Early trauma induced coagulopathy (ETIC): Prevalence across the injury spectrum

Injury

Volumn 45, Issue 5, 2014, Pages 910-915

  MacLeod, Jana B A ^a,b   Winkler, Anne M ^a   McCoy, Cameron C ^c   Hillyer, Christopher D ^d   Shaz, Beth H ^a,d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Karen Hospital   (Kenya)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NEW YORK BLOOD CENTER   (United States)

Author keywords

Coagulopathy; Mortality; Patient outcome; Prospective cohort; Resuscitation; Trauma

Indexed keywords

ADULT; ARTICLE; BLOOD CLOTTING DISORDER; COHORT ANALYSIS; CONTROLLED STUDY; CRYOPRECIPITATION; CRYSTALLOID; DAY HOSPITAL; EARLY TRAUMA INDUCED COAGULOPATHY; ERYTHROCYTE TRANSFUSION; FEMALE; HEAD INJURY; HUMAN; HYPOTENSION; INCIDENCE; INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PLASMA TRANSFUSION; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTHROMBIN TIME; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE COUNT; YOUNG ADULT; BLOOD COAGULATION DISORDERS; BLOOD TRANSFUSION; CLINICAL TRIAL; COMPLICATION; EARLY DIAGNOSIS; EMERGENCY HEALTH SERVICE; FLUID THERAPY; INJURY SCALE; MULTICENTER STUDY; PROCEDURES; RESUSCITATION; SURVIVAL; TREATMENT OUTCOME; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING;

ADULT; BLOOD COAGULATION DISORDERS; BLOOD TRANSFUSION; COHORT STUDIES; EARLY DIAGNOSIS; FEMALE; FLUID THERAPY; HOSPITAL MORTALITY; HUMANS; INJURY SEVERITY SCORE; MALE; PREVALENCE; PROSPECTIVE STUDIES; RESUSCITATION; SURVIVAL ANALYSIS; TRAUMA CENTERS; TREATMENT OUTCOME; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING;

EID: 84896394068     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2013.11.004     Document Type: Article

References (28)

