Peptide-conjugated phosphorodiamidate morpholino oligomers: A new strategy for tackling antibiotic resistance

Therapeutic Delivery

Volumn 5, Issue 3, 2014, Pages 243-245

  Geller, Bruce L ^a   Greenberg, David E ^b  

^a OREGON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Acinetobacter baumannii; Acinetobacter lwoffii; antibiotic resistance; antisense; MIC; morpholino oligomer; mouse; peptide conjugated phosphorodiamidate morpholino oligomers; respiratory infection

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; PEPTIDE; PEPTIDE CONJUGATED PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ACINETOBACTER BAUMANNII; ACINETOBACTER LWOFFII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; ANTISENSE THERAPY; BACTEREMIA; BACTERIAL GENE; BACTERIAL PNEUMONIA; BACTERIAL TRANSMISSION; BACTERIAL VIRULENCE; BIOFILM; BURKHOLDERIA CEPACIA COMPLEX; EDITORIAL; ESSENTIAL GENE; GENE TARGETING; HUMAN; IN VITRO STUDY; LUNG INFECTION; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RNA BINDING; SEPSIS; SPONTANEOUS MUTATION; URINARY TRACT INFECTION; VENTILATOR ASSOCIATED PNEUMONIA; WOUND INFECTION;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MORPHOLINOS; PEPTIDES; RNA, BACTERIAL; RNA, MESSENGER;

EID: 84896740974     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.13.145     Document Type: Editorial

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