Overexpression of eukaryotic initiation factor 4e is correlated with increased risk for systemic dissemination in node-positive breast cancer patients

Journal of the American College of Surgeons

Volumn 218, Issue 4, 2014, Pages 663-671

  Yin, Xuedong ^a,b   Kim, Roger H ^a   Sun, Guang ^a   Miller, Janet K ^a   Li, Benjamin D ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E;

ADULT; ARTICLE; BONE METASTASIS; BRAIN METASTASIS; BREAST CANCER; CANCER PROGNOSIS; CANCER RECURRENCE; CARCINOGENESIS; CONTROLLED STUDY; FOLLOW UP; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HIGH RISK PATIENT; HUMAN; LIVER METASTASIS; LUNG METASTASIS; MAJOR CLINICAL STUDY; METASTASIS; MIDDLE AGED; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN CONTENT; SYSTEMIC DISEASE; SYSTEMIC METASTASIS; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; EUKARYOTIC INITIATION FACTOR-4E; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; PROSPECTIVE STUDIES; RISK; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84896488370     PISSN: 10727515     EISSN: 18791190     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2013.12.020     Document Type: Article

References (36)

1. A. Jemal, F. Bray, and M.M. Center et al. Global cancer statistics CA Cancer J Clin 61 2011 69 90
2. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics CA Cancer J Clin 63 2013 11 30
3. T. Sorlie, C.M. Perou, and R. Tibshirani et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci U S A 98 2001 10869 10874
4. C.L. Carter, C. Allen, and D.E. Henson Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases Cancer 63 1989 181 187
5. L.F. Hernandez-Aya, M. Chavez-Macgregor, and X. Lei et al. Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer J Clin Oncol 29 2011 2628 2634
6. R.E. Rhoads, S. Joshi-Barve, and C. Rinker-Schaeffer Mechanism of action and regulation of protein synthesis initiation factor 4E: effects of mRNA discrimination, cellular growth rate, and oncogenesis Prog Nucleic Acid Res Mol Biol 46 1993 183 219
7. N. Sonenberg, and A.C. Gingras The mRNA 5′ cap-binding protein eIF4E and control on cell growth Curr Opin Cell Biol 10 1998 268 275
8. A.E. Koromilas, A. Lazaris-Karatzas, and N. Sonenberg mRNAs containing extensive secondary structure in their 5′ non-coding region translate efficiently in cells overxpressing initiation factor 4E EMBO J 11 1992 4153 4159
9. I.B. Rosenwald, A. Lazaris-Karatzas, and N. Sonenberg et al. Elevated levels of cyclin D1 in response to increased expression of eukaryotic initiation factor 4E Mol Cell Biol 13 1993 7358 7563
10. C. Kevil, A. De Benedetti, and D.K. Payne et al. Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis Int J Cancer 65 1996 785 790
11. C. Kevil, P. Carter, B. Hu, and A. De Benedetti Translational enhancement of FGF-2 by eIF-4 factors, and alternate utilization of CUG and AUG codons for translation initiation Oncogene 11 1995 2339 2348
12. Y. Li, R. DeFatta, and C. Anthony et al. A translationally regulated tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed Oncogene 20 2001 726 738
13. A. De Benedetti, and A.L. Harris EIF4E expression in tumors: its possible role in progression of malignancies Int J Biochem Cell Biol 31 1999 59 72
14. V. Kerekatte, K. Smiley, and B. Hu et al. The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas Int J Cancer 64 1995 27 31
15. C.O. Nathan, L. Liu, and B.D.L. Li et al. Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer Oncogene 15 1997 579 584
16. H.J. Berkel, E.A. Turbat-Herrera, R. Shi, and A. De Benedetti Expression of the translation initiation factor eIF4E in the polyp-cancer sequence in the colon Cancer Epidemiol Biomarkers Prev 10 2001 663 666
17. B.D.L. Li, J.C. McDonald, and R. Nassar et al. Clinical outcome in stage I to III breast carcinoma and eIF4E overexpression Ann Surg 227 1998 756 763
18. B.D.L. Li, J.S. Gruner, and F. Abreo et al. Prospective study of eIF4E protein elevation and breast cancer outcome Ann Surg 235 2002 732 739
19. B.D.L. Li, D. McClusky, and R.H. Turnage et al. A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-positive breast cancer Ann Surg 242 2005 584 590
20. N.T. Holm, K. Byrnes, and L. Johnson et al. A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-negative breast cancer Ann Surg Oncol 15 2008 3207 3215
21. K. Byrnes, S. White, and Q. Chu et al. High eIF4E, VEGF, and microvessel density in stage I to III breast cancer Ann Surg 243 2006 684 692
22. M. Skobe, T. Hawighorst, and D.G. Jackson et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis Nat Med 7 2001 192 198
23. R.A. Mohammed, A. Green, and S. El-Shikh et al. Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angio- and lymphangiogenesis Br J Cancer 96 2007 1092 1100
24. N. Weidner, J. Semple, and J. Folkman Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma N Engl J Med 324 1991 1 8
25. J. Xu, S. Lamouille, and R. Derynck TGF-beta-induced epithelial to mesenchymal transition Cell Res 19 2009 156 172
26. A. Voulgari, and A. Pintzas Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic Biochim Biophys Acta 1796 2009 75 90
27. R. Karni, Y. Gus, and Y. Dor et al. Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation Mol Cell Biol 25 2005 5031 5039
28. S. Lamouille, and R. Derynck Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway J Cell Biol 178 2007 437 451
29. A.C. Hsieh, M. Costa, and O. Zollo et al. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E Cancer Cell 17 2010 249 261
30. B. Ghosh, A.O. Benyumov, and P. Ghosh et al. Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation ACS Chem Biol 4 2009 367 377
31. J. Shankar, A. Messenberg, and J. Chan et al. Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells Cancer Res 70 2010 3780 3790
32. G. Sunavala-Dossabhoy, S. Balakrishnan, and S. Sen et al. The radioresistance kinase TLK1B protects cells by promoting repair of double strand breaks BMC Mol Biol 6 2005 19 29
33. C. Canfield, J. Rains, and A. De Benedetti TLK1B promotes repair of DSBs via its interaction with Rad9 and ASF1 BMC Mol Biol 10 2009 110 123
34. K. Norton, D. McClusky, and A. De Benedetti et al. TLK1B is elevated with eIF4E overexpression in breast cancer J Surg Res 116 2004 98 103
35. R. Wolfort, A. De Benedetti, and S. Nuthalapaty et al. Up-regulation of TLK1B by eIF4E overexpression predicts cancer recurrence in irradiated patients with breast cancer Surgery 140 2006 161 169
36. K. Byrnes, A. De Benedetti, and N. Holm et al. Correlation of TLK1B elevation and recurrence in doxorubicin-treated breast cancer patients with high eIF4E overexpression J Am Coll Surg 204 2007 925 934