Risk of scar in the comparison of Age-related Macular Degeneration Treatments Trials

Ophthalmology

Volumn 121, Issue 3, 2014, Pages 656-666

  Daniel, Ebenezer ^a   Toth, Cynthia A ^b   Grunwald, Juan E ^a   Jaffe, Glenn J ^b   Martin, Daniel F ^c   Fine, Stuart L ^d   Huang, Jiayan ^a   Ying, Gui Shuang ^a   Hagstrom, Stephanie A ^c   Winter, Katrina ^b   Maguire, Maureen G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DUKE UNIVERSITY   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; RANIBIZUMAB;

ADULT; ARTICLE; DEMOGRAPHY; EYE PHOTOGRAPHY; FLUORESCENCE ANGIOGRAPHY; GENOTYPE; HUMAN; HYPERPIGMENTATION; INCIDENCE; MAJOR CLINICAL STUDY; OPTICAL COHERENCE TOMOGRAPHY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RETINA MACULA AGE RELATED DEGENERATION; RETINAL THICKNESS; RISK FACTOR; SCAR; SCAR FORMATION; SUBRETINAL NEOVASCULARIZATION; VISUAL ACUITY;

ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; CICATRIX; COHORT STUDIES; FEMALE; FIBROSIS; FLUORESCEIN ANGIOGRAPHY; GENOTYPE; HUMANS; INCIDENCE; INTRAVITREAL INJECTIONS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; RETINA; RISK FACTORS; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY; WET MACULAR DEGENERATION;

EID: 84896720094     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2013.10.019     Document Type: Article

References (40)

