Histopathology of streptococcus mitis/oralis endophthalmitis after intravitreal injection with bevacizumab: A report of 7 patients

Ophthalmology

Volumn 121, Issue 3, 2014, Pages 702-708

  Matthews, Jared L ^a   Dubovy, Sander R ^a   Goldberg, Roger A ^a   Flynn, Harry W ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB;

AGED; ARTICLE; ATROPHY; BACTERIUM IDENTIFICATION; CENTRAL RETINA VEIN OCCLUSION; CHOROIDITIS; CILIARY DISK; CLINICAL ARTICLE; CLINICAL STUDY; CLOSED ANGLE GLAUCOMA; CORNEA INJURY; DESCEMET MEMBRANE; ENDOPHTHALMITIS; ENUCLEATION; EPIDEMIC; EYE SURGERY; FEMALE; GLIOSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPHEMA; HYPOPYON; IRIS RUBEOSIS; IRITIS; LENS; MALE; MEMBRANE FORMATION; MICROSCOPY; NEOVASCULAR GLAUCOMA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA CYSTOID EDEMA; RETINA NECROSIS; RETROSPECTIVE STUDY; SCAR FORMATION; STREPTOCOCCUS INFECTION; STREPTOCOCCUS MITIS; STREPTOCOCCUS ORALIS; SUBRETINAL FLUID; TISSUE CULTURE; TISSUE INJURY; VERY ELDERLY; VISUAL ACUITY; VITRECTOMY; VITREORETINOPATHY; VITREOUS BODY; VITRITIS;

AGED; AGED, 80 AND OVER; ANGIOGENESIS INHIBITORS; ANTI-BACTERIAL AGENTS; ANTIBODIES, MONOCLONAL, HUMANIZED; DISEASE OUTBREAKS; DRUG COMPOUNDING; ENDOPHTHALMITIS; EYE ENUCLEATION; EYE INFECTIONS, BACTERIAL; FEMALE; HUMANS; INTRAVITREAL INJECTIONS; MACULAR DEGENERATION; MACULAR EDEMA; MALE; RETROSPECTIVE STUDIES; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS MITIS; STREPTOCOCCUS ORALIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY; VITREOUS BODY;

EID: 84896706349     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2013.10.015     Document Type: Article

References (25)

1. A.A. Moshfeghi Endophthalmitis following intravitreal anti-vascular endothelial growth factor injections for neovascular age-related macular degeneration Semin Ophthalmol 26 2011 139 148
2. C.A. McCannel Meta-analysis of endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents: causative organisms and possible prevention strategies Retina 31 2011 654 661
3. Microbiologic factors and visual outcome in the Endophthalmitis Vitrectomy Study Am J Ophthalmol 122 1996 830 846
4. A. Moshfeghi, P.J. Rosenfeld, and H.W. Flynn Jr. et al. Endophthalmitis after intravitreal vascular endothelial growth factor antagonists: a six-year experience at a university referral center Retina 31 2011 662 668
5. R.A. Goldberg, H.W. Flynn Jr., and R.F. Isom et al. An outbreak of Streptococcus endophthalmitis after intravitreal injection of bevacizumab Am J Ophthalmol 153 2012 204 208
6. C.P. Shah, S.J. Garg, and J.F. Vander et al. Outcomes and risk factors associated with endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents Ophthalmology 118 2011 2028 2034
7. L.K. Mao, H.W. Flynn Jr., D. Miller, and S.C. Pflugfelder Endophthalmitis caused by streptococcal species Arch Ophthalmol 110 1992 798 801
8. G.M. Bohigian, and R.J. Olk Factors associated with a poor visual result in endophthalmitis Am J Ophthalmol 101 1986 332 341
9. Z.I. Carrim, J. Richardson, and W.N. Wykes Incidence and visual outcome of acute endophthalmitis after cataract surgery-the experience of an eye department in Scotland Br J Ophthalmol 93 2009 721 725
10. S. Jones, E.J. Cohen, J.J. Arentsen, and P.R. Laibson Ocular streptococcal infections Cornea 7 1988 295 299
11. R.A. Goldberg, H.W. Flynn Jr., and D. Miller et al. Streptococcus endophthalmitis outbreak after intravitreal injection of bevacizumab: one-year outcomes and investigative results Ophthalmology 120 2013 1448 1453
12. T. Wilemon Hospital gave tainted shots The Tennessean 1B August 7, 2011 5B
13. Pollack A. Five more reports of Avastin injections causing blindness. The New York Times. September 1, 2011. Available at: http://www.nytimes.com/2011/ 09/02/business/more-reports-of-avastin-causing-blindness.html?-r=0. Accessed January 3, 2013.
14. X. Sun, X. Xu, and X. Zhang Counterfeit bevacizumab and endophthalmitis [letter] N Engl J Med 365 2011 378 379 author reply 379
15. J.W. Cheng, and R.L. Wei Ranibizumab for age-related macular degeneration [letter] N Engl J Med 364 2011 582
16. S. Lee, S. Woo, and K. Park et al. Serratia marcescens endophthalmitis associated with intravitreal injections of bevacizumab Eye (Lond) 24 2010 226 232
17. S.A. Harrison, and J.B. Bateman Endogenous endophthalmitis caused by Streptococcus mitis Am J Ophthalmol 123 1997 260 261
18. P. Rai, R. Newsom, K. Mireskandari, and D. McHugh Endophthalmitis following globe perforation with a hypodermic needle [letter] Br J Ophthalmol 84 2000 799
19. E. Chen, A.C. Ho, and S.J. Garg et al. Streptococcus mitis endophthalmitis presenting as frosted branch angiitis after intravitreal pegaptanib sodium injection Ophthalmic Surg Lasers Imaging 40 2009 192 194
20. D.R. Fintak, G.K. Shah, and K.J. Blinder et al. Incidence of endophthalmitis related to intravitreal injection of bevacizumab and ranibizumab Retina 28 2008 1395 1399
21. M. Barza, P.R. Pavan, and B.H. Doft et al. Endophthalmitis Vitrectomy Study Group. Evaluation of microbiological diagnostic techniques in postoperative endophthalmitis in the Endophthalmitis Vitrectomy Study Arch Ophthalmol 115 1997 1142 1150
22. C.W. Douglas, J. Heath, K.K. Hampton, and F.E. Preston Identity of viridans streptococci isolated from cases of infective endocarditis J Med Microbiol 39 1993 179 182
23. D. Beighton, A.D. Carr, and B.A. Oppenheim Identification of viridans streptococci associated with bacteraemia in neutropenic cancer patients J Med Microbiol 40 1994 202 204
24. J. Mitchell Streptococcus mitis: walking the line between commensalism and pathogenesis Mol Oral Microbiol 26 2011 89 98
25. R. Forster Experimental postoperative endophthalmitis Trans Am Ophthalmol Soc 90 1992 505 559