Synthesis of thioether derivatives of quinazoline-4-one-2-thione and evaluation of their antiplatelet aggregation activity

Archives of Pharmacal Research

Volumn 37, Issue 3, 2014, Pages 332-339

  Eskandariyan, Zahra ^a   Esfahani Zadeh, Marjan ^a   Haj Mohammad Ebrahim Tehrani, Kamaleddin ^a   Mashayekhi, Vida ^a   Kobarfard, Farzad ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

2 (Arylmethylthio) 3 phenylquinazolin 4 one; Adenosine diphosphate; Antiplatelet aggregation; Arachidonic acid; Structure activity relationship; Thioether

Indexed keywords

2 ((PYRIDIN 3 YL)METHYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 ((PYRIDIN 4 YL)METHYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (2 CARBAMOYLBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (2 CHLOROBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (2 CYANOBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (2 METHYLBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (2 NITROBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (3 FLUOROBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (3 METHOXYBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (3 METHYLBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (4 METHYLBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (4 NITROBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (6 CHLORO 3,4 METHYLENEDIOXYBENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; 2 (BENZYLTHIO) 3 PHENYLQUINAZOLIN 4 ONE; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; QUINAZOLINE 4 ONE 2 THIONE; SULFIDE; UNCLASSIFIED DRUG; QUINAZOLINE DERIVATIVE; THIOKETONE;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; IC 50; NORMAL HUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY; THROMBOCYTE AGGREGATION; THROMBOCYTE RICH PLASMA; DRUG EFFECTS; PHYSIOLOGY; SYNTHESIS;

HUMANS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; QUINAZOLINES; SULFIDES; THIONES;

EID: 84896399891     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0192-5     Document Type: Article

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