Automated Discovery of Tissue-Targeting Enhancers and Transcription Factors from Binding Motif and Gene Function Data

PLoS Computational Biology

Volumn 10, Issue 1, 2014, Pages

  Tuteja, Geetu ^a   Moreira, Karen Betancourt ^a   Chung, Tisha ^a   Chen, Jenny ^a   Wenger, Aaron M ^b   Bejerano, Gill ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BLOOD VESSELS; DIGITAL STORAGE; GENE EXPRESSION REGULATION; TISSUE; TRANSCRIPTION;

AUTOMATED DISCOVERY; BINDING MOTIF; BINDING SITE PREDICTIONS; COMPUTATIONAL FRAMEWORK; EPIGENOMICS; GENE FUNCTION; GENES EXPRESSION; HIGH CONFIDENCE; TISSUE SPECIFICS; TISSUE TARGETING;

TRANSCRIPTION FACTORS;

LUCIFERASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BLOOD VESSEL; BONE MARROW; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; EPIGENETICS; FEMALE; GENE CLUSTER; GENE FUNCTION; GENE LIBRARY; GENE LOCUS; GENE TARGETING; GENETIC DATABASE; HEART MUSCLE; HUMAN; LIVER PARENCHYMA; MOUSE; NONHUMAN; PANCREAS; PHENOTYPE; PLACENTA DEVELOPMENT; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; TROPHOBLAST;

ALGORITHMS; AMINO ACID MOTIFS; ANIMALS; AUTOMATION; BINDING SITES; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; ENHANCER ELEMENTS, GENETIC; EPIGENOMICS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICE; PLACENTA; PREGNANCY; TRANSCRIPTION FACTORS; TROPHOBLASTS;

EID: 84896719342     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003449     Document Type: Article

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