bruzzese D. Perdona S. Marino A. Mazzarella C. Perruolo G. (2013) Prostate Health Index (PHI) and Prostate Cancer Antigen 3 (PCA3) significantly improve prostate cancer detection at initial biopsy in a total PSA range of 2–10 ng/ml. PLoS One 8: e67687.
    • (2013) PLoS One , vol.8 , pp. e67687
    • Ferro, M.1    Bruzzese, D.2    Perdona, S.3    Marino, A.4    Mazzarella, C.5    Perruolo, G.6
  • 5
    • 84879876700 scopus 로고    scopus 로고
    • Clinical performance of serum prostate-specific antigen isoform [-2]proPSA (p2PSA) and its derivatives, %p2PSA and the prostate health index (PHI), in men with a family history of prostate cancer: results from a multicentre European study, the PROMEtheuS project
    • Lazzeri M. Haese A. Abrate A. de la Taille A. Redorta J. McNicholas T. (2013a) Clinical performance of serum prostate-specific antigen isoform [-2]proPSA (p2PSA) and its derivatives, %p2PSA and the prostate health index (PHI), in men with a family history of prostate cancer: results from a multicentre European study, the PROMEtheuS project. BJU Int 112: 313–321.
    • (2013) BJU Int , vol.112 , pp. 313-321
    • Lazzeri, M.1    Haese, A.2    Abrate, A.3    de la Taille, A.4    Redorta, J.5    McNicholas, T.6
  • 6
    • 84876473108 scopus 로고    scopus 로고
    • Serum isoform [-2]proPSA derivatives significantly improve prediction of prostate cancer at initial biopsy in a total PSA range of 2–10 ng/ml: a multicentric European study
    • Lazzeri M. Haese A. de la Taille A. Palou Redorta J. McNicholas T. Lughezzani G. (2013b) Serum isoform [-2]proPSA derivatives significantly improve prediction of prostate cancer at initial biopsy in a total PSA range of 2–10 ng/ml: a multicentric European study. Eur Urol 63: 986–994.
    • (2013) Eur Urol , vol.63 , pp. 986-994
    • Lazzeri, M.1    Haese, A.2    de la Taille, A.3    Palou Redorta, J.4    McNicholas, T.5    Lughezzani, G.6
  • 7
    • 77949277570 scopus 로고    scopus 로고
    • [-2]Proenzyme prostate specific antigen is more accurate than total and free prostate specific antigen in differentiating prostate cancer from benign disease in a prospective prostate cancer screening study
    • Le B. Griffin C. Loeb S. Carvalhal G. Kan D. Baumann N. (2010) [-2]Proenzyme prostate specific antigen is more accurate than total and free prostate specific antigen in differentiating prostate cancer from benign disease in a prospective prostate cancer screening study. J Urol 183: 1355–1359.
    • (2010) J Urol , vol.183 , pp. 1355-1359
    • Le, B.1    Griffin, C.2    Loeb, S.3    Carvalhal, G.4    Kan, D.5    Baumann, N.6
  • 8
    • 0026077430 scopus 로고
    • Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin
    • Lilja H. Christensson A. Dahlen U. Matikainen M. Nilsson O. Pettersson K. (1991) Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin. Clin Chem 37: 1618–1625.
    • (1991) Clin Chem , vol.37 , pp. 1618-1625
    • Lilja, H.1    Christensson, A.2    Dahlen, U.3    Matikainen, M.4    Nilsson, O.5    Pettersson, K.6
  • 9
    • 84873739031 scopus 로고    scopus 로고
    • Is repeat prostate biopsy associated with a greater risk of hospitalization? Data from SEER-Medicare
    • Loeb S. Carter H. Berndt S. Ricker W. Schaeffer E. (2012) Is repeat prostate biopsy associated with a greater risk of hospitalization? Data from SEER-Medicare. J Urol 189: 867–870.
    • (2012) J Urol , vol.189 , pp. 867-870
    • Loeb, S.1    Carter, H.2    Berndt, S.3    Ricker, W.4    Schaeffer, E.5
  • 10
    • 84876287137 scopus 로고    scopus 로고
    • Prospective multicenter evaluation of the Beckman Coulter Prostate Health Index using WHO calibration
    • Loeb S. Sokoll L. Broyles D. Bangma C. van Schaik R. Klee G. (2013) Prospective multicenter evaluation of the Beckman Coulter Prostate Health Index using WHO calibration. J Urol 189: 1702–1706.
