SCOPUS 정보 검색 플랫폼

Volumn 22, Issue 5, 2014, Pages 1596-1607

Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists

(6) Liu, Peng a Xu, Xing b Chen, Lili b Ma, Lei a Shen, Xu b Hu, Lihong a,b

a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (China)

b SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

Author keywords

FXR antagonist; Hydroxyacetophenone derivatives; Non steroidal; SAR study

Indexed keywords

1 [2 (BENZYLOXY) 5 ETHYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [2 (CYCLOHEXYLMETHOXY) 5 ETHYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [2 (CYCLOPENTYLOXY) 5 ETHYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY] 5 PROPYLPHENYL]ETHANONE; 1 [2 HYDROXY 5 ISOBUTYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [5 BUTYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [5 ETHYL 2 HYDROXY 4 [[4 METHYL 4 (1H TETRAZOL 5 YL)PENTYL]OXY]PHENYL]ETHANONE; 1 [5 ETHYL 2 HYDROXY 4 [[5 METHYL 4 (1H TETRAZOL 5 YL)HEXYL]OXY]PHENYL]ETHANONE; 1 [5 ETHYL 2 HYDROXY 4 [[6 METHYL 4 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]PROPAN 1 ONE; 1 [5 ETHYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL] 2 METHYLPROPAN 1 ONE; 1 [5 ETHYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL](PHENYL)METHANONE; 1 [5 ETHYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]HEPTAN 1 ONE; 1 [5 ETHYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]PENTAN 1 ONE; 1 [5 ETHYL 2 HYDROXY 4 [[7 METHYL 4 (1H TETRAZOL 5 YL)OCTYL]OXY]PHENYL]ETHANONE; 1 [5 ETHYL 2 METHOXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; 1 [5 ETHYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY] 2 (1 PHENYLETHOXY)PHENYL]ETHANONE; 1 [5 ETHYL 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY] 2 [(3 METHYLBENZYL)OXY]PHENYL]ETHANONE; 1 [5 HEXYL 2 HYDROXY 4 [[6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYL]OXY]PHENYL]ETHANONE; AROMATIC COMPOUND; CARBON; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR ANTAGONIST; HYDROXYACETOPHENONE DERIVATIVE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; 4-HYDROXYACETOPHENONE; ACETOPHENONE DERIVATIVE; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RESEARCH; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING; IC 50; LIPOPHILICITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN;

ACETOPHENONES; HUMANS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896729024 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.01.032 Document Type: Article

Times cited : (20)

References (35)

1
- 0029046931
- B.M. Forman, E. Goode, J. Chen, A.E. Oro, D.J. Bradley, T. Perlmann, D.J. Noonan, L.T. Burka, T. McMorris, W.W. Lamph, R.M. Evans, and C. Weinberger Cell 81 1995 687
- (1995) Cell , vol.81 , pp. 687
- Forman, B.M.¹ Goode, E.² Chen, J.³ Oro, A.E.⁴ Bradley, D.J.⁵ Perlmann, T.⁶ Noonan, D.J.⁷ Burka, L.T.⁸ McMorris, T.⁹ Lamph, W.W.¹⁰ Evans, R.M.¹¹ Weinberger, C.¹²

2
- 0033591387
- D.J. Parks, S.G. Blanchard, R.K. Bledsoe, G. Chandra, T.G. Consler, S.A. Kliewer, J.B. Stimmel, T.M. Willson, A.M. Zavacki, D.D. Moore, and J.M. Lehmann Science 284 1999 1365
- (1999) Science , vol.284 , pp. 1365
- Parks, D.J.¹ Blanchard, S.G.² Bledsoe, R.K.³ Chandra, G.⁴ Consler, T.G.⁵ Kliewer, S.A.⁶ Stimmel, J.B.⁷ Willson, T.M.⁸ Zavacki, A.M.⁹ Moore, D.D.¹⁰ Lehmann, J.M.¹¹

3
- 70349430938
- J.Y.L. Chiang J. Lipid Res. 50 2009 1955
- (2009) J. Lipid Res. , vol.50 , pp. 1955
- Chiang, J.Y.L.¹

4
- 58249110568
- P. Lefebvre, B. Cariou, F. Lien, F. Kuipers, and B. Staels Physiol. Rev. 89 2009 147
- (2009) Physiol. Rev. , vol.89 , pp. 147
- Lefebvre, P.¹ Cariou, B.² Lien, F.³ Kuipers, F.⁴ Staels, B.⁵

