Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Nguyen, Linda ^a   Robson, Matthew J ^a   Healy, Jason R ^a   Scandinaro, Anna L ^a   Matsumoto, Rae R ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BD 1063; DEXTROMETHORPHAN; IMIPRAMINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; QUINIDINE; RECEPTOR BLOCKING AGENT; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; BINDING ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG POTENTIATION; DRUG RECEPTOR BINDING; FORCED SWIM TEST; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN FUNCTION;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLENEDIAMINES; EXCITATORY AMINO ACID ANTAGONISTS; KETAMINE; KINETICS; MALE; MICE; PIPERAZINES; PROTEIN BINDING; QUINIDINE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, SIGMA; SWIMMING;

EID: 84896522734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089985     Document Type: Article

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