Trabeculectomy using mitomycin C versus an atelocollagen implant: Clinical results of a randomized trial and histopathologic findings

Ophthalmologica

Volumn 231, Issue 3, 2014, Pages 133-140

  Rosentreter, André ^a   Gaki, Stergiani ^a   Cursiefen, Claus ^a   Dietlein, Thomas S ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Atelocollagen; Biodegradable implant; Filtering bleb; Glaucoma; Mitomycin C; Ologen ; Trabeculectomy

Indexed keywords

ATELOCOLLAGEN; MITOMYCIN; DEXAMETHASONE; OFLOXACIN;

AGED; ALLERGY; ARTICLE; BIODEGRADABLE IMPLANT; CHOROID DETACHMENT; CLINICAL ARTICLE; CONTROLLED STUDY; EARLY HYPOTONY; FEMALE; FILTRATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPHEMA; INTERMETHOD COMPARISON; INTRAOCULAR PRESSURE; LATE HYPOTONY; LATE LEAKAGE; MALE; MORPHOLOGY; OPEN ANGLE GLAUCOMA; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); SHALLOW ANTERIOR CHAMBER; TRABECULECTOMY; WOUND HEALING; IMMUNOHISTOCHEMISTRY; INTERVENTION STUDY; NYLON SUTURE; POLYGLACTIN SUTURE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TOPICAL TREATMENT;

ABSORBABLE IMPLANTS; ACTINS; AGED; ALKYLATING AGENTS; COLLAGEN; COLLAGEN TYPE III; COMBINED MODALITY THERAPY; FEMALE; FIBRONECTINS; GLAUCOMA, OPEN-ANGLE; GLYCOSAMINOGLYCANS; HUMANS; INTRAOCULAR PRESSURE; MALE; MIDDLE AGED; MITOMYCIN; PROLYL HYDROXYLASES; PROSPECTIVE STUDIES; SURGICAL FLAPS; TONOMETRY, OCULAR; TRABECULECTOMY;

EID: 84896488110     PISSN: 00303755     EISSN: 14230267     Source Type: Journal    
DOI: 10.1159/000356400     Document Type: Article

References (27)