1. G.J. Jaffe, D.F. Martin, C.A. Toth Comparison of Age-related Macular Degeneration Treatments Trials Research Group Macular morphology and visual acuity in the Comparison of Age-related Macular Degeneration Treatments Trials Ophthalmology 120 2013 1860 1870
2. N.M. Bressler, L.A. Frost, and S.B. Bressler et al. Natural course of poorly defined choroidal neovascularization associated with macular degeneration Arch Ophthalmol 106 1988 1537 1542
3. T.Y. Wong, U. Chakravarthy, and R. Klein et al. The natural history and prognosis of neovascular age-related macular degeneration: a systematic review of the literature and meta-analysis Ophthalmology 115 2008 116 126
4. D. Pauleikhoff Neovascular age-related macular degeneration: natural history and treatment outcomes Retina 25 2005 1065 1084
5. S. Sivaprasad, G.M. Saleh, and H. Jackson Does lesion size determine the success rate of photodynamic therapy for age-related macular degeneration? Eye (Lond) 20 2006 43 45
6. AMDRT Research Group The Age-Related Macular Degeneration Radiotherapy Trial (AMDRT): one year results from a pilot study Am J Ophthalmol 138 2004 818 828
7. R. Trikha, L.S. Morse, and R.J. Zawadzki et al. Ten-year follow-up of eyes treated with stereotactic fractionated external beam radiation for neovascular age-related macular degeneration Retina 31 2011 1303 1315
8. L.H. Curtis, B.G. Hammill, and L.G. Qualls et al. Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 Medicare beneficiaries Am J Ophthalmol 153 2012 1116 1124
9. S.Y. Cohen, H. Oubraham, and J. Uzzan et al. Causes of unsuccessful ranibizumab treatment in exudative age-related macular degeneration in clinical settings Retina 32 2012 1480 1485
10. CATT Research Group Ranibizumab and bevacizumab for neovascular age-related macular degeneration N Engl J Med 364 2011 1897 1908
11. J.E. Grunwald, E. Daniel, G.S. Ying CATT Research Group Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments Trials Ophthalmology 119 2012 1634 1641
12. F.C. DeCroos, C.A. Toth, S.S. Stinnett CATT Research Group Optical coherence tomography grading reproducibility during the Comparison of Age-related Macular Degeneration Treatments Trials Ophthalmology 119 2012 2549 2557
13. P.K. Kaiser, B.A. Blodi, H. Shapiro, N.R. Acharya MARINA Study Group Angiographic and optical coherence tomographic results of the MARINA study of ranibizumab in neovascular age-related macular degeneration Ophthalmology 114 2007 1868 1875
14. Y. Benjamini, and Y. Hochberg Controlling the false discovery rate: a practical and powerful approach to multiple testing J R Stat Soc Series B (Methodol) 57 1995 289 300
15. P.E. Beaumont, and H.K. Kang Lesion morphology in age-related macular degeneration and its therapeutic significance Arch Ophthalmol 124 2006 807 812
16. P.J. Rosenfeld, H. Shapiro, L. Tuomi MARINA and ANCHOR Study Groups Characteristics of patients losing vision after 2 years of monthly dosing in the phase III ranibizumab clinical trials Ophthalmology 118 2011 523 530
17. N.M. Bressler, S.B. Bressler, and S.L. Fine Age-related macular degeneration Surv Ophthalmol 32 1988 375 413
18. H. Zauberman, M. Ivry, and U. Sachs The macular vessels in predisciform and disciform senile macular degeneration Am J Ophthalmol 70 1970 498 504
19. Z. Gregor, A.C. Bird, and I.H. Chisholm Senile disciform macular degeneration in the second eye Br J Ophthalmol 61 1977 141 147
20. W.R. Green, and C. Enger Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture Ophthalmology 100 1993 1519 1535
21. S.Y. Kim, S. Sadda, and J. Pearlman et al. Morphometric analysis of the macula in eyes with disciform age-related macular degeneration Retina 22 2002 471 477
22. R. Hogg, E. Curry, and A. Muldrew et al. Identification of lesion components that influence visual function in age related macular degeneration Br J Ophthalmol 87 2003 609 614
23. D.M. Brown, P.K. Kaiser, M. Michels ANCHOR Study Group Ranibizumab versus verteporfin for neovascular age-related macular degeneration N Engl J Med 355 2006 1432 1444
24. P.J. Rosenfeld, D.M. Brown, J.S. Heier MARINA Study Group Ranibizumab for neovascular age-related macular degeneration N Engl J Med 355 2006 1419 1431
25. J.S. Heier, D. Boyer, Q.D. Nguyen CLEAR-IT 2 Investigators The 1-year results of CLEAR-IT 2, a phase 2 study of vascular endothelial growth factor Trap-Eye dosed as-needed after 12-week fixed dosing Ophthalmology 118 2011 1098 1106
26. P.K. Kaiser, D.M. Brown, and K. Zhang et al. Ranibizumab for predominantly classic neovascular age-related macular degeneration: subgroup analysis of first-year ANCHOR results Am J Ophthalmol 144 2007 850 857
27. Y.B. Unver, G.A. Yavuz, and N. Bekiroǧlu et al. Relationships between clinical measures of visual function and anatomic changes associated with bevacizumab treatment for choroidal neovascularization in age-related macular degeneration Eye (Lond) 23 2009 453 460
28. T.A. Wilgus, A.M. Ferreira, and T.M. Oberyszyn et al. Regulation of scar formation by vascular endothelial growth factor Lab Invest 8 2000 579 590
29. E.C. O'Neill, Q. Qin, and N.J. Van Bergen et al. Antifibrotic activity of bevacizumab on human Tenon's fibroblasts in vitro Invest Ophthalmol Vis Sci 51 2010 6524 6532
30. Z. Li, T. Van Bergen, and S. Van de Veire et al. Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery Invest Ophthalmol Vis Sci 50 2009 5217 5225
31. F. Memarzadeh, R. Varma, and L.T. Lin et al. Postoperative use of bevacizumab as an antifibrotic agent in glaucoma filtration surgery in the rabbit Invest Ophthalmol Vis Sci 50 2009 3233 3237
32. R.J. Van Geest, S.Y. Lesnik-Oberstein, and H.S. Tan et al. A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy Br J Ophthalmol 96 2012 587 590
33. E.J. Kuiper, M.D. de Smet, and J.C. van Meurs et al. Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye Arch Ophthalmol 124 2006 1457 1462
34. T.S. Stevens, N.M. Bressler, and M.G. Maguire et al. Occult choroidal neovascularization in age-related macular degeneration. A natural history study Arch Ophthalmol 115 1997 345 350
35. A. Scupola, G. Coscas, G. Soubrane, and E. Balestrazzi Natural history of macular subretinal hemorrhage in age-related macular degeneration Ophthalmologica 213 1999 97 102
36. R.L. Avery, S. Fekrat, B.S. Hawkins, and N.M. Bressler Natural history of subfoveal subretinal hemorrhage in age-related macular degeneration Retina 16 1996 183 189
37. J.C. Hwang, L.V. Del Priore, and K.B. Freund et al. Development of subretinal fibrosis after anti-VEGF treatment in neovascular age-related macular degeneration Ophthalmic Surg Lasers Imaging 42 2011 6 11
38. F. Viola, A. Massacesi, and N. Orzalesi et al. Retinal angiomatous proliferation: natural history and progression of visual loss Retina 29 2009 732 739
39. A.A. Rouvas, I.P. Chatziralli, and P.G. Theodossiadis et al. Long-term results of intravitreal ranibizumab, intravitreal ranibizumab with photodynamic therapy, and intravitreal triamcinolone with photodynamic therapy for the treatment of retinal angiomatous proliferation Retina 32 2012 1181 1189
40. M. Nakashima, S. Chung, and A. Takahashi et al. A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population Nat Genet 42 2010 768 771