In vitro studies on release and skin permeation of nonivamide from novel oil-in-oil-emulsions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 86, Issue 2, 2014, Pages 260-266

  Rottke, Michael ^a   Lunter, Dominique Jasmin ^a   Daniels, Rolf ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Nonivamide; Oil in oil emulsion; Permeation; Pig ear skin; Silicone oil; Topical delivery

Indexed keywords

CASTOR OIL; DIMETICONE; DRUG CARRIER; LIPID EMULSION; NONIVAMIDE; OIL IN OIL EMULSION; SILICONE; SURFACTANT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREAM; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; IN VITRO STUDY; NONHUMAN; SKIN PENETRATION; SWINE; VISCOSITY;

NONIVAMIDE; OIL-IN-OIL-EMULSION; PERMEATION; PIG EAR SKIN; SILICONE OIL; TOPICAL DELIVERY;

ANIMALS; CAPSAICIN; CASTOR OIL; DIMETHYLPOLYSILOXANES; EMULSIONS; OILS; PERMEABILITY; SILICONES; SKIN; SKIN ABSORPTION; SURFACE-ACTIVE AGENTS; SWINE;

EID: 84896399802     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.09.018     Document Type: Article

References (18)

1. M. Metz, and S. Ständer Chronic pruritus - pathogenesis, clinical aspects and treatment J. Eur. Acad. Dermatol. Venereol. 24 2010 1249 1260
2. D. Siepmann, C. Weishaupt, T.A. Luger, and S. Ständer Evaluation of the German guideline for chronic pruritus: results of a retrospective study on 385 patients Dermatology 223 2011 374 380
3. P. Anand, and K. Bley Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch Br. J. Anaesth. 107 2011 490 502
4. Bundesvereinigung Deutscher Apotheker, Hydrophile Capsaicinoid Creme 0.025%/0.05%/0.1% (NRF 11.125), Neues Rezeptur Formularium, D-Eschborn, 2010.
5. H. Kählig, A. Hasanovic, B. Biruss, S. Höller, J. Grimm, and C. Valenta Chitosan-glycolic acid: a possible matrix for progesterone delivery into skin Drug Dev. Ind. Pharm. 35 2009 997 1002
6. A.A. Attama, C. Weber, and C.C. Müller-Goymann Assessment of Drug Permeation from Lipid Nanoparticles formulated with a Novel Structured Lipid Matrix through Artificial Skin Construct Bio-engineered from HDF and HaCaT Cell Lines 2008 Editions de sant Paris, France
7. D.J. Lunter, and R. Daniels New film forming emulsions containing Eudragit® NE and/or RS 30D for sustained dermal delivery of nonivamide Eur. J. Pharm. Biopharm. 82 2012 291 298
8. D.J. Lunter, and R. Daniels In vitro skin permeation and penetration of nonivamide from novel film forming emulsions Skin Pharmacol. Physiol. 26 2012 139 146
9. V. Jaitely, T. Sakthivel, G. Magee, and A.T. Florence Formulation of Oil in Oil Emulsions: Potential Drug Reservoirs for Slow Release 2004 Editions de sant Paris, FRANCE
10. D. Floyd Silicone surfactants: applications in the personal care industry R.M. Hill, Silicone Surfactants 1999 Marcel Dekker Inc. New York 181 209
11. B. Grüning, and A. Bungard Silicone surfactants: emulsification R.M. Hill, Silicone Surfactants 1999 Marcel Dekker Inc. New York
12. M. Rottke, Entwicklung und Charakterisierung nonivamidhaltiger Rizinussöl-in-Silikonöl-Emulsionen zur dermalen Anwendung, 2012.
13. M.d.L. Reyes-Escogido, E.G. Gonzalez-Mondragon, and E. Vazquez-Tzompantzi Chemical and pharmacological aspects of capsaicin Molecules 16 2011 1253 1270
14. O. Suitthimeathegorn, V. Jaitely, and A.T. Florence Novel anhydrous emulsions: formulation as controlled release vehicles Int. J. Pharm. 298 2005 367 371 (Pubitemid 40910744)
15. A. Fick Ueber diffusion Ann. Phys. 170 1855 59 86
16. A. Einstein Über die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen Ann. Phys. 322 1905 549 560
17. J. Hadgraft Skin, the final frontier Int. J. Pharm. 224 2001 1 18 (Pubitemid 32706481)
18. T. Seki, M. Okamoto, O. Hosoya, D. Aiba, K. Morimoto, and K. Juni Effect of chondroitin sulfate on the diffusion coefficients of drugs in aqueous Solutions 13 2003 215 218 (Pubitemid 36903552)