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Volumn 21, Issue 2, 2014, Pages 560-568

Overexpression of L1CAM is associated with tumor progression and prognosis via erk signaling in gastric cancer

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; L1 CELL ADHESION MOLECULE; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84896700381     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-013-3246-5     Document Type: Article
Times cited : (24)

References (33)
  • 1
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • 21296855 10.3322/caac.20107
    • Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin. 2011;61:69-90.
    • (2011) CA Cancer J Clin. , vol.61 , pp. 69-90
    • Jemal, A.1    Bray, F.2    Center, M.M.3
  • 2
    • 35748946650 scopus 로고    scopus 로고
    • Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine
    • 1:CAS:528:DC%2BD2sXht1Kit7bI 17978289 10.1056/NEJMoa072252
    • Sakuramoto S, Sasako M, Yamaguchi T, et al. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med. 2007;357:1810-20.
    • (2007) N Engl J Med. , vol.357 , pp. 1810-1820
    • Sakuramoto, S.1    Sasako, M.2    Yamaguchi, T.3
  • 3
    • 40749153540 scopus 로고    scopus 로고
    • S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial
    • 1:CAS:528:DC%2BD1cXivVaqtb4%3D 18282805 10.1016/S1470-2045(08)70035-4
    • Koizumi W, Narahara H, Hara T, et al. S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol. 2008;9:215-21.
    • (2008) Lancet Oncol. , vol.9 , pp. 215-221
    • Koizumi, W.1    Narahara, H.2    Hara, T.3
  • 4
    • 0023805739 scopus 로고
    • Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin
    • 1:CAS:528:DyaL1MXhs1ygu78%3D 3412448 10.1038/334701a0
    • Moos M, Tacke R, Scherer H, et al. Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature. 1988;334:701-3.
    • (1988) Nature. , vol.334 , pp. 701-703
    • Moos, M.1    Tacke, R.2    Scherer, H.3
  • 5
    • 0036024585 scopus 로고    scopus 로고
    • Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma
    • 1:CAS:528:DC%2BD38XmtVSmtLo%3D 12175686 10.1016/S0959-8049(02)00105-3
    • Thies A, Schachner M, Moll I, et al. Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma. Eur J Cancer. 2002;38:1708-16.
    • (2002) Eur J Cancer. , vol.38 , pp. 1708-1716
    • Thies, A.1    Schachner, M.2    Moll, I.3
  • 6
    • 0141518671 scopus 로고    scopus 로고
    • L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas
    • 1:CAS:528:DC%2BD3sXnt1alsbs%3D 13678974 10.1016/S0140-6736(03)14342-5
    • Fogel M, Gutwein P, Mechtersheimer S, et al. L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas. Lancet. 2003;362:869-75.
    • (2003) Lancet. , vol.362 , pp. 869-875
    • Fogel, M.1    Gutwein, P.2    Mechtersheimer, S.3
  • 7
    • 84864315091 scopus 로고    scopus 로고
    • Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-kappaB activation
    • 1:STN:280:DC%2BC38vgtVWntQ%3D%3D 22228447 10.1093/annonc/mdr568
    • Bondong S, Kiefel H, Hielscher T, et al. Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-kappaB activation. Ann Oncol. 2012;23:1795-802.
    • (2012) Ann Oncol. , vol.23 , pp. 1795-1802
    • Bondong, S.1    Kiefel, H.2    Hielscher, T.3
  • 8
    • 34249005587 scopus 로고    scopus 로고
    • L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer
    • 17211730 10.1245/s10434-006-9281-8
    • Boo Y-J, Park J-M, Kim J, et al. L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer. Ann Surg Oncol. 2007;14:1703-11.
    • (2007) Ann Surg Oncol. , vol.14 , pp. 1703-1711
    • Boo, Y.-J.1    Park, J.-M.2    Kim, J.3
  • 9
    • 80053615174 scopus 로고    scopus 로고
    • L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer
    • 1:CAS:528:DC%2BC3MXhsVSgs7fI 3198986 21985405 10.1186/1476-4598-10-127
    • Tischler V, Pfeifer M, Hausladen S, et al. L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer. Mol Cancer. 2011;10:127.
