Molecular imaging of pulmonary nodules

American Journal of Roentgenology

Volumn 202, Issue 3, 2014, Pages

  Maffione, Anna Margherita ^a   Grassetto, Gaia ^a   Rampin, Lucia ^a   Chondrogiannis, Sotirios ^a   Marzola, Maria Cristina ^a   Ambrosini, Valentina ^b   Rubello, Domenico ^a  

^a SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

18F dihydroxyphenylalanine; 18F fluorodeoxythymidine; 18F methionine; 68Ga DOTA peptides; FDG; Lung nodule molecular imaging; PET CT

Indexed keywords

3' FLUOROTHYMIDINE F 18; 6 FLUORODOPA F 18; FLUORODEOXYGLUCOSE F 18; METHIONINE C 11; PASIREOTIDE TETRAXETAN GALLIUM GA 68; RADIOPHARMACEUTICAL AGENT; TETRAXETAN GA 68; UNCLASSIFIED DRUG;

BRAIN METASTASIS; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DRUG UPTAKE; FALSE POSITIVE RESULT; HISTOPLASMOSIS; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE RECONSTRUCTION; LUNG ABSCESS; LUNG ADENOCARCINOMA; LUNG LESION; LUNG NODULE; LUNG SARCOIDOSIS; LUNG TUBERCULOSIS; MOLECULAR IMAGING; NEUROENDOCRINE TUMOR; PNEUMONIA; PREDICTIVE VALUE; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; WEGENER GRANULOMATOSIS;

CHILD; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR IMAGING; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SOLITARY PULMONARY NODULE;

EID: 84896728327     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.13.11733     Document Type: Review

References (52)