1. Injury Prevention & Control: Data & Health Statistics (WISQARS™) Fatal injury data 2010 Available at: http://www.cdc.gov/injury/ wisqars/fatal.html [accessed 15.02.10]
2. R.L. Gruen, B.J. Gabbe, H.T. Stelfox, and P.A. Cameron Indicators of the quality of trauma care and the performance of trauma systems Br J Surg 99 Suppl. 1 2012 97 104
3. D.B. Hoyt, R. Coinberg, B. Potenza, J. Doucet, D. Fortlage, and P. Holingsworth-Fridlund et al. A twelve-year analysis of disease and provider complications on an organised Level I trauma service: as good as it gets? J Trauma Infect Crit Care 54 2003 26 37
4. A. Sauaia, F.A. Moore, E.E. Moore, K.S. Moser, R. Brennan, and R.A. Read et al. Epidemiology of trauma deaths: a reassessment J Trauma Infect Crit Care 38 2 1995 185 193
5. R.M. Stewart, J.G. Myers, D.L. Dent, P. Ermis, G.A. Gray, and R. Villarreal et al. Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention J Trauma Infect Crit Care 54 1 2003 66 70
6. S.R. Shackford, R.C. Mackersie, T.L. Holbrook, J.W. Davis, P. Hollingsworth-Fridlund, and D.B. Hoyt et al. The epidemiology of traumatic death. A population-based analysis Arch Surg 128 5 1993 571 575
7. C.C. Baker, L. Oppenheimer, B. Stephens, F.R. Lewis, and D.D. Trunkey Epidemiology of trauma deaths Am J Surg 140 1 1980 144 150
8. M.A. Borgman, P.C. Spinella, J.G. Perkins, K.W. Grathwohl, T. Repine, and A.C. Beekley et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital J Trauma Infect Crit Care 63 4 2007 805 813
9. J.B. Holcomb, C.E. Wade, J.E. Michalek, G.B. Chisholm, L.A. Zarzabal, and M.A. Schreiber et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients Ann Surg 248 3 2008 447 458
10. H.K. Stinger, P.C. Spinella, J.G. Perkins, K.W. Grathwohl, J. Salinas, and W.Z. Martini et al. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital J Trauma Infect Crit Care 64 2 Suppl. 2008 S79 S85
11. J.C. Duchesne, T.M. Islam, L. Stuke, J.R. Timmer, J.M. Barbeau, and A.B. Marr et al. Hemostatic resuscitation during surgery improves survival in patients with traumatic-induced coagulopathy J Trauma Infect Crit Care 67 1 2009 33 39
12. J.L. Sperry, J.B. Ochoa, S.R. Gunn, L.H. Alarcon, J.P. Minei, and J. Cuschieri et al. Inflammation the host response to injury investigators. An FFP:PRBC transfusion ratio ≥ 1:1.5 is associated with a lower risk of mortality after massive transfusion J Trauma Infect Crit Care 65 5 2008 986 993
13. N. Cosgriff, E.E. Moore, A. Sauaia, M. Kenny-Moynihan, J.M. Burch, and B. Galloway Predicting life-threatening coagulopathy in the massively transfused trauma patient: hypothermia and acidoses revisited J Trauma Infect Crit Care 42 5 1997 857 862
14. C.W. Schwab Introduction: damage control at the start of 21st century Injury 35 2004 639 641
15. F.A. Moore, B.A. McKinley, and E.E. Moore The next generation in shock resuscitation Lancet 363 9425 2004 1988 1996
16. J.B. Holcomb, D. Jenkins, P. Rhee, J. Johannigman, P. Mahoney, and S. Mehta et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma J Trauma Infect Crit Care 62 2 2007 307 310
17. J.B. MacLeod, M. Lynn, M. McKenney, S.M. Cohn, and M. Murtha Early coagulopathy predicts mortality in trauma J Trauma Infect Crit Care 55 1 2003 39 44
18. K. Brohi, J. Singh, M. Heron, and T. Coats Acute traumatic coagulopathy J Trauma Infect Crit Care 54 2003 1127 1130
19. D. Rixen, M. Raum, B. Bouillon, L.E. Schlosser, and E. Neugebauer Predicting the outcome in severe injuries: an analysis of 2069 patients from the Trauma Register of the German Society of Traumatology (DGU) Unfallchirurg 104 3 2001 230 239
20. J.R. Hess, A.L. Lindell, L.G. Stansbury, R.P. Dutton, and T.M. Scalea The prevalence of abnormal results of conventional coagulation tests on admission to a trauma center Transfusion 49 1 2009 34 39
21. B.H. Shaz, C.J. Dente, R.S. Harris, J.B. MacLeod, and C.D. Hillyer Transfusion management of trauma patients Anesth Analg 108 2009 1760 1768
22. B.H. Shaz, A.M. Winkler, A.B. James, C.D. Hillyer, and J.B. Macleod Pathophysiology of early trauma induced coagulopathy (ETIC): emerging evidence for hemodilution and coagulation factor depletion J Trauma Infect Crit Care 70 6 2011 1401 1407
23. V.A. Eddy, J.A. Morris Jr., and D.C. Cullinane Hypothermia, coagulopathy and acidosis Surg Clin North America 80 June (3) 2000 845 854
24. B. Mitra, F. Tullio, P.A. Cameron, and M. Fitzgerald Trauma patients with the triad of death Emerg Med J 29 August (8) 2012 622 625
25. J.R. Hess, K. Brohi, R.P. Dutton, C.J. Hauser, J.B. Holcomb, and Y. Kluger et al. The coagulopathy of trauma: a review of mechanisms J Trauma Infect Crit Care 65 4 2008 748 754
26. J.B. MacLeod Trauma and coagulopathy: a new paradigm to consider Arch Surg 143 8 2008 797 801
27. K. Brohi, M.J. Cohen, M.T. Ganter, M.A. Matthay, R.C. Mackersie, and J.F. Pittet Acute traumatic coagulopathy: initiaed by hypoperfusion modulated through the protein C pathway? Ann Surg 245 2007 812 818
28. I.J. Welsby, M.V. Podgoreanu, B. Phillips-Bute, J.P. Mathew, P.K. Smith, and M.F. Newman et al. Perioperative genetics and safety outcomes study (PEGASUS) investigative team. Genetic factors contribute to bleeding after cardiac surgery J Thromb Haemost 3 6 2005 1206 1212