    • (2011) Mol Cancer. , vol.10 , pp. 127
    • Tischler, V.1    Pfeifer, M.2    Hausladen, S.3
  • 10
    • 13944268218 scopus 로고    scopus 로고
    • L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers
    • 1:CAS:528:DC%2BD2MXhsVCjsr8%3D 15716380 10.1083/jcb.200408051
    • Gavert N, Conacci-Sorrell M, Gast D, et al. L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers. J Cell Biol. 2005;168:633-42.
    • (2005) J Cell Biol. , vol.168 , pp. 633-642
    • Gavert, N.1    Conacci-Sorrell, M.2    Gast, D.3
  • 11
    • 33845807351 scopus 로고    scopus 로고
    • Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells
    • 1:CAS:528:DC%2BD28Xht1KnsL3M 17145883 10.1158/0008-5472.CAN-06-2106
    • Shtutman M, Levina E, Ohouo P, et al. Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells. Cancer Res. 2006;66:11370-80.
    • (2006) Cancer Res. , vol.66 , pp. 11370-11380
    • Shtutman, M.1    Levina, E.2    Ohouo, P.3
  • 12
    • 0033621478 scopus 로고    scopus 로고
    • Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization
    • 1:CAS:528:DC%2BD3cXkt1GlsA%3D%3D 10608864 10.1074/jbc.274.53.37965
    • Schaefer AW, Kamiguchi H, Wong EV, et al. Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization. J Biol Chem. 1999;274:37965-73.
    • (1999) J Biol Chem. , vol.274 , pp. 37965-37973
    • Schaefer, A.W.1    Kamiguchi, H.2    Wong, E.V.3
  • 13
    • 3142733866 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion
    • 1:CAS:528:DC%2BD2cXlsVCnsbs%3D 15128735 10.1074/jbc.M404075200
    • Silletti S, Yebra M, Perez B, et al. Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion. J Biol Chem. 2004;279:28880-8.
    • (2004) J Biol Chem. , vol.279 , pp. 28880-28888
    • Silletti, S.1    Yebra, M.2    Perez, B.3
  • 14
    • 23844476742 scopus 로고    scopus 로고
    • RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation
    • 1:CAS:528:DC%2BD2MXpsFClt7g%3D 2424128 16000162 10.1111/j.1471-4159.2005. 03254.x
    • Cheng L, Lemmon S, Lemmon V. RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation. J Neurochem. 2005;94:1102-10.
    • (2005) J Neurochem. , vol.94 , pp. 1102-1110
    • Cheng, L.1    Lemmon, S.2    Lemmon, V.3
  • 15
    • 0029925720 scopus 로고    scopus 로고
    • Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion
    • 1:CAS:528:DyaK28XhsFGntLs%3D 8640837
    • Izumoto S, Ohnishi T, Arita N, et al. Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res. 1996;56:1440-4.
    • (1996) Cancer Res. , vol.56 , pp. 1440-1444
    • Izumoto, S.1    Ohnishi, T.2    Arita, N.3
  • 16
    • 13244290151 scopus 로고    scopus 로고
    • Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: Important role of neural cell adhesion molecule L1 in tumour invasion
    • 1:CAS:528:DC%2BD2MXhvFCqu7s%3D 15677537 10.1136/jcp.2004.020909
    • Suzuki T, Izumoto S, Fujimoto Y, et al. Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion. J Clin Pathol. 2005;58:166-71.
    • (2005) J Clin Pathol. , vol.58 , pp. 166-171
    • Suzuki, T.1    Izumoto, S.2    Fujimoto, Y.3
  • 17
    • 33846558132 scopus 로고    scopus 로고
    • L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells
    • 1:CAS:528:DC%2BD2sXpvVKiuw%3D%3D 10.1016/j.ygyno.2006.08.038
    • Stoeck A, Gast D, Sanderson MP, et al. L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells. Gynecologic Oncol. 2007; 104:461-9.
