pACICU2 is a conjugative plasmid of Acinetobacter carrying the aminoglycoside resistance transposon TnaphA6

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 4, 2014, Pages 1146-1148

  Hamidian, Mohammad ^a   Hall, Ruth M ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Acinetobacter baumannii; Amikacin resistance; ISAba125; Resistance transfer

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; AMPICILLIN; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; GENTAMICIN; IMIPENEM; KANAMYCIN; MEROPENEM; NALIDIXIC ACID; NEOMYCIN; NETILMICIN; RIFAMPICIN; SPECTINOMYCIN; STREPTOMYCIN; SULFONAMIDE; SULTAMICILLIN; TETRACYCLINE; TIMENTIN; TOBRAMYCIN; TRIMETHOPRIM;

ACINETOBACTER; ANTIBIOTIC RESISTANCE; GENE SEQUENCE; LETTER; NONHUMAN; NUCLEOTIDE SEQUENCE; TRANSPOSON;

ACINETOBACTER BAUMANNII; AMIKACIN RESISTANCE; ISABA125; RESISTANCE TRANSFER;

ACINETOBACTER; ACINETOBACTER INFECTIONS; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CONJUGATION, GENETIC; DRUG RESISTANCE, BACTERIAL; GENE TRANSFER, HORIZONTAL; HUMANS; MICROBIAL SENSITIVITY TESTS; PLASMIDS;

EID: 84896461556     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt488     Document Type: Letter

References (9)

1. Lambert T, Gerbaud G, Bouvet P et al. Dissemination of amikacin resistance gene aphA6 in Acinetobacter spp. Antimicrob Agents Chemother 1990; 34: 1244-8.
2. Nemec A, Dolzani L, Brisse S et al. Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones. J Med Microbiol 2004; 53: 1233-40.
3. Nigro SJ, Post V, Hall RM. Aminoglycoside resistance in multiply antibiotic-resistant Acinetobacter baumannii belonging to global clone 2 from Australian hospitals. J Antimicrob Chemother 2011; 66: 1504-9.
4. Hamidian M, Hall RM. AbaR4 replaces AbaR3 in a carbapenemresistant Acinetobacter baumannii isolate belonging to global clone 1 from an Australian hospital. J Antimicrob Chemother 2011;66:2484-91.
5. Lambert T, Gerbaud G, Courvalin P. Transferable amikacin resistance in Acinetobacter spp. due to a new type of 3'-aminoglycoside phosphotransferase. Antimicrob Agents Chemother 1988; 32: 15-9.
6. Martin P, Jullien E, Courvalin P. Nucleotide sequence of Acinetobacter baumannii aphA-6 gene: evolutionary and functional implications of sequence homologies with nucleotide-binding proteins, kinases and other aminoglycoside-modifying enzymes. Mol Microbiol 1988; 2: 615-25.
7. Hamidian M, Holt KE, Pickard D et al. A GC1 Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid. J Antimicrob Chemother 2014; 69: 955-8.
8. Iacono M, Villa L, Fortini D et al. Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group. Antimicrob Agents Chemother 2008; 52: 2616-25.
9. Bertini A, Poirel L, Mugnier PD et al. Characterization and PCR-based replicon typing of resistance plasmids in Acinetobacter baumannii. Antimicrob Agents Chemother 2010; 54: 4168-77.