    • (2013) J Urol , vol.189 , pp. 1702-1706
    • Loeb, S.1    Sokoll, L.2    Broyles, D.3    Bangma, C.4    van Schaik, R.5    Klee, G.6
  • 11
    • 2642583188 scopus 로고    scopus 로고
    • Proenzyme forms of prostate-specific antigen in serum improve the detection of prostate cancer
    • Mikolajczyk S. Catalona W. Evans C. Linton H. Millar L. Marker K. (2004) Proenzyme forms of prostate-specific antigen in serum improve the detection of prostate cancer. Clin Chem 50: 1017–1025.
    • (2004) Clin Chem , vol.50 , pp. 1017-1025
    • Mikolajczyk, S.1    Catalona, W.2    Evans, C.3    Linton, H.4    Millar, L.5    Marker, K.6
  • 12
    • 78650642291 scopus 로고    scopus 로고
    • Diffusion-weighted magnetic resonance imaging for monitoring prostate cancer progression in patients managed by active surveillance
    • Morgan V. Riches S. Thomas K. Vanas N. Parker C. Giles S. (2011) Diffusion-weighted magnetic resonance imaging for monitoring prostate cancer progression in patients managed by active surveillance. Br J Radiol 84: 31–37.
    • (2011) Br J Radiol , vol.84 , pp. 31-37
    • Morgan, V.1    Riches, S.2    Thomas, K.3    Vanas, N.4    Parker, C.5    Giles, S.6
  • 13
    • 84890534361 scopus 로고    scopus 로고
    • The Melbourne Consensus Statement on Prostate Cancer Testing [online], BJU International
    • Available at:, accessed 15 September 2013
    • Murphy D. Costello T. Walsh P. Ahlering T. Cataolona W. Santor O. (2013) The Melbourne Consensus Statement on Prostate Cancer Testing [online], BJU International. Available at: http://www.bjuinternational.com/bjui-blog/the-melbourne-consensus-statement-on-prostate-cancer-testing/ (accessed 15 September 2013).
    • (2013)
    • Murphy, D.1    Costello, T.2    Walsh, P.3    Ahlering, T.4    Cataolona, W.5    Santor, O.6
  • 14
    • 77956396162 scopus 로고    scopus 로고
    • Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program
    • Ross A. Loeb S. Landis P. Partin A. Epstein J. Kettermann A. (2010) Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program. J Clin Oncol 28: 2810–2816.
    • (2010) J Clin Oncol , vol.28 , pp. 2810-2816
    • Ross, A.1    Loeb, S.2    Landis, P.3    Partin, A.4    Epstein, J.5    Kettermann, A.6
  • 15
    • 84943319825 scopus 로고    scopus 로고
    • Evaluation of the Prostate Health Index (PHI) for improving prostate cancer detection and identification of clinically significant prostate cancer in the 4 to 10 ng/mL PSA range
    • In:, Proceedings of American Urological Association Annual Meeting, San Diego.
    • Sanda M. Wei J. Broyles D. Shin S. Partin A. Klee G. (2013) Evaluation of the Prostate Health Index (PHI) for improving prostate cancer detection and identification of clinically significant prostate cancer in the 4 to 10 ng/mL PSA range. In: Proceedings of American Urological Association Annual Meeting, San Diego.
    • (2013)
    • Sanda, M.1    Wei, J.2    Broyles, D.3    Shin, S.4    Partin, A.5    Klee, G.6
  • 16
    • 84880046442 scopus 로고    scopus 로고
    • Head-to-head comparison of Prostate Health Index and urinary PCA3 for predicting cancer at initial or repeat niopsy
    • Scattoni V. Lazzeri M. Lughezzani G. De Luca S. Passera R. Bollito E. (2013) Head-to-head comparison of Prostate Health Index and urinary PCA3 for predicting cancer at initial or repeat niopsy. J Urol 190: 496–501.