    • (2007) Gynecologic Oncol. , vol.104 , pp. 461-469
    • Stoeck, A.1    Gast, D.2    Sanderson, M.P.3
  • 18
    • 77950219274 scopus 로고    scopus 로고
    • Therapeutic antibodies to human L1CAM: Functional characterization and application in a mouse model for ovarian carcinoma
    • 1:CAS:528:DC%2BC3cXjtFygtbY%3D 20215505 10.1158/0008-5472.CAN-09-3730
    • Wolterink S, Moldenhauer G, Fogel M, et al. Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer Res. 2010; 70:2504-15.
    • (2010) Cancer Res. , vol.70 , pp. 2504-2515
    • Wolterink, S.1    Moldenhauer, G.2    Fogel, M.3
  • 19
    • 34548015630 scopus 로고    scopus 로고
    • Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis
    • 1:CAS:528:DC%2BD2sXptVGlsb0%3D 17699774 10.1158/0008-5472.CAN-07-0991
    • Gavert N. Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis. Cancer Res. 2007;67:7703-12.
    • (2007) Cancer Res. , vol.67 , pp. 7703-7712
    • Gavert, N.1
  • 20
    • 33745478818 scopus 로고    scopus 로고
    • The adhesion molecule L1 (CD171) promotes melanoma progression
    • 1:CAS:528:DC%2BD28XmtlyjsrY%3D 16506207 10.1002/ijc.21880
    • Meier F, Busch S, Gast D, et al. The adhesion molecule L1 (CD171) promotes melanoma progression. Int J Cancer. 2006;119:549-55.
    • (2006) Int J Cancer. , vol.119 , pp. 549-555
    • Meier, F.1    Busch, S.2    Gast, D.3
  • 21
    • 66249104020 scopus 로고    scopus 로고
    • Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: Role in malignant transformation of pancreatic cancer
    • 1:CAS:528:DC%2BD1MXlvFWlu70%3D 19435915 10.1158/0008-5472.CAN-08-3493
    • Geismann C, Morscheck M, Koch D, et al. Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer. Cancer Res. 2009;69:4517-26.
    • (2009) Cancer Res. , vol.69 , pp. 4517-4526
    • Geismann, C.1    Morscheck, M.2    Koch, D.3
  • 22
    • 34247483148 scopus 로고    scopus 로고
    • Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells
    • Sebens Muerkoster S, Werbing V, Sipos B, et al. Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells. Oncogene. 2007;26:2759-68.
    • (2007) Oncogene , vol.26 , pp. 2759-2768
    • Sebens Muerkoster, S.1    Werbing, V.2    Sipos, B.3
  • 23
    • 71949100682 scopus 로고    scopus 로고
    • Expression of L1 cell adhesion molecule is a significant prognostic factor in pT3-stage gastric cancer
    • 19846947
    • Kodera Y, Nakanishi H, Ito S, et al. Expression of L1 cell adhesion molecule is a significant prognostic factor in pT3-stage gastric cancer. Anticancer Res. 2009;29:4033-9.
    • (2009) Anticancer Res. , vol.29 , pp. 4033-4039
    • Kodera, Y.1    Nakanishi, H.2    Ito, S.3
  • 24
    • 67650002410 scopus 로고    scopus 로고
    • L1 cell adhesion molecule (L1CAM) in invasive tumors
    • 1:CAS:528:DC%2BD1MXosVajurk%3D 19144458 10.1016/j.canlet.2008.12.021
    • Raveh S, Gavert N, Ben-Ze'ev A. L1 cell adhesion molecule (L1CAM) in invasive tumors. Cancer Lett. 2009;282:137-45.
    • (2009) Cancer Lett. , vol.282 , pp. 137-145
    • Raveh, S.1    Gavert, N.2    Ben-Ze'Ev, A.3
  • 25
    • 68249120305 scopus 로고    scopus 로고
    • L1 cell adhesion molecules as regulators of tumor cell invasiveness
    • 19483471 10.4161/cam.3.3.8689
    • Siesser PF, Maness PF. L1 cell adhesion molecules as regulators of tumor cell invasiveness. Cell Adh Migr. 2009;3:275-7.