1. Taylor RR, Rivkin LN, Salyer JM. The solitary pulmonary nodule: a review of 236 consecutive cases, 1944 to 1956. Ann Surg 1958; 147:197-202
2. Ost D, Fein AM, Feinsilver SH. Clinical practice: the solitary pulmonary nodule. N Engl J Med 2003; 348:2535-2542 (Pubitemid 36712195)
3. Swensen SJ, Jett JR, Hartman TE, et al. CT screening for lung cancer: five-year prospective experience. Radiology 2005; 235:259-265 (Pubitemid 40432263)
4. Gupta NC, Frank AR, Dewan NA, et al. Solitary pulmonary nodules: detection of malignancy with PET with 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology 1992; 184:441-444
5. Zasadny KR, Wahl RL. Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose: variations with body weight and a method for correction. Radiology 1993; 189:847-850 (Pubitemid 23354506)
6. Patz EF Jr, Lowe VJ, Hoffman JM, et al. Focal pulmonary abnormalities: evaluation with F-18 fluorodeoxyglucose PET scanning. Radiology 1993; 188:487-490 (Pubitemid 23216276)
7. Townsend DW. Combined PET/CT: the historical perspective. Semin Ultrasound CT MR 2008; 29:232-235
8. Jaroff L. Time Magazine's medical invention of the year 2000. Time Magazine, December 4, 2000
9. Wagner HN Jr. Fused image tomography: where do we go from here? J Nucl Med 1999; 40:30N-33N (Pubitemid 29471144)
10. Kinahan PE, Townsend DW, Beyer T, et al. Attenuation correction for a combined 3D PET/CT scanner. Med Phys 1998; 25:2046-2053
11. Ost DE, Gould MK. Decision making in patients with pulmonary nodules. Am J Respir Crit Care Med 2012; 185:363-372
12. Gupta NC, Maloof J, Gunel E. Probability of malignancy in solitary pulmonary nodules using fluorine-18-FDG and PET. J Nucl Med 1996; 37:943-948 (Pubitemid 126447126)
13. Bury T, Dowlati A, Paulus P, et al. Evaluation of the solitary pulmonary nodule by positron emission tomography imaging. Eur Respir J 1996; 9:410-414 (Pubitemid 26117781)
14. Christensen JA, Nathan MA, Mullan BP, Hartman TE, Swensen SJ, Lowe VJ. Characterization of the solitary pulmonary nodule: 18F-FDG PET versus nodule-enhancement CT. AJR 2006; 187:1361-1367 (Pubitemid 44630846)
15. Gould MK, Maclean CC, Kuschner WG. Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions: a meta-analysis. JAMA 2001; 285:914-924 (Pubitemid 32171553)
16. Fletcher JW, Kymes SM, Gould M, et al.; Cooperative Studies Group. A comparison of the diagnostic accuracy of 18F-FDG PET and CT in the characterization of solitary pulmonary nodules. J Nucl Med 2008; 49:179-185 (Pubitemid 351225654)
17. Fletcher JW, Lowe VJ. Is PET ready for prime time? J Nucl Med 1996; 37:948-949
18. Tsushima Y, Tateishi U, Uno H, et al. Diagnostic performance of PET/CT in differentiation of malignant and benign non-solid solitary pulmonary nodules. Ann Nucl Med 2008; 22:571-577
19. Kim SK, Allen-Auerbach M, Goldin J, et al. Accuracy of PET/CT in characterization of solitary pulmonary lesions. J Nucl Med 2007; 48:214-220 (Pubitemid 47555346)
20. Divisi D, Di Tommaso S, Di Leonardo G, Brianzoni E, De Vico A, Crisci R. 18-Fluorine fluorodeoxyglucose positron emission tomography with computerized tomography versus computerized tomography alone for the management of solitary lung nodules with diameters inferior to 1.5 cm. Thorac Cardiovasc Surg 2010; 58:422-426
21. Tsushima Y, Aoki J, Endo K. Whether and under what conditions FDG-PET might be cost-effective in evaluating solitary pulmonary nodules depicted on lung cancer screening in Japan (in Japanese). Nihon Igaku Hoshasen Gakkai Zasshi 2003; 63:390-398
22. Schrevens L, Lorent N, Dooms C, Vansteenkiste J. The role of PET scan in diagnosis, staging, and management of non-small cell lung cancer. Oncologist 2004; 9:633-643 (Pubitemid 39546404)
23. 18F] fluoro-2-deoxyglucose positron emission tomography in preoperative management of solid-type small-sized lung cancer. Ann Nucl Med 2013; 27:515-522
24. Lee HY, Lee KS. Ground-glass opacity nodules: histopathology, imaging evaluation, and clinical implications. J Thorac Imaging 2011; 26:106-118
25. Minamimoto R, Senda M, Jinnouchi S, et al. The current status of an FDG-PET cancer screening program in Japan, based on a 4-year (2006-2009) nationwide survey. Ann Nucl Med 2013; 27:46-57
26. Patel VK, Naik SK, Naidich DP, et al. A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules. Part 2. Pretest probability and algorithm. Chest 2013; 143:840-846
27. Sebro R, Aparici CM, Hernandez-Pampaloni M. FDG PET/CT evaluation of pathologically proven pulmonary lesions in an area of high endemic granulomatous disease. Ann Nucl Med 2013; 27:400-405
