Using flow cytometry to detect haemic neoplasia in mussels (Mytilus trossulus) from the Pacific Coast of Southern British Columbia, Canada

Journal of Invertebrate Pathology

Volumn 117, Issue 1, 2014, Pages 68-72

  Vassilenko, Ekaterina ^a   Baldwin, Susan A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Biomonitoring; Flow cytometry; Haemic neoplasia; Mussel leukemia; Mytilus trossulus; Ploidy

Indexed keywords

ANIMAL; BLOOD CELL; CANADA; FLOW CYTOMETRY; MYTILUS; PATHOLOGY; PLOIDY; PROCEDURES;

ANIMALS; BRITISH COLUMBIA; FLOW CYTOMETRY; HEMOCYTES; MYTILUS; PLOIDIES;

EID: 84896523599     PISSN: 00222011     EISSN: 10960805     Source Type: Journal    
DOI: 10.1016/j.jip.2014.02.002     Document Type: Article

References (23)

1. Allam B., Ashton-Alcox K.A., Ford S.E. Flow cytometric comparison of haemocytes from three species of bivalve molluscs. Fish Shellfish Immun. 2002, 13:141-158.
2. Barber B. Neoplastic diseases of commercially important marine bivalves. Aquat. Living Resour. 2004, 17:449-466.
3. Barlogie B., Stass S., Dixon D., Keating M., Cork A., Trujillo J.M., McCredie K.B., Freireich E.J. DNA aneuploidy in adult acute leukemia. Cancer Genet. Cytogenet. 1987, 28:213-228.
4. Bihari N., Micic M., Batel R., Zahn R.K. Flow cytometric detection of DNA cell cycle alterations in hemocytes of mussels (Mytilus galloprovincialis) off the Adriatic coast. Croatia. Aquat. Toxicol. 2003, 64:121-129.
5. Bower S. The summer mortality syndrome and haemic neoplasia in the blue mussels (Mytilus edulis) from British Columbia. Can. Tech. Rep. Fisheries Aquat. Sci. 1989, 1703:1-65.
6. Bower, S., 2006. Synopsis of Infectious Diseases and Parasites of Commercially Exploited Shellfish: Haemocytic Neoplasia of Mussels. http://www.pac.dfo-mpo.gc.ca/science/species-especes/shellfish-coquillages/diseases-maladies/pages/hcnmu-eng.htm.
7. da Silva P.M., Soudant P., Carballal M.J., Lambert C., Villalba A. Flow cytometric DNA content analysis of neoplastic cells in haemolymph of the cockle Cerastoderma edule. Dis. Aquat. Organ. 2005, 67:133-139.
8. Delaporte M., Synard S., Pariseau J., McKenna P., Tremblay R., Davidson J., Berthe F.C. Assessment of haemic neoplasia in different soft shell clam Mya arenaria populations from eastern Canada by flow cytometry. J. Invertebr. Pathol. 2008, 98:190-197.
9. Diaz S., Villalba A., Insua A., Soudant P., Fernandez-Tajes J., Mendez J., Carballal M.J. Disseminated neoplasia causes changes in ploidy and apoptosis frequency in cockles Cerastoderma edule. J. Invertebr. Pathol. 2011, 113:214-219.
10. Elston R.A., Drum A.S., Allen S.K. Progressive development of circulating polyploid cells in Mytilus with hemic neoplasia. Dis. Aquat. Organ. 1990, 8:51-59.
11. Elston R.A., Moore J.D., Brooks K. Disseminated neoplasia of bivalve mollusks. Rev. Aquat. Sci. 1992, 6:405-466.
12. Farley C.A. Sarcomatoid proliferative disease in a wild population of blue mussels (Mytilus edulis). J. Natl. Cancer I 1969, 43:509-516.
13. Gonzalez-Tizon A., Martinez-Lage A., Ausio J., Mendez J. Polyploidy in a natural population of mussel, Mytilus trossulus. Genome 2000, 43:409-411.
14. Gosling E. The Mussel Mytilus: Ecology, Physiology, Genetics, and Culture 1992, Elsevier, Amsterdam.
15. Le Grand F., Kraffe E., de Montaudouin X., Villalba A., Marty Y., Soudant P. Prevalence, intensity, and aneuploidy patterns of disseminated neoplasia in cockles (Cerastoderrna edule) from arcachon bay: seasonal variation and position in sediment. J. Invertebr. Pathol. 2011, 104:110-118.
16. Moore J.D., Elston R.A., Drum A.S., Wilkinson M.T. Alternate pathogenesis of systemic neoplasia in the bivalve mollusc Mytilus. J. Invertebr. Pathol. 1991, 58:231-243.
17. Rodríguez A.M., Torrado M., Mendéz J. Genome-size variation in bivalve molluscs determined by flow cytometry. Mar. Biol. 1996, 126:489-497.
18. Schmitt C.A., Fridman J.S., Yang M., Baranov E., Hoffman R.M., Lowe S.W. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell. 2002, 1:289-298.
19. Smolowitz R.M., Reinisch C.L. A novel adhesion protein expressed by ciliated epithelium, hemocytes, and leukemia cells in soft-shell clams. Dev. Comp. Immunol. 1993, 17:475-481.
20. Storchova Z., Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat. Rev. Mol. Cell Biol. 2004, 5:45-54.
21. Vassilenko E.I., Muttray A.F., Schulte P.M., Baldwin S.A. Variations in p53-like cDNA sequence are correlated with mussel haemic neoplasia: a potential molecular-level tool for biomonitoring. Mutat. Res. 2010, 701:145-152.
22. Viarengo A., Lowe D., Bolognesi C., Fabbri E., Koehler A. The use of biomarkers in biomonitoring: a 2-tier approach assessing the level of pollutant-induced stress syndrome in sentinel organisms. Compos. Biochem. Phys. C 2007, 146:281-300.
23. Yevich P.P., Barszcz C.A. Neoplasia in soft-shell clams (Mya arenaria) collected from oil-impacted sites. Ann. NY Acad. Sci. 1978, 298:409-426.