    • (2009) Cell Adh Migr. , vol.3 , pp. 275-277
    • Siesser, P.F.1    Maness, P.F.2
  • 26
    • 84859395001 scopus 로고    scopus 로고
    • L1 cell adhesion molecule promotes tumorigenicity and metastatic potential in non-small cell lung cancer
    • 1:CAS:528:DC%2BC38XkvFOmu7o%3D 22307136 10.1158/1078-0432.CCR-11-2893
    • Hai J, Zhu C-Q, Bandarchi B, et al. L1 cell adhesion molecule promotes tumorigenicity and metastatic potential in non-small cell lung cancer. Clin Cancer Res. 2012;18:1914-24.
    • (2012) Clin Cancer Res. , vol.18 , pp. 1914-1924
    • Hai, J.1    Zhu, C.-Q.2    Bandarchi, B.3
  • 28
    • 33646399160 scopus 로고    scopus 로고
    • Targeting the ERK signaling pathway in cancer therapy
    • 1:CAS:528:DC%2BD28XktVyms7c%3D 16720434 10.1080/07853890600551037
    • Kohno M, Pouyssegur J. Targeting the ERK signaling pathway in cancer therapy. Ann Med. 2006;38:200-11.
    • (2006) Ann Med. , vol.38 , pp. 200-211
    • Kohno, M.1    Pouyssegur, J.2
  • 29
    • 77953566942 scopus 로고    scopus 로고
    • Nuclear factor-kappa B signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells
    • 10.1242/jcs.069542
    • Gavert N, Ben-Shmuel A, Lemmon V, et al. Nuclear factor-kappa B signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells. J Cell Sci. 2010;123:2134-42.
    • (2010) J Cell Sci. , vol.123 , pp. 2134-2142
    • Gavert, N.1    Ben-Shmuel, A.2    Lemmon, V.3
  • 30
    • 0029845321 scopus 로고    scopus 로고
    • L1 adhesion molecule on human lymphocytes and monocytes: Expression and involvement in binding to alpha v beta 3 integrin
    • 1:CAS:528:DyaK28XmsV2nsLc%3D 8898967 10.1002/eji.1830261035
    • Ebeling O, Duczmal A, Aigner S, et al. L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to alpha v beta 3 integrin. Eur J Immunol. 1996;26:2508-16.
    • (1996) Eur J Immunol. , vol.26 , pp. 2508-2516
    • Ebeling, O.1    Duczmal, A.2    Aigner, S.3
  • 31
    • 31544439090 scopus 로고    scopus 로고
    • Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment
    • 1:CAS:528:DC%2BD28XlsFOqug%3D%3D 16424028 10.1158/0008-5472.CAN-05-1818
    • Arlt MJE, Novak-Hofer I, Gast D, et al. Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment. Cancer Res. 2006;66:936-43.
    • (2006) Cancer Res. , vol.66 , pp. 936-943
    • Arlt, M.J.E.1    Novak-Hofer, I.2    Gast, D.3
  • 32
    • 39749174412 scopus 로고    scopus 로고
    • The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies
    • 1:CAS:528:DC%2BD1cXit1ymsLo%3D 17952127 10.1038/sj.onc.1210747
    • Gast D, Riedle S, Issa Y, et al. The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies. Oncogene. 2008;27:1281-9.
    • (2008) Oncogene. , vol.27 , pp. 1281-1289
    • Gast, D.1    Riedle, S.2    Issa, Y.3
  • 33
    • 84858069821 scopus 로고    scopus 로고
    • Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma
    • 22210381 10.1016/j.canlet.2011.12.035
    • Schafer H, Dieckmann C, Korniienko O, et al. Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma. Cancer Lett. 2012;319:66-82.
    • (2012) Cancer Lett. , vol.319 , pp. 66-82
    • Schafer, H.1    Dieckmann, C.2    Korniienko, O.3


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