25-hydroxyvitamin D concentrations in children with Crohn's disease supplemented with either 2000 or 400 IU daily for 6 months: A randomized controlled study

Journal of Pediatrics

Volumn 164, Issue 4, 2014, Pages 860-865

  Wingate, Kirstin E ^a   Jacobson, Kevan ^a   Issenman, Robert ^b   Carroll, Matthew ^a   Barker, Collin ^a   Israel, David ^a   Brill, Herbert ^b   Weiler, Hope ^c   Barr, Susan I ^a   Li, Wangyang ^a   Lyon, Michael R ^d   Green, Timothy J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d Canadian Center for Functional Medicine   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; C REACTIVE PROTEIN; COLECALCIFEROL; IMMUNOMODULATING AGENT; MESALAZINE;

ADOLESCENT; ADULT; ARTICLE; BODY MASS; CALCIUM BLOOD LEVEL; CHILD; CONTROLLED STUDY; CROHN DISEASE; CROHN DISEASE ACTIVITY INDEX; DIET SUPPLEMENTATION; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE SEDIMENTATION RATE; HUMAN; MAJOR CLINICAL STUDY; PHOSPHATE BLOOD LEVEL; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; YOUNG ADULT;

ADOLESCENT; CHILD; CROHN DISEASE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; TIME FACTORS; VITAMIN D;

EID: 84896549395     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2013.11.071     Document Type: Article

References (27)

1. B.P. Abraham, S. Mehta, and H.B. El-Serag Natural history of pediatric-onset inflammatory bowel disease J Clin Gastroenterol 46 2012 581 589
2. K. Gerasimidis, P. McGrogan, and C.A. Edwards The aetiology and impact of malnutrition in paediatric inflammatory bowel disease J Hum Nutr Diet 24 2011 313 326
3. S.R. Glick, and R.S. Carvalho Inflammatory bowel disease Pediatr Rev 32 2011 14 24
4. C.N. Bernstein, W.D. Leslie, and M.S. Leboff AGA technical review on osteoporosis in gastrointestinal diseases Gastroenterology 124 2003 795 841 (Pubitemid 36268496)
5. R. Gokhale, M.J. Favus, T. Karrison, M.M. Sutton, B. Rich, and B.S. Kirschner Bone mineral density assessment in children with inflammatory bowel disease Gastroenterology 114 1998 902 911 (Pubitemid 28217555)
6. S. Bechtold, M. Alberer, T. Arenz, S. Putzker, B. Filipiak-Pittroff, and H.P. Schwarz et al. Reduced muscle mass and bone size in pediatric patients with inflammatory bowel disease Inflamm Bowel Dis 16 2010 216 225
7. S. Laakso, H. Valta, M. Verkasalo, S. Toiviainen-Salo, H. Viljakainen, and O. Mäkitie Impaired bone health in inflammatory bowel disease: a case-control study in 80 pediatric patients Calcif Tissue Int 91 2012 121 130
8. S.E. Dubner, J. Shults, R.N. Baldassano, B.S. Zemel, M. Thayu, and J.M. Burnham et al. Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease Gastroenterology 136 2009 123 130
9. W.-C. Lim, S.B. Hanauer, and Y.C. Li Mechanisms of disease: vitamin D and inflammatory bowel disease Nat Clin Pract Gastroenterol Hepatol 2 2005 308 315 (Pubitemid 41102862)
10. M.T. Cantorna Vitamin D, multiple sclerosis and inflammatory bowel disease Arch Biochem Biophys 523 2012 103 106
11. D. Bruce, S. Yu, J.H. Ooi, and M.T. Cantorna Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling Int Immunol 23 2011 519 528
12. E.V. Loftus Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences Gastroenterology 126 2004 1504 1517 (Pubitemid 38649869)
13. V. Pinsk, D.A. Lemberg, K. Grewal, C.C. Barker, R.A. Schreiber, and K. Jacobson Inflammatory bowel disease in the South Asian pediatric population of British Columbia Am J Gastroenterol 102 2007 1077 1083 (Pubitemid 46698231)
14. M.T. Cantorna, C. Munsick, C. Bemiss, and B.D. Mahon 1,25- dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease J Nutr 130 2000 2648 2652
15. 3 treatment in Crohn's disease - a randomized double-blind placebo-controlled study Alimen Pharmacol Ther 32 2010 377 383
16. H.A. Bischoff-Ferrari, E. Giovannucci, W.C. Willett, T. Dietrich, and B. Dawson-Hughes Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes Am J Clin Nutr 84 2006 18 28 (Pubitemid 44699167)
17. H.M. Pappa, P.D. Mitchell, H. Jiang, S. Kassiff, R. Filip-Dhima, and D. DiFabio et al. Treatment of vitamin D insufficiency in children and adolescents with inflammatory bowel disease: a randomized clinical trial comparing three regimens J Clin Endocrinol Metab 97 2012 2134 2142
18. Institute of Medicine Dietary references intakes for calcium and vitamin D 2011 National Academy Press Washington, DC
19. J.S. Hyams, G.D. Ferry, F.S. Mandel, J.D. Gryboski, P.M. Kibort, and B.S. Kirschner et al. Development and validation of a pediatric Crohn's disease activity index J Pediatr Gastroenterol Nutr 12 1991 439 447
20. A. Otley, H. Loonen, N. Parekh, M. Corey, P.M. Sherman, and A.M. Griffiths Assessing activity of pediatric Crohn's disease: which index to use? Gastroenterology 116 1999 527 531 (Pubitemid 29106759)
21. Institute of Medicine Dietary reference intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride 1997 National Academy Press Washington, DC
22. H. Wu, A. Gozdzik, J.L. Barta, D. Wagner, D.E. Cole, and R. Vieth et al. The development and evaluation of a food frequency questionnaire used in assessing vitamin D intake in a sample of healthy young Canadian adults of diverse ancestry Nutr Res 29 2009 255 261
23. W. El-Matary, S. Sikora, and D. Spady Bone mineral density, vitamin D, and disease activity in children newly diagnosed with inflammatory bowel disease Dig Dis Sci 56 2011 825 829
24. A. Cranney, H.A. Weiler, S. O'Donnell, and L. Puil Summary of evidence-based review on vitamin D efficacy and safety in relation to bone health Am J Clin Nutr 88 2008 513S 519S
25. K. Langlois, L. Greene-Finestone, J. Little, N. Hidiroglou, and S. Whiting Vitamin D status of Canadians as measured in the 2007 to 2009 Canadian Health Measures Survey Health Rep 21 2010 47 55
26. L. Yang, V. Weaver, J.P. Smith, S. Bingaman, T.J. Hartman, and M.T. Cantorna Therapeutic effect of vitamin D supplementation in a pilot study of Crohn's patients Clin Trans Gastroenterol 4 2013 e33
27. R.P. Heaney, K.M. Davies, T.C. Chen, M.F. Holick, and M.J. Barger-Lux Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol Am J Clin Nutr 77 2003 204 210 (Pubitemid 36015393)