Prevention of etomidate-induced myoclonus: Which is superior: Fentanyl, midazolam, or a combination? A Retrospective comparative study

Medical Science Monitor

Volumn 20, Issue , 2014, Pages 262-267

  Isitemiz, Ilke ^a   Uzman, Sinan ^a   Toptaş, Mehmet ^a   Vahapoglu, Ayşe ^a   Gül, Yaşar Gökhan ^b   Inal, Ferda Yilmaz ^a   Akkoc, Ibrahim ^a  

^a HASEKI EDUCATION AND RESEARCH HOSPITAL   (Turkey)

^b Kartal Kosuyolu High Speciality Training and Research Hospital   (Turkey)

Author keywords

Etomidate; Fentanyl; Midazolam; Myoclonus chemically induced

Indexed keywords

ETOMIDATE; FENTANYL; MIDAZOLAM; SEVOFLURANE; VECURONIUM; INTRAVENOUS ANESTHETIC AGENT;

ADULT; ANESTHESIA INDUCTION; ARTICLE; COMPARATIVE STUDY; ENDOTRACHEAL INTUBATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MYOCLONUS; RETROSPECTIVE STUDY; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG COMBINATION; DRUG EFFECTS; HEART RATE; NONPARAMETRIC TEST; PROCEDURES;

ANESTHETICS, INTRAVENOUS; BLOOD PRESSURE; DRUG THERAPY, COMBINATION; ETOMIDATE; FENTANYL; HEART RATE; HUMANS; MIDAZOLAM; MYOCLONUS; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 84896718644     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.889833     Document Type: Article

References (25)

1. Ouedraogo N, Roux E, Forestier F et al: Effects of intravenous anesthetics on normal and passively sensitized human isolated airway smooth muscle. Anesthesiology, 1998; 88(2): 317-26
2. Yeung JK, Zed PJ: A review of etomidate for rapid sequence intubation in the emergency department. CJEM, 2002; 4(3): 194-98
3. Baird CR, Hay AW, McKeown DW, Ray DC: Rapid sequence induction in the emergency department: induction drug and outcome of patients admitted to the intensive care unit. Emerg Med J, 2009; 26(8): 576-79
4. Reich DL, Hossain S, Krol M et al: Predictors of hypotension after induction of general anesthesia. Anesth Analg, 2005; 101(3): 622-28
5. Malinowska-Zaprzałka M, Wojewódzka M, Dryl D et al: Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Pharmacol Rep, 2005; 57(5): 675-78
6. Bergen JM, Smith DC: A review of etomidate for rapid sequence intubation in the emergency department. J Emerg Med, 1997; 15(2): 221-30
7. Dhawan N, Chauhan S, Kothari SS et al: Hemodynamic Responses to Etomidate in Pediatric Patients with Congenital Cardiac Shunt Lesions. J Cardiothorac Vasc Anesth, 2010; 24(5): 802-7
8. Doenicke AW, Roizen MF, Kugler J et al: Reducing myoclonus after etomidate. Anesthesiology, 1999; 90(1): 113-19
9. Berry JM, Merin RG: Etomidate myoclonus and the open globe. Anesth Analg, 1989; 69: 256-59
10. Stockham RJ, Stanley TH, Pace NL et al: Fentanyl pretreatment modifies anaesthetic induction with etomidate. Anaesth Intensive Care, 1988; 16: 171-76
11. Schwarzkopf KR, Hueter L, Simon M, Fritz HG: Midazolam pretreatment reduces etomidate-induced myoclonic movements. Anaesth Intensive Care, 2003; 31(1): 18-20
12. Hwang JY, Kim JH, Oh AY et al: A comparison of midazolam with remifentanil for the prevention of myoclonic movements following etomidate injection. J Int Med Res, 2008; 36(1): 17-22
13. Nyman Y, Von Hofsten K, Palm C et al: Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine. Br J Anaesth, 2006; 97(4): 536-39
14. Hüter L, Schreiber T, Gugel M, Schwarzkopf K: Low-dose intravenous midazolam reduces etomidate-induced myoclonus: a prospective, randomized study in patients undergoing elective cardioversion. Anesth Analg, 2007; 105(5): 1298-302
15. Hueter L, Schwarzkopf K, Simon M et al: Pretreatment with sufentanil reduces myoclonus after etomidate. Acta Anaesthesiol Scand, 2003; 47(4): 482-84
16. Guler A, Satilmis T, Akinci SB et al: Magnesium sulfate pretreatment reduces myoclonus after etomidate. Anesth Analg, 2005; 101(3): 705-9
17. Mizrak A, Koruk S, Bilgi M et al: Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate: a randomized, doubleblind controlled trial. J Surg Res, 2010; 159(1): e11-16
18. Gultop F, Akkaya T, Bedirli N, Gumus H: Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate. J Anesth, 2010; 24(2): 300-2
19. Do SH, Han SH, Park SH et al: The effect of injection rate on etomidate-induced myoclonus. Korean J Anesthesiol, 2008; 55(3): 305-7
20. Sati{dotless}lmi{dotless}s T Guler A, Pamuk AG et al: The comparison of different doses of magnesium sulfate to prevent myclonus after etomidate induction. J Turk Anaesth Int Care, 2010; 38(3): 184-89
21. Pasternak GW: Preclinical pharmacology and opioid combinations. Pain Med, 2012; 13(s1): S4-S11
22. White PF, Eng MR: Intravenous anesthetics. In: Barash PG, Cullen BF, Stoelting RK et al. (eds.), Clinical anesthesia. 6th ed. Philadelphia: Lippincott Williams and Wilkins, 2009; 444-65
23. Hendrickx JF, Eger EI II, Sonner JM, Shafer SL: Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility. Anesth Analg, 2008; 107(2): 494-506
24. Giese JL, Stockham RJ, Stanley TH et al: Etomidate versus thiopental for induction of anesthesia. Anesth Analg, 1985; 64: 871-76
25. Doenicke AW, Roizen MF, Hoernecke R et al: Solvent for etomidate may cause pain and adverse effects. Br J Anesth, 1999; 83(3): 464-66