5
- 79960617989
- S. Fiorucci, S. Cipriani, A. Mencarelli, F. Baldelli, G. Bifulco, and A. Zampella Mini-Rev. Med. Chem. 11 2011 753
- (2011) Mini-Rev. Med. Chem. , vol.11 , pp. 753
- Fiorucci, S.¹ Cipriani, S.² Mencarelli, A.³ Baldelli, F.⁴ Bifulco, G.⁵ Zampella, A.⁶

6
- 82455164172
- J.S. Teodoro, A.P. Rolo, and C.M. Palmeira Trends Endocrinol. Metab. 22 2011 458
- (2011) Trends Endocrinol. Metab. , vol.22 , pp. 458
- Teodoro, J.S.¹ Rolo, A.P.² Palmeira, C.M.³

7
- 85047684249
- C.R. Pullinger, C. Eng, G. Salen, S. Shefer, A.K. Batta, S.K. Erickson, A. Verhagen, C.R. Rivera, S.J. Mulvihill, M.J. Malloy, and J.P. Kane J. Clin. Invest. 110 2002 109
- (2002) J. Clin. Invest. , vol.110 , pp. 109
- Pullinger, C.R.¹ Eng, C.² Salen, G.³ Shefer, S.⁴ Batta, A.K.⁵ Erickson, S.K.⁶ Verhagen, A.⁷ Rivera, C.R.⁸ Mulvihill, S.J.⁹ Malloy, M.J.¹⁰ Kane, J.P.¹¹

8
- 84881457500
- S. Seok, D. Kanamaluru, Z. Xiao, D. Ryerson, S.-E. Choi, K. Suino-Powell, H.E. Xu, T.D. Veenstra, and J.K. Kemper J. Biol. Chem. 288 2013 23252
- (2013) J. Biol. Chem. , vol.288 , pp. 23252
- Seok, S.¹ Kanamaluru, D.² Xiao, Z.³ Ryerson, D.⁴ Choi, S.-E.⁵ Suino-Powell, K.⁶ Xu, H.E.⁷ Veenstra, T.D.⁸ Kemper, J.K.⁹

9
- 0035800772
- M. Ananthanarayanan, N. Balasubramanian, M. Makishima, D.J. Mangelsdorf, and F.J. Suchy J. Biol. Chem. 276 2001 28857
- (2001) J. Biol. Chem. , vol.276 , pp. 28857
- Ananthanarayanan, M.¹ Balasubramanian, N.² Makishima, M.³ Mangelsdorf, D.J.⁴ Suchy, F.J.⁵

10
- 0034950514
- L.A. Denson, E. Sturm, W. Echevarria, T.L. Zimmerman, M. Makishima, D.J. Mangelsdorf, and S.J. Karpen Gastroenterology 121 2001 140
- (2001) Gastroenterology , vol.121 , pp. 140
- Denson, L.A.¹ Sturm, E.² Echevarria, W.³ Zimmerman, T.L.⁴ Makishima, M.⁵ Mangelsdorf, D.J.⁶ Karpen, S.J.⁷

11
- 84861088470
- S. Fiorucci, A. Mencarelli, E. Distrutti, and A. Zampella Future Med. Chem. 4 2012 877
- (2012) Future Med. Chem. , vol.4 , pp. 877
- Fiorucci, S.¹ Mencarelli, A.² Distrutti, E.³ Zampella, A.⁴

12
- 84861892108
- D. Merk, D. Steinhilber, and M. Schubert-Zsilavecz Future Med. Chem. 4 2012 1015
- (2012) Future Med. Chem. , vol.4 , pp. 1015
- Merk, D.¹ Steinhilber, D.² Schubert-Zsilavecz, M.³

13
- 0037101810
- R. Pellicciari, S. Fiorucci, E. Camaioni, C. Clerici, G. Costantino, P.R. Maloney, A. Morelli, D.J. Parks, and T.M. Willson J. Med. Chem. 45 2002 3569
- (2002) J. Med. Chem. , vol.45 , pp. 3569
- Pellicciari, R.¹ Fiorucci, S.² Camaioni, E.³ Clerici, C.⁴ Costantino, G.⁵ Maloney, P.R.⁶ Morelli, A.⁷ Parks, D.J.⁸ Willson, T.M.⁹

