Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase γ (POLG1)

BMJ Case Reports

Volumn , Issue , 2009, Pages

  McFarland, R ^a   Hudson, G ^b   Taylor, R W ^b   Green, S H ^c   Hodges, S ^a   McKiernan, P J ^c   Chinnery, P F ^a,b   Ramesh, V ^a  

^a NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84896540600     PISSN: None     EISSN: 1757790X     Source Type: Journal    
DOI: 10.1136/bcr.12.2008.1303     Document Type: Article

References (13)

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4. Spinazzola A, Viscomi C, Fernandez-Vizarra E, et al. MPV17 encodes an inner mitochondrial membrane protein and is mutated in inf antile hepatic mitochondrial DNA depletion. Nat Genet 2006; 38: 570-5.
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12. Chan SS, Longley MJ, Copeland WC. Modulation of the W748S mutation in DNA poly merase gamma by the E1143G poly morphism in mitochondrial disorders. Hum Mol Genet 2006; 15: 3473-83. (Pubitemid 44811599)
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