1. Addicks EM, Quigley HA, Green WR, Robin AL: Histologic characteristics of filtering blebs in glaucomatous eyes. Arch Ophthal-mol 1983; 101:795-798.
2. Hitchings RA, Grierson I: Clinicopathologi-cal correlation in eyes with failed fistulising surgery. Trans Ophthalmol Soc UK 1983; 103: 84-88.
3. The Fluorouracil Filtering Surgery Study Group: Five-year follow-up of the Fluoroura-cil Surgery Study. Am J Ophthalmol 1996; 121:349-366.
4. Katz GJ, Higginbotham EJ, Lichter PR, Skuta GL, Musch DC, Bergstrom TJ, Johnson AT: Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery: extended follow-up. Ophthalmology 1995; 102: 1263-1269.
5. Khaw PT, Doyle JW, Sherwood MB, Smith MF, McGorray S: Effects of intraoperative 5-fluorouracil or mitomycin-C on glaucoma filtration surgery in the rabbit. Ophthalmology 1993; 100:367-372.
6. Martini E, Laffi GL, Sprovieri C, Scorolli L: Low-dosage mitomycin C as an adjunct to trabeculectomy. A prospective controlled study. Eur J Ophthalmol 1997; 7: 40-48.
7. Khaw PT, Doyle JW, Sherwood MB, Grierson I, Schultz G, McGorray S: Prolonged localized tissue effects from 5-minute exposures to 5-fluorouracil and mitomycin C. Arch Oph-thalmol 1993; 111:263-267.
8. Mac I, Soltau JB: Glaucoma-filtering bleb infections. Curr Opin Ophthalmol 2003; 14:91-94.
9. Stamper RL, McMenemy MG, Lieberman MF: Hypotonous maculopathy after trabecu-lectomy with subconjunctival 5-fluorouracil. Am J Ophthalmol 1992; 114:544-553.
10. Hsu WC, Spilker MH, Yannas IV, Rubin PA: Inhibition of conjunctival scarring and contraction by a porous collagen-glycosamino-glycan implant. Invest Ophthalmol Vis Sci 2000; 41:2404-2411.
11. Chen HS, Ritch R, Krupin T, Hsu WC: Control of filtering bleb structure through tissue bioengineering: an animal model. Invest Opht halmol Vis Sci 2006; 47: 5310-5314.
12. Hsu WC, Ritch R, Krupin T, Chen HS: Tissue bioengineering for surgical bleb defects: an animal study. Graefes Arch Clin Exp Oph-thalmol 2008; 246:709-717.
13. Rosentreter A, Schild AM, Jordan JF, Kriegl-stein GK, Dietlein TS: A prospective randomised trial of trabeculectomy using mito-mycin C vs an Ologen implant in open angle glaucoma. Eye 2010; 24:1449-1457.
14. Papaconstantinou D, Georgalas I, Karmiris E, Diagourtas A, Koutsandrea C, Ladas I, Apos-tolopoulos M, Georgopoulos G: Trabeculec-tomy with Ologen versus trabeculectomy for the treatment of glaucoma: a pilot study. Acta Ophthalmol 2010; 88:80-85.
15. Stenzel KH, Miyata T, Rubin AL: Collagen as a biomaterial. Annu Rev Biophys Bioeng 1974; 3:231-253.
16. Klink T, Schrey S, Elsesser U, Klink J, Schlunck G, Grehn F: Interobserver variability of the Würzburg Bleb Classifiaction Score. Oph-thalmologica 2008; 222:408-413.
17. Rosentreter A, Dinslage S, Krieglstein GK, Dietlein TS: Intra-individual comparison after combined phaco-trabecular aspiration in pairs of pseudoexfoliative eyes. Graefes Arch Clin Exp Ophthalmol 2010; 248:79-83.
18. Cairns JE: Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol 1968; 66:673-679.
19. Wilkins M, Indar A, Wormald R: Intra-oper-ative mitomycin C for glaucoma surgery. Co-chrane Database Syst Rev 2005; 4:CD002897.
20. Reibaldi A, Uva MG, Longo A: Nine-year follow-up of trabeculectomy with or without low-dosage mitomycin C in primary open-angle-glaucoma. Br J Ophthalmol 2008; 92: 1666-1670.
21. Beckers HJ, Kinders KC, Webers CA: Five-year results of trabeculectomy with mitomy-cin C. Graefes Arch Clin Exp Ophthalmol 2003; 241:106-110.
22. Rosentreter A, Mellein AC, Konen WW, Di-etlein TS: Capsule excision and Ologen implantation for revision after glaucoma drainage device surgery. Graefes Arch Clin Exp Ophthalmol 2010; 248:1319-1324.
23. Cillino S, Di Pace F, Cillino G, Casuccio A: Biodegradable collagen matrix implant vs mi-tomycin-C as an adjuvant in trabeculectomy: a 24-month, randomized clinical trial. Eye 2011; 25:1598-1606.
24. Marey HM, Mandour SS, Ellakwa AF: Sub-scleral trabeculectomy with mitomycin-C versus Ologen for treatment of glaucoma. J Ocul Pharmacol Ther 2013; 29:330-334.
25. Narayanaswamy A, Perera SA, Htoon HM, Hoh ST, Seah SK, Wong TT, Aung T: Efficacy and safety of collagen matrix implants in phacotrabeculectomy and comparison with mitomycin C augmented phacotrabeculecto-my at 1 year. Clin Experiment Ophthalmol 2013; 41:552-560.
26. Min JK, Kee CW, Sohn SW, Lee HJ, Woo JM, Yim JH: Surgical outcome of mitomycin C-soaked collagen matrix implant in trabeculec-tomy. J Glaucoma 2013; 22:456-462.
27. Dada T, Kusumesh R, Bali SJ, Sharma S, Sob-ti A, Arora V, Panda A: Trabeculectomy with combined use of subconjunctival collagen implant and low-dose mitomycin C. J Glaucoma 2013; 22:659-662.