14
- 77649229482
- J.T. Lundquist, D.C. Harnish, C.Y. Kim, J.F. Mehlmann, R.J. Unwalla, K.M. Phipps, M.L. Crawley, T. Commons, D.M. Green, W. Xu, W.-T. Hum, J.E. Eta, I. Feingold, V. Patel, M.J. Evans, K.D. Lai, L. Borges-Marcucci, P.E. Mahaney, and J.E. Wrobel J. Med. Chem. 53 2010 1774
- (2010) J. Med. Chem. , vol.53 , pp. 1774
- Lundquist, J.T.¹ Harnish, D.C.² Kim, C.Y.³ Mehlmann, J.F.⁴ Unwalla, R.J.⁵ Phipps, K.M.⁶ Crawley, M.L.⁷ Commons, T.⁸ Green, D.M.⁹ Xu, W.¹⁰ Hum, W.-T.¹¹ Eta, J.E.¹² Feingold, I.¹³ Patel, V.¹⁴ Evans, M.J.¹⁵ Lai, K.D.¹⁶ Borges-Marcucci, L.¹⁷ Mahaney, P.E.¹⁸ Wrobel, J.E.¹⁹

15
- 64349115048
- B. Flatt, R. Martin, T.-L. Wang, P. Mahaney, B. Murphy, X.-H. Gu, P. Foster, J. Li, P. Pircher, M. Petrowski, I. Schulman, S. Westin, J. Wrobel, G. Yan, E. Bischoff, C. Daige, and R. Mohan J. Med. Chem. 52 2009 904
- (2009) J. Med. Chem. , vol.52 , pp. 904
- Flatt, B.¹ Martin, R.² Wang, T.-L.³ Mahaney, P.⁴ Murphy, B.⁵ Gu, X.-H.⁶ Foster, P.⁷ Li, J.⁸ Pircher, P.⁹ Petrowski, M.¹⁰ Schulman, I.¹¹ Westin, S.¹² Wrobel, J.¹³ Yan, G.¹⁴ Bischoff, E.¹⁵ Daige, C.¹⁶ Mohan, R.¹⁷

16
- 68949125075
- J.F. Mehlmann, M.L. Crawley, J.T. Lundquist Iv, R.J. Unwalla, D.C. Harnish, M.J. Evans, C.Y. Kim, J.E. Wrobel, and P.E. Mahaney Bioorg. Med. Chem. Lett. 19 2009 5289
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 5289
- Mehlmann, J.F.¹ Crawley, M.L.² Lundquist Iv, J.T.³ Unwalla, R.J.⁴ Harnish, D.C.⁵ Evans, M.J.⁶ Kim, C.Y.⁷ Wrobel, J.E.⁸ Mahaney, P.E.⁹

17
- 79851510529
- H.G.F. Richter, G.M. Benson, K.H. Bleicher, D. Blum, E. Chaput, N. Clemann, S. Feng, C. Gardes, U. Grether, P. Hartman, B. Kuhn, R.E. Martin, J.M. Plancher, M.G. Rudolph, F. Schuler, and S. Taylor Bioorg. Med. Chem. Lett. 21 2011 1134
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 1134
- Richter, H.G.F.¹ Benson, G.M.² Bleicher, K.H.³ Blum, D.⁴ Chaput, E.⁵ Clemann, N.⁶ Feng, S.⁷ Gardes, C.⁸ Grether, U.⁹ Hartman, P.¹⁰ Kuhn, B.¹¹ Martin, R.E.¹² Plancher, J.M.¹³ Rudolph, M.G.¹⁴ Schuler, F.¹⁵ Taylor, S.¹⁶

18
- 64249153603
- S. Feng, M. Yang, Z. Zhang, Z. Wang, D. Hong, H. Richter, G.M. Benson, K. Bleicher, U. Grether, R.E. Martin, J.-M. Plancher, B. Kuhn, M.G. Rudolph, and L. Chen Bioorg. Med. Chem. Lett. 19 2009 2595
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2595
- Feng, S.¹ Yang, M.² Zhang, Z.³ Wang, Z.⁴ Hong, D.⁵ Richter, H.⁶ Benson, G.M.⁷ Bleicher, K.⁸ Grether, U.⁹ Martin, R.E.¹⁰ Plancher, J.-M.¹¹ Kuhn, B.¹² Rudolph, M.G.¹³ Chen, L.¹⁴

19
- 79960598880
- S. Fiorucci, C. Clerici, D. Castellani, G. Sabatino, E. Antonelli, B. Goodwin, T.M. Willson, K.D. Setchell, A. Morelli, and R. Pellicciari Gastroenterology 124 2003 A698
- (2003) Gastroenterology , vol.124 , pp. 698
- Fiorucci, S.¹ Clerici, C.² Castellani, D.³ Sabatino, G.⁴ Antonelli, E.⁵ Goodwin, B.⁶ Willson, T.M.⁷ Setchell, K.D.⁸ Morelli, A.⁹ Pellicciari, R.¹⁰