28. 18F-FDG PET imaging for differentiating malignant from inflammatory processes. J Nucl Med 2001; 42:1412-1417
29. Macdonald K, Searle J, Lyburn I. The role of dual time point FDG PET imaging in the evaluation of solitary pulmonary nodules with an initial standard uptake value less than 2.5. Clin Radiol 2011; 66:244-250
30. 18FDG-PET/CT for the differential diagnosis of pulmonary nodules: a meta-analysis. Acta Radiol 2013; 54:770-777
31. Werner MK, Parker JA, Kolodny GM, English JR, Palmer MR. Respiratory gating enhances imaging of pulmonary nodules and measurement of tracer uptake in FDG PET/CT. AJR 2009; 193:1640-1645
32. MacMahon H, Austin JH, Gamsu G, et al. Fleischner Society Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology 2005; 237:395-400 (Pubitemid 41507873)
33. Khan AN, Al-Jahdali HH, Irion KL, Arabi M, Koteyar SS. Solitary pulmonary nodule: a diagnostic algorithm in the light of current imaging technique. Avicenna J Med 2011; 1:39-51
34. National Comprehensive Cancer Network (NCCN). NCCN clinical practice guidelines in oncology: lung cancer screening - version 1.2014. NCCN website. www.nccn.org/patients/guidelines/lung-screening/files/assets/basic-html/page1. html. Accessed July 29, 2013
35. 18F- fluorodeoxyglucose and SUV quantification. Eur J Nucl Med Mol Imaging 2010; 37:1087-1094
36. Dewan NA, Gupta NC, Redepenning LS, Phalen JJ, Frick MP. Diagnostic efficacy of PET-FDG imaging in solitary pulmonary nodules: potential role in evaluation and management. Chest 1993; 104:997-1002 (Pubitemid 23306039)
37. Keith CJ, Miles KA, Griffiths MR, Wong D, Pitman AG, Hicks RJ. Solitary pulmonary nodules: accuracy and cost-effectiveness of sodium iodide FDG-PET using Australian data. Eur J Nucl Med Mol Imaging 2002; 29:1016-1023
38. Kitajima K, Suzuki K, Nakamoto Y, et al. Low-dose non-enhanced CT versus full-dose contrast-enhanced CT in integrated PET/CT studies for the diagnosis of uterine cancer recurrence. Eur J Nucl Med Mol Imaging 2010; 37:1490-1498
39. Pfluger T, Melzer HI, Schneider V, et al. PET/CT in malignant melanoma: contrast-enhanced CT versus plain low-dose CT. Eur J Nucl Med Mol Imaging 2011; 38:822-831
40. Kitajima K, Suzuki K, Senda M, et al. Preoperative nodal staging of uterine cancer: is contrast-enhanced PET/CT more accurate than non-enhanced PET/CT or enhanced CT alone? Ann Nucl Med 2011; 25:511-519
41. Nanni C, Zompatori M, Ambrosini V, et al. The additional diagnostic value of contemporary evaluation of FDG PET/CT scan and contrast enhanced CT imaging both acquired by a last generation PET/CT system in oncologic patients. Biomed Pharmacother 2013; 67:172-178
42. Travaini L, Trifiró G, Vigna P, Veronesi G, De Pas T, Spaggiari L, Paganelli G, Bellomi M. Roles of computer tomography and [(18)F] fluorodeoxyglucose-positron emission tomography/computed tomography in the characterization of multiple solitary solid lung nodules. Ecancermedicalscience 2012; 6:266
43. Shields AF, Grierson JR, Kozawa SM, Zheng M. Development of labeled thymidine analogs for imaging tumor proliferation. Nucl Med Biol 1996; 23:17-22 (Pubitemid 26050366)
44. Buck AK, Hetzel M, Schirrmeister H, et al. Clinical relevance of imaging proliferative activity in lung nodules. Eur J Nucl Med Mol Imaging 2005; 32:525-533 (Pubitemid 41214194)
45. Evangelista L, Panunzio A, Cervino AR, Vinante L, Al-Nahhas A, Rubello D, Muzzio PC, Polversoi R. Indeterminate pulmonary nodules on CT images in breast cancer patient: the additional value of 18F-FDG PET/CT. J Med Imaging Radiat Oncol 2012; 56:417-424
46. 18F] FLT PET for diagnosis and staging of thoracic tumours. Eur J Nucl Med Mol Imaging 2003; 30:1407-1412
47. Kubota K, Yamada K, Fukuda H, et al. Tumor detection with carbon-11-labelled amino acids. Eur J Nucl Med 1984; 9:136-140 (Pubitemid 14173032)
48. 18F-FDG-PET. Ann Nucl Med 2008; 22:533-538
49. 11C-methionine PET in imaging brain tumours and metastases. Eur J Nucl Med Mol Imaging 2013; 40:615-635
50. Ambrosini V, Nicolini S, Caroli P, et al. PET/CT imaging in different types of lung cancer: an overview. Eur J Radiol 2012; 81:988-1001
51. 18F-DOPA PET for the detection of gastro-enteropancreatic and lung neuro-endocrine tumours. Eur J Nucl Med Mol Imaging 2008; 35:1431-1438
52. Caroli P, Nanni C, Rubello D, Alavi A, Fanti S. Non-FDG PET in the practice of oncology. Indian J Cancer 2010; 47:120-125