Should we treat asymptomatic bacteriuria after renal transplantation?

Nephrology Dialysis Transplantation

Volumn 29, Issue 2, 2014, Pages 260-262

  Coussement, Julien ^a   Abramowicz, Daniel ^b  

^a ERASME HOSPITAL   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC RESISTANCE; ASYMPTOMATIC BACTERIURIA; BACTERIAL COUNT; BACTERIAL VIRULENCE; CLINICAL PRACTICE; COST OF ILLNESS; CYSTITIS; DRUG COST; DRUG MISUSE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; HUMAN; INFECTION RISK; KIDNEY TRANSPLANTATION; NONHUMAN; PREMENOPAUSE; PRIORITY JOURNAL; PYELONEPHRITIS; RECURRENT INFECTION; REVIEW; TREATMENT PLANNING; URINE CULTURE;

ANTI-BACTERIAL AGENTS; BACTERIURIA; DECISION MAKING; HUMANS; INCIDENCE; KIDNEY TRANSPLANTATION; PROGNOSIS; SURGICAL WOUND INFECTION; SURVIVAL RATE; WORLD HEALTH;

EID: 84896727519     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gft432     Document Type: Review

References (30)

1. Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007; 357: 2601-2614
2. Alangaden GJ, Thyagarajan R, Gruber SA et al. Infectious complications after kidney transplantation: Current epidemiology and associated risk factors. Clin Transplant 2006; 20: 401-409
3. Maraha B, Bonten H, Van Hooff H et al. Infectious complications and antibiotic use in renal transplant recipients during a 1-year follow-up. Clin Microbiol Infect 2001; 7: 619-625
4. Vidal E, Torre-Cisneros J, Blanes M et al. Bacterial urinary tract infection after solid organ transplantation in the RESITRA cohort. Transpl Infect Dis 2012; 14: 595-603
5. Veroux M, Giuffrida G, Corona D et al. Infective complications in renal allograft recipients: Epidemiology and outcome. Transplant Proc 2008; 40: 1873-1876
6. Giral M, Pascuariello G, Karam G et al. Acute graft pyelonephritis and long-Term kidney allograft outcome. Kidney Int 2002; 61: 1880-1886
7. Pelle G, Vimont S, Levy PP et al. Acute pyelonephritis represents a risk factor impairing long-Term kidney graft function. Am J Transplant 2007; 7: 899-907
8. Abbott KC, Swanson SJ, Richter ER et al. Late urinary tract infection after renal transplantation in the United States. Am J Kidney Dis 2004; 44: 353-362
9. Kamath NS, John GT, Neelakantan N et al. Acute graft pyelonephritis following renal transplantation. Transpl Infect Dis 2006; 8: 140-147
10. Fiorante S, Fernandez-Ruiz M, Lopez-Medrano F et al. Acute graft pyelonephritis in renal transplant recipients: Incidence, risk factors and longterm outcome. Nephrol Dial Transplant 2011; 26: 1065-1073
11. Parasuraman R, Julian K. Urinary tract infections in solid organ transplantation. Am J Transplant 2013; 13: 327-336
12. Nicolle LE, Bradley S, Colgan R et al. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005; 40: 643-654
13. Kunin CM. Asymptomatic bacteriuria. Annu Rev Med 1966; 17: 383-406
14. Hooton TM, Scholes D, Stapleton AE et al. A prospective study of asymptomatic bacteriuria in sexually active young women. N Engl J Med 2000; 343: 992-997
15. Fiorante S, Lopez-Medrano F, Lizasoain M et al. Systematic screening and treatment of asymptomatic bacteriuria in renal transplant recipients. Kidney Int 2010; 78: 774-781
16. El Amari EB, Hadaya K, Buhler L et al. Outcome of treated and untreated asymptomatic bacteriuria in renal transplant recipients. Nephrol Dial Transplant 2011; 26: 4109-4114
17. Moradi M, Abbasi M, Moradi A et al. Effect of antibiotic therapy on asymptomatic bacteriuria in kidney transplant recipients. Urol J 2005; 2: 32-35
18. Green H, Rahamimov R, Goldberg E et al. Consequences of treated versus untreated asymptomatic bacteriuria in the first year following kidney transplantation: Retrospective observational study. Eur J Clin Microbiol Infect Dis 2012; 32: 127-131
19. Harding GK, Zhanel GG, Nicolle LE et al. Antimicrobial treatment in diabetic women with asymptomatic bacteriuria. N Engl J Med 2002; 347: 1576-1583
20. Boscia JA, Kobasa WD, Knight RA et al. Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. JAMA 1987; 257: 1067-1071
21. Nicolle LE, Bjornson J, Harding GK et al. Bacteriuria in elderly institutionalized men. N Engl J Med 1983; 309: 1420-1425
22. Mohler JL, Cowen DL, Flanigan RC. Suppression and treatment of urinary tract infection in patients with an intermittently catheterized neurogenic bladder. J Urol 1987; 138: 336-340
23. Cai T, Mazzoli S, Mondaini N et al. The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: To treat or not to treat?. Clin Infect Dis 2012; 55: 771-777
24. Nielubowicz GR, Mobley HL. Host-pathogen interactions in urinary tract infection. Nat Rev Urol 2010; 7: 430-441
25. Rice JC, Peng T, Kuo YF et al. Renal allograft injury is associated with urinary tract infection caused by escherichia coli bearing adherence factors. Am J Transplant 2006; 6: 2375-2383
26. Wagenlehner FM, Naber KG. Asymptomatic bacteriuria-shift of paradigm. Clin Infect Dis 2012; 55: 778-780
27. Kasiske BL, Zeier MG, Chapman JR et al. KDIGO Clinical practice guideline for the care of kidney transplant recipients: A summary. Kidney Int 2010; 77: 299-311
28. Fernández NS. Antibiotic treatment versus no therapy in kidney transplant recipients with asymptomatic bacteriuria. Clinicaltrials.gov. http ://clinicaltrials.gov/ct2/show/study/NCT01771432
29. Coussement J, Abramowicz D,Wissing KM et al. The Bacteriuria in Renal Transplantation (BiRT) study: A prospective, randomized, parallel-group, multicenter, open-label, superiority trial comparing antibiotics versus no treatment in the prevention of symptomatic urinary tract infection in kidney transplant recipients with asymptomatic bacteriuria. Clinicaltrials. gov. http://clinicaltrials.gov/ct2/show/NCT01871753
30. Origüen J, López-Medrano F, Pérez-Jacoiste M et al. Prospective Comparative Study of a Strategy of Systematic Search and Treatment Versus No Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients: Preliminary Results. Abstract number: B1045. Seattle: American Transplant Congress, 2013