20
- 77955415168
- D. Shapiro, B. March, L. Eliot, R. duBois, and M. Pruzanski Hepatology 50 2009 770A
- (2009) Hepatology , vol.50
- Shapiro, D.¹ March, B.² Eliot, L.³ Dubois, R.⁴ Pruzanski, M.⁵

21
- 84856084764
- B. Renga, A. Mencarelli, C. D'Amore, S. Cipriani, M.V. D'Auria, V. Sepe, M.G. Chini, M.C. Monti, G. Bifulco, A. Zampella, and S. Fiorucci PLoS One 7 2012 e30443
- (2012) PLoS One , vol.7 , pp. 30443
- Renga, B.¹ Mencarelli, A.² D'Amore, C.³ Cipriani, S.⁴ D'Auria, M.V.⁵ Sepe, V.⁶ Chini, M.G.⁷ Monti, M.C.⁸ Bifulco, G.⁹ Zampella, A.¹⁰ Fiorucci, S.¹¹

22
- 84866903943
- H. Huang, Y. Yu, Z. Gao, Y. Zhang, C. Li, X. Xu, H. Jin, W. Yan, R. Ma, J. Zhu, X. Shen, H. Jiang, L. Chen, and J. Li J. Med. Chem. 55 2012 7037
- (2012) J. Med. Chem. , vol.55 , pp. 7037
- Huang, H.¹ Yu, Y.² Gao, Z.³ Zhang, Y.⁴ Li, C.⁵ Xu, X.⁶ Jin, H.⁷ Yan, W.⁸ Ma, R.⁹ Zhu, J.¹⁰ Shen, X.¹¹ Jiang, H.¹² Chen, L.¹³ Li, J.¹⁴

23
- 0003295132
- J. Cui, L. Huang, A. Zhao, J.-L. Lew, J. Yu, S. Sahoo, P.T. Meinke, I. Royo, F. Pelaez, and S.D. Wright J. Biol. Chem. 278 2003 10214
- (2003) J. Biol. Chem. , vol.278 , pp. 10214
- Cui, J.¹ Huang, L.² Zhao, A.³ Lew, J.-L.⁴ Yu, J.⁵ Sahoo, S.⁶ Meinke, P.T.⁷ Royo, I.⁸ Pelaez, F.⁹ Wright, S.D.¹⁰

24
- 20144369215
- T.P. Burris, C. Montrose, K.A. Houck, H.E. Osborne, W.P. Bocchinfuso, B.C. Yaden, C.C. Cheng, R.W. Zink, R.J. Barr, C.D. Hepler, V. Krishnan, H.A. Bullock, L.L. Burris, R.J. Galvin, K. Bramlett, and K.R. Stayrook Mol. Pharmacol. 67 2005 948
- (2005) Mol. Pharmacol. , vol.67 , pp. 948
- Burris, T.P.¹ Montrose, C.² Houck, K.A.³ Osborne, H.E.⁴ Bocchinfuso, W.P.⁵ Yaden, B.C.⁶ Cheng, C.C.⁷ Zink, R.W.⁸ Barr, R.J.⁹ Hepler, C.D.¹⁰ Krishnan, V.¹¹ Bullock, H.A.¹² Burris, L.L.¹³ Galvin, R.J.¹⁴ Bramlett, K.¹⁵ Stayrook, K.R.¹⁶

25
- 0037205046
- N.L. Urizar, A.B. Liverman, D.N.T. Dodds, F.V. Silva, P. Ordentlich, Y. Yan, F.J. Gonzalez, R.A. Heyman, D.J. Mangelsdorf, and D.D. Moore Science 296 2002 1703
- (2002) Science , vol.296 , pp. 1703
- Urizar, N.L.¹ Liverman, A.B.² Dodds, D.N.T.³ Silva, F.V.⁴ Ordentlich, P.⁵ Yan, Y.⁶ Gonzalez, F.J.⁷ Heyman, R.A.⁸ Mangelsdorf, D.J.⁹ Moore, D.D.¹⁰

26
- 0037199946
- J. Yu, J.-L. Lo, L. Huang, A. Zhao, E. Metzger, A. Adams, P.T. Meinke, S.D. Wright, and J. Cui J. Biol. Chem. 277 2002 31441
- (2002) J. Biol. Chem. , vol.277 , pp. 31441
- Yu, J.¹ Lo, J.-L.² Huang, L.³ Zhao, A.⁴ Metzger, E.⁵ Adams, A.⁶ Meinke, P.T.⁷ Wright, S.D.⁸ Cui, J.⁹