    • (2013) J Urol , vol.190 , pp. 496-501
    • Scattoni, V.1    Lazzeri, M.2    Lughezzani, G.3    De Luca, S.4    Passera, R.5    Bollito, E.6
  • 18
    • 77952082471 scopus 로고    scopus 로고
    • A prospective, multicenter, National Cancer Institute Early Detection Research Network study of [-2]proPSA: improving prostate cancer detection and correlating with cancer aggressiveness
    • Sokoll L. Sanda M. Feng Z. Kagan J. Mizrahi I. Broyles D. (2010) A prospective, multicenter, National Cancer Institute Early Detection Research Network study of [-2]proPSA: improving prostate cancer detection and correlating with cancer aggressiveness. Cancer Epidemiol Biomarkers Prev 19: 1193–1200.
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 1193-1200
    • Sokoll, L.1    Sanda, M.2    Feng, Z.3    Kagan, J.4    Mizrahi, I.5    Broyles, D.6
  • 19
    • 84856829087 scopus 로고    scopus 로고
    • A pilot study evaluating serum pro-prostate-specific antigen in patients with rising PSA following radical prostatectomy
    • Sottile A. Ortega C. Berruti A. Mangioni M. Saponaro S. Polo A. (2012) A pilot study evaluating serum pro-prostate-specific antigen in patients with rising PSA following radical prostatectomy. Oncol Lett 3: 819–824.
    • (2012) Oncol Lett , vol.3 , pp. 819-824
    • Sottile, A.1    Ortega, C.2    Berruti, A.3    Mangioni, M.4    Saponaro, S.5    Polo, A.6
  • 20
    • 0026027671 scopus 로고
    • A complex between prostate-specific antigen and alpha 1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: assay of the complex improves clinical sensitivity for cancer
    • Stenman U. Leinonen J. Alfthan H. Rannikko S. Tuhkanen K. Alfthan O. (1991) A complex between prostate-specific antigen and alpha 1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: assay of the complex improves clinical sensitivity for cancer. Cancer Res 51: 222–226.
    • (1991) Cancer Res , vol.51 , pp. 222-226
    • Stenman, U.1    Leinonen, J.2    Alfthan, H.3    Rannikko, S.4    Tuhkanen, K.5    Alfthan, O.6
  • 21
    • 84872033007 scopus 로고    scopus 로고
    • Comparative assessment of urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion with the serum [-2]proprostate-specific antigen-based prostate health index for detection of prostate cancer
    • Stephan C. Jung K. Semjonow A. Schulze-Forster K. Cammann H. Hu X. (2013) Comparative assessment of urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion with the serum [-2]proprostate-specific antigen-based prostate health index for detection of prostate cancer. Clin Chem 59: 280–88.
    • (2013) Clin Chem , vol.59 , pp. 280-288
    • Stephan, C.1    Jung, K.2    Semjonow, A.3    Schulze-Forster, K.4    Cammann, H.5    Hu, X.6
  • 22
    • 84866090485 scopus 로고    scopus 로고
    • Association of [-2]proPSA with biopsy reclassification during active surveillance for prostate cancer
    • Tosoian J. Loeb S. Feng Z. Isharwal S. Landis P. Elliot D. (2012) Association of [-2]proPSA with biopsy reclassification during active surveillance for prostate cancer. J Urol 188: 1131–1136.
    • (2012) J Urol , vol.188 , pp. 1131-1136
    • Tosoian, J.1    Loeb, S.2    Feng, Z.3    Isharwal, S.4    Landis, P.5    Elliot, D.6
  • 23
    • 73749086977 scopus 로고    scopus 로고
    • Accuracy of PCA3 measurement in predicting short-term biopsy progression in an active surveillance program
    • Tosoian J. Loeb S. Kettermann A. Landis P. Elliot D. Epstein J. (2010) Accuracy of PCA3 measurement in predicting short-term biopsy progression in an active surveillance program. J Urol 183: 534–538.
    • (2010) J Urol , vol.183 , pp. 534-538
    • Tosoian, J.1    Loeb, S.2    Kettermann, A.3    Landis, P.4    Elliot, D.5    Epstein, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.