Fatigue is highly associated with poor health-related quality of life, disability and depression in newly-diagnosed patients with inflammatory bowel disease, independent of disease activity

Alimentary Pharmacology and Therapeutics

Volumn 39, Issue 8, 2014, Pages 811-822

  Cohen, B L ^a   Zoega H ^a,b   Shah, S A ^c   Leleiko, N ^c   Lidofsky, S ^c   Bright, R ^d   Flowers, N ^e   Law, M ^d   Moniz, H ^d   Merrick, M ^f   Sands, B E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ICELAND   (Iceland)

^c BROWN UNIVERSITY   (United States)

^d RHODE ISLAND HOSPITAL   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f Crohn's and Colitis Foundation of America   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; CROHN DISEASE; DEPRESSION; DISEASE ACTIVITY; DISEASE ASSOCIATION; EURO QUALITY OF LIFE INDEX; FATIGUE; FEMALE; FUNCTIONAL ASSESSMENT OF CHRONIC ILLNESS THERAPY FATIGUE SCALE; HUMAN; INFLAMMATORY BOWEL DISEASE QUESTIONNAIRE; MAJOR CLINICAL STUDY; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; PATIENT HEALTH QUESTIONNAIRE DEPRESSION SCALE; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; SHORT FORM 36; ULCERATIVE COLITIS; WORK DISABILITY; WORK PRODUCTIVITY AND ACTIVITY IMPAIRMENT QUESTIONNAIRE;

ADOLESCENT; ADULT; AGED; COHORT STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; DEPRESSION; DEPRESSIVE DISORDER; DISABILITY EVALUATION; FATIGUE; FEMALE; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PSYCHIATRIC STATUS RATING SCALES; QUALITY OF LIFE; QUESTIONNAIRES; REGISTRIES; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84896402257     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/apt.12659     Document Type: Article

References (58)

