Lipopolysaccharide inhibits the self-renewal of spermatogonial stem cells in vitro via downregulation of GDNF expression in Sertoli cells

Reproductive Toxicology

Volumn 45, Issue , 2014, Pages 87-93

  Zhang, Xiaoli ^a   Shi, Kun ^a   Li, Yi ^b   Zhang, Haiyu ^a   Hao, Jing ^a  

^a SHANDONG UNIVERSITY   (China)

^b Zibo Maternal and Child Health Hospital   (China)

Author keywords

Differentiation; GDNF; LPS; Self renewal; Sertoli cells; Spermatogonial stem cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CYCLINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LIPOPOLYSACCHARIDE; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; VIMENTIN; BCL6B PROTEIN, MOUSE; DNA BINDING PROTEIN; ETV5 PROTEIN, MOUSE; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BCL6B GENE; BMP4 GENE; CELL ISOLATION; CELL RENEWAL; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; EMBRYO; ETV5 GENE; FEMALE; GAPDH GENE; GDNF GENE; GENE; GENE EXPRESSION REGULATION; GENE TARGETING; IN VITRO STUDY; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; OCT4 GENE; ONCOGENE C KIT; PLZF GENE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCF GENE; SERTOLI CELL; SOHLH2 GENE; SPERMATOGOINIAL STEM CELL; SPERMATOZOON COUNT; STEM CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; SPERMATOGONIUM;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; DOWN-REGULATION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; LIPOPOLYSACCHARIDES; MALE; MICE; REPRESSOR PROTEINS; RNA, MESSENGER; SERTOLI CELLS; SPERMATOGONIA; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 84896711846     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2014.01.009     Document Type: Article

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