Reply to Heng: Inborn aneuploidy and chromosomal instability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 11, 2014, Pages

  Valind, Anders ^a   Gisselsson, David ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; CANCER CELL CULTURE; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME NUMBER; CLONAL CHROMOSOME ABERRATION; DISEASE ASSOCIATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; HUMAN; LETTER; NONCLONAL CHROMOSOME ABERRATION; PHENOTYPE; PRIORITY JOURNAL;

ANEUPLOIDY; CHROMOSOMAL INSTABILITY; HUMANS; NEOPLASMS;

EID: 84896506370     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323978111     Document Type: Letter

References (6)

1. Heng HH (2014) Distinguishing constitutional and acquired nonclonal aneuploidy. Proc Natl Acad Sci USA 111:E972.
2. Valind A, Jin Y, Baldetorp B, Gisselsson D (2013) Whole chromosome gain does not in itself confer cancer-like chromosomal instability. Proc Natl Acad Sci USA 110(52):21119-21123.
3. Stingele S, et al. (2012) Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Mol Syst Biol 8:608.
4. Barber TD, et al. (2008) Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proc Natl Acad Sci USA 105(9):3443-3448. (Pubitemid 351723572)
5. Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83.
6. Valind A, Jin Y, Gisselsson D (2013) Elevated tolerance to aneuploidy in cancer cells: estimating the fitness effects of chromosome number alterations by in silico modelling of somatic genome evolution. PLoS ONE 8(7):e70445.