1. Molodecky NA, Soon IS, Rabi DM, et al,. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142: 46-54.e42.
2. Singh S, Blanchard A, Walker JR, Graff LA, Miller N, Bernstein CN,. Common symptoms and stressors among individuals with inflammatory bowel diseases. Clin Gastroenterol Hepatol 2011; 9: 769-75.
3. van Langenberg DR, Gibson PR,. Systematic review: fatigue in inflammatory bowel disease. Aliment Pharmacol Ther 2010; 32: 131-43.
4. Romberg-Camps MJL, Bol Y, Dagnelie PC, et al,. Fatigue and health-related quality of life in inflammatory bowel disease: results from a population-based study in the Netherlands: the IBD-South Limburg Cohort. Inflamm Bowel Dis 2010; 16: 2137-47.
5. Czuber-Dochan W, Ream E, Norton C,. Review article: description and management of fatigue in inflammatory bowel disease. Aliment Pharmacol Ther 2013; 37: 505-16.
6. Jelsness-Jorgensen LP, Bernklev T, Henriksen M, Torp R, Moum BA,. Chronic fatigue is associated with impaired health-related quality of life in inflammatory bowel disease. Aliment Pharmacol Ther 2011; 33: 106-14.
7. Bernklev T, Jahnsen J, Aadland E, et al,. Health-related quality of life in patients with inflammatory bowel disease five years after the initial diagnosis. Scand J Gastroenterol 2004; 39: 365-73.
8. Bernklev T, Jahnsen J, Lygren I, Henriksen M, Vatn M, Moum B,. Health-related quality of life in patients with inflammatory bowel disease measured with the short form-36: psychometric assessments and a comparison with general population norms. Inflamm Bowel Dis 2005; 11: 909-18.
9. Irvine EJ,. Quality of life issues in patients with inflammatory bowel disease. Am J Gastroenterol 1997; 92 (12 Suppl.): 18S-24S.
10. Jelsness-Jorgensen LP, Bernklev T, Henriksen M, Torp R, Moum B,. Chronic fatigue is associated with increased disease-related worries and concerns in inflammatory bowel disease. World J Gastroenterol 2012; 18: 445-52.
11. Simon GE, Von Korff M,. Medical co-morbidity and validity of DSM-IV depression criteria. Psychol Med 2006; 36: 27-36.
12. Wessely S,. Chronic fatigue: symptom and syndrome. Ann Intern Med 2001; 134: 838-43.
13. Williamson RJ, Purcell S, Sterne A, et al,. The relationship of fatigue to mental and physical health in a community sample. Soc Psychiatry Psychiatr Epidemiol 2005; 40: 126-32.
14. Swain MG,. Fatigue in chronic disease. Clin Sci (Lond) 2000; 99: 1-8.
15. Peyrin-Biroulet L,. What is the patient's perspective: how important are patient-reported outcomes, quality of life and disability Dig Dis 2010; 28: 463-71.
16. Tinsley A, Macklin EA, Korzenik JR, Sands BE,. Validation of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2011; 34: 1328-36.
17. Sands BE, LeLeiko N, Shah SA, Bright R, Grabert S,. OSCCAR: ocean state Crohn's and colitis area registry. Med Health R I 2009; 92: 82-5, 88.
18. Dassopoulos T, Nguyen GC, Bitton A, et al,. Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflamm Bowel Dis 2007; 13: 975-83.
19. The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Scale: Summary of development and validation. Available at: http://www.facit. org/Questionnaires. Accessed June 27, 2007.
20. Cella D, Lai JS, Chang CH, Peterman A, Slavin M,. Fatigue in cancer patients compared with fatigue in the general United States population. Cancer 2002; 94: 528-38.
21. Cella D, Yount S, Sorensen M, Chartash E, Sengupta N, Grober J,. Validation of the Functional Assessment of Chronic Illness Therapy Fatigue Scale relative to other instrumentation in patients with rheumatoid arthritis. J Rheumatol 2005; 32: 811-9.
22. Lai JS, Beaumont JL, Ogale S, Brunetta P, Cella D,. Validation of the functional assessment of chronic illness therapy-fatigue scale in patients with moderately to severely active systemic lupus erythematosus, participating in a clinical trial. J Rheumatol 2011; 38: 672-9.
23. Revicki DA, Rentz AM, Luo MP, Wong RL,. Psychometric characteristics of the short form 36 health survey and functional assessment of chronic illness Therapy-Fatigue subscale for patients with ankylosing spondylitis. Health Qual Life Outcomes 2011; 9: 36.
24. Signorovitch J, Brainsky A, Grotzinger KM,. Validation of the FACIT-fatigue subscale, selected items from FACT-thrombocytopenia, and the SF-36v2 in patients with chronic immune thrombocytopenia. Qual Life Res 2011; 20: 1737-44.
25. Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E,. Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. J Pain Symptom Manage 1997; 13: 63-74.
26. McHorney CA, Ware JE, Lu JF, Sherbourne CD,. The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care 1994; 32: 40-66.
27. Ware JE, Sherbourne CD,. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30: 473-83.
28. König HH, Ulshöfer A, Gregor M, et al,. Validation of the EuroQol questionnaire in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol 2002; 14: 1205-15.
29. Rabin R, de Charro F,. EQ-5D: a measure of health status from the EuroQol Group. Ann Med 2001; 33: 337-43.
