Bad medicine: Nalmefene in alcohol misuse

BMJ (Online)

Volumn 348, Issue , 2014, Pages

  Spence, Des ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

NALMEFENE; NALTREXONE; PLACEBO;

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ALCOHOLISM; COST EFFECTIVENESS ANALYSIS; DATA ANALYSIS; DRINKING BEHAVIOR; DRUG APPROVAL; DRUG COST; DRUG RESEARCH; HUMAN; LIVER FUNCTION TEST; MEDICAL RESEARCH; NOTE; PATIENT COUNSELING; PRIORITY JOURNAL; TREATMENT OUTCOME; UNITED KINGDOM;

ALCOHOL DRINKING; ALCOHOLISM; HUMANS; NALTREXONE; NARCOTIC ANTAGONISTS; NEUROPROTECTIVE AGENTS;

EID: 84896709860     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.g1531     Document Type: Note

References (9)

1. Scottish Medicines Consortium. Nalmefene 18 mg film-coated tablets (Selincro®). 2013. www.scottishmedicines.org.uk/files/advice/nalmefene- Selincro-FINAL-September-2013- website.pdf.
2. National Institute for Health and Care Excellence. Single technology appraisal. Nalmefene for reducing alcohol consumption in people with alcohol dependence. 2014. www.nice.org.uk/nicemedia/live/14317/66222/66222.pdf.
3. Gual A, ESENSE 2 Study Group. A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence. Eur Neuropsychopharmacol 2013;23: 1432-42.
4. Mann K, Bladström A, Torup L, Gual A, van den Brink W. Extending the treatment options in alcohol dependence: a randomized controlled study of as-needed nalmefene. Biol Psychiatry 2013;73: 706-13.
5. Safety and efficacy of nalmefene in patients with alcohol dependence (SENSE). http://clinicaltrials.gov/ct2/show/results/NCT00811941?term= Sense+nalmefene&rank=1& sect=Xd8k96015#outcome8.
6. Van den Brink W, Aubin HJ, Bladström A, Torup L, Gual A, Mann K. Efficacy of as-needed nalmefene in alcohol-dependent patients with at least a high drinking risk level: results from a subgroup analysis of two randomized controlled 6-month studies. Alcohol Alcohol 2013;48: 570-8.
7. Boniface S, Shelton N. How is alcohol consumption affected if we account for under-reporting? A hypothetical scenario. Eur J Public Health 2013;23: 1076-81.
8. Nalmefene. British National Formulary. 2014. www.medicinescomplete.com/ mc/bnf/current/PHP33535-nalmefene.htm.
9. McAvoy BR. Naltrexone effective for alcohol dependence. Cochrane Primary Health Care Field 2010. www.cochraneprimarycare.org/pearls/naltrexone-effective- alcohol-dependence.