27
- 33748302808
- S.-J. Nam, H. Ko, M. Shin, J. Ham, J. Chin, Y. Kim, H. Kim, K. Shin, H. Choi, and H. Kang Bioorg. Med. Chem. Lett. 16 2006 5398
- (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 5398
- Nam, S.-J.¹ Ko, H.² Shin, M.³ Ham, J.⁴ Chin, J.⁵ Kim, Y.⁶ Kim, H.⁷ Shin, K.⁸ Choi, H.⁹ Kang, H.¹⁰

28
- 34548142208
- B.A. Carter, O.A. Taylor, D.R. Prendergast, T.L. Zimmerman, F.R. Von, D.D. Moore, and S.J. Karpen Pediatr. Res. 62 2007 301
- (2007) Pediatr. Res. , vol.62 , pp. 301
- Carter, B.A.¹ Taylor, O.A.² Prendergast, D.R.³ Zimmerman, T.L.⁴ Von, F.R.⁵ Moore, D.D.⁶ Karpen, S.J.⁷

29
- 79951546028
- H. Choi, H. Hwang, J. Chin, E. Kim, J. Lee, S.-J. Nam, B.C. Lee, B.J. Rho, and H. Kang J. Nat. Prod. 74 2011 90
- (2011) J. Nat. Prod. , vol.74 , pp. 90
- Choi, H.¹ Hwang, H.² Chin, J.³ Kim, E.⁴ Lee, J.⁵ Nam, S.-J.⁶ Lee, B.C.⁷ Rho, B.J.⁸ Kang, H.⁹

30
- 84858342203
- M.Y. Putra, G. Bavestrello, C. Cerrano, B. Renga, C. D'Amore, S. Fiorucci, E. Fattorusso, and O. Taglialatela-Scafati Steroids 77 2012 433
- (2012) Steroids , vol.77 , pp. 433
- Putra, M.Y.¹ Bavestrello, G.² Cerrano, C.³ Renga, B.⁴ D'Amore, C.⁵ Fiorucci, S.⁶ Fattorusso, E.⁷ Taglialatela-Scafati, O.⁸

31
- 79952274483
- V. Sepe, G. Bifulco, B. Renga, C. D'Amore, S. Fiorucci, and A. Zampella J. Med. Chem. 54 2011 1314
- (2011) J. Med. Chem. , vol.54 , pp. 1314
- Sepe, V.¹ Bifulco, G.² Renga, B.³ D'Amore, C.⁴ Fiorucci, S.⁵ Zampella, A.⁶

32
- 84879060437
- F.S. Di Leva, C. Festa, C. D'Amore, S. De Marino, B. Renga, M.V. D'Auria, E. Novellino, V. Limongelli, A. Zampella, and S. Fiorucci J. Med. Chem. 56 2013 4701
- (2013) J. Med. Chem. , vol.56 , pp. 4701
- Di Leva, F.S.¹ Festa, C.² D'Amore, C.³ De Marino, S.⁴ Renga, B.⁵ D'Auria, M.V.⁶ Novellino, E.⁷ Limongelli, V.⁸ Zampella, A.⁹ Fiorucci, S.¹⁰

33
- 84884991556
- X. Xu, Y. Lu, L. Chen, J. Chen, X. Luo, and X. Shen Steroids 78 2013 813
- (2013) Steroids , vol.78 , pp. 813
- Xu, X.¹ Lu, Y.² Chen, L.³ Chen, J.⁴ Luo, X.⁵ Shen, X.⁶

34
- 33847780436
- M. Kainuma, M. Makishima, Y. Hashimoto, and H. Miyachi Bioorg. Med. Chem. 15 2007 2587
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 2587
- Kainuma, M.¹ Makishima, M.² Hashimoto, Y.³ Miyachi, H.⁴

35
- 0026611395
- D.K. Herron, T. Goodson, N.G. Bollinger, D. Swanson-Bean, I.G. Wright, G.S. Staten, A.R. Thompson, L.L. Froelich, and W.T. Jackson J. Med. Chem. 35 1992 1818
- (1992) J. Med. Chem. , vol.35 , pp. 1818
- Herron, D.K.¹ Goodson, T.² Bollinger, N.G.³ Swanson-Bean, D.⁴ Wright, I.G.⁵ Staten, G.S.⁶ Thompson, A.R.⁷ Froelich, L.L.⁸ Jackson, W.T.⁹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.