30. Irvine EJ, Feagan B, Rochon J, et al,. Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group. Gastroenterology 1994; 106: 287-96.
31. Guyatt G, Mitchell A, Irvine EJ, et al,. A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology 1989; 96: 804-10.
32. Pallis AG, Vlachonikolis IG, Mouzas IA,. Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece. BMC Gastroenterol 2002; 2: 1.
33. Prasad M, Wahlqvist P, Shikiar R, Shih YC,. A review of self-report instruments measuring health-related work productivity: a patient-reported outcomes perspective. Pharmacoeconomics 2004; 22: 225-44.
34. Reilly MC, Gerlier L, Brabant Y, Brown M,. Validity, reliability, and responsiveness of the work productivity and activity impairment questionnaire in Crohn's disease. Clin Ther 2008; 30: 393-404.
35. Sandborn WJ, Reilly MC, Brown MCJ, Brabant Y, Gerlier LC,. Minimally important difference for WPAI: CD scores: defining relevant impact on work productivity in active Crohn's disease. Am J Gastroenterol 2007; 102: S472.
36. Kroenke K, Spitzer RL, Williams JB,. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001; 16: 606-13.
37. Kroenke K, Spitzer RL,. The PHQ-9: a new depression diagnostic and severity measure. Psychiatric Ann 2002; 32: 13.
38. Kroenke K, Strine TW, Spitzer RL, Williams JB, Berry JT, Mokdad AH,. The PHQ-8 as a measure of current depression in the general population. J Affect Disord 2009; 114: 163-73.
39. Cohen J,. A power primer. Psychol Bull 1992; 112: 155-9.
40. Thalheimer W, Cook S,. How to calculate effect sizes from published research articles: A simplified methodology, 2002. Available at: http://work-learning.com/effect-sizes.htm.
41. Harvey RF, Bradshaw JM,. A simple index of Crohn's-disease activity. Lancet 1980; 1: 514.
42. Walmsley RS, Ayres RC, Pounder RE, Allan RN,. A simple clinical colitis activity index. Gut 1998; 43: 29-32.
43. Gasche C, Berstad A, Befrits R, et al,. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases. Inflamm Bowel Dis 2007; 13: 1545-53.
44. Coteur G, Feagan B, Keininger DL, Kosinski M,. Evaluation of the meaningfulness of health-related quality of life improvements as assessed by the SF-36 and the EQ-5D VAS in patients with active Crohn's disease. Aliment Pharmacol Ther 2009; 29: 1032-41.
45. Nordin K, Påhlman L, Larsson K, Sundberg-Hjelm M, Lööf L,. Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease. Scand J Gastroenterol 2002; 37: 450-7.
46. Basu N, Jones GT, Fluck N, et al,. Fatigue: a principal contributor to impaired quality of life in ANCA-associated vasculitis. Rheumatology (Oxford) 2010; 49: 1383-90.
47. Huet PM, Deslauriers J, Tran A, Faucher C, Charbonneau J,. Impact of fatigue on the quality of life of patients with primary biliary cirrhosis. Am J Gastroenterol 2000; 95: 760-7.
48. Rupp I, Boshuizen HC, Jacobi CE, Dinant HJ, van den Bos GA,. Impact of fatigue on health-related quality of life in rheumatoid arthritis. Arthritis Rheum 2004; 51: 578-85.
49. Bager P, Befrits R, Wikman O, et al,. Fatigue in out-patients with inflammatory bowel disease is common and multifactorial. Aliment Pharmacol Ther 2012; 35: 133-41.
50. Graff LA, Vincent N, Walker JR, et al,. A population-based study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis 2011; 17: 1882-9.
51. Minderhoud IM, Oldenburg B, van Dam PS, Henegouwen GPV,. High prevalence of fatigue in quiescent inflammatory bowel disease is not related to adrenocortical insufficiency. Am J Gastroenterol 2003; 98: 1088-93.
52. Graff LA, Clara I, Lix LM, et al,. A longitudinal study of fatigue and disease activity in inflammatory bowel disease. Gastroenterology 2011; 140: S779.
53. Casellas F, Barreiro de Acosta M, Iglesias M, et al,. Mucosal healing restores normal health and quality of life in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol 2012; 24: 762-9.
54. Bernklev T, Jahnsen J, Henriksen M, et al,. Relationship between sick leave, unemployment, disability, and health-related quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis 2006; 12: 402-12.
55. Peyrin-Biroulet L, Cieza A, Sandborn WJ, et al,. Disability in inflammatory bowel diseases: developing ICF Core Sets for patients with inflammatory bowel diseases based on the International Classification of Functioning, Disability, and Health. Inflamm Bowel Dis 2010; 16: 15-22.
56. Peyrin-Biroulet L, Cieza A, Sandborn WJ, et al,. Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health. Gut 2012; 61: 241-7.
57. Lee TW, Iser JH, Sparrow MP, Newnham ED, Headon BJ, Gibson PR,. Thiopurines, a previously unrecognised cause for fatigue in patients with inflammatory bowel disease. J Crohns Colitis 2009; 3: 196-9.
58. Piche T, Ducrotté P, Sabate JM, et al,. Impact of functional bowel symptoms on quality of life and fatigue in quiescent Crohn disease and irritable bowel syndrome. Neurogastroenterol Motil 2010; 22: 626-e174.