Iridium-catalysed C-H borylation facilitates a total synthesis of the HRV 3C protease inhibitor (±)-thysanone

Synlett

Volumn 25, Issue 4, 2014, Pages 556-558

  Schünemann, Katrin ^a   Furkert, Daniel P ^a   Connelly, Stephen ^b   Fraser, John D ^a   Sperry, Jonathan ^a   Brimble, Margaret A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

CH activation; HRV 3C protease; oxa Pictet Spengler reaction; pyranonaphthoquinone; thysanone

Indexed keywords

ANTIVIRUS AGENT; CARBON; HYDROGEN; IRIDIUM; NATURAL PRODUCT; PROTEINASE; PROTEINASE INHIBITOR; PYRANONAPHTHOQUINONETHYSANONE; RESORCINOL DERIVATIVE; THYSANONE; UNCLASSIFIED DRUG;

ARTICLE; BORYLATION; CATALYSIS; CHEMICAL INTERACTION; CHEMICAL REACTION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN RHINOVIRUS; NONHUMAN;

EID: 84896703574     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0033-1340495     Document Type: Article

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