Is there a role for postoperative treatment in patients with stage Ib 2-IIb cervical cancer treated with neo-adjuvant chemotherapy and radical surgery? An Italian multicenter retrospective study

Gynecologic Oncology

Volumn 132, Issue 3, 2014, Pages 611-617

  Landoni, F ^a   Sartori, E ^b   Maggino, T ^c   Zola, P ^d   Zanagnolo, V ^a   Cosio, S ^e   Ferrari, F ^b   Piovano, E ^d   Gadducci, A ^e  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c Umberto I Hospital   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

^e UNIVERSITY OF PISA   (Italy)

Author keywords

Adjuvant treatment; Cervical cancer; Chemotherapy; Survival

Indexed keywords

ANTINEOPLASTIC AGENT; PLATINUM DERIVATIVE;

ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONSOLIDATION CHEMOTHERAPY; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MIDDLE AGED; OUTCOME ASSESSMENT; OVERALL SURVIVAL; POSTOPERATIVE CARE; PRIORITY JOURNAL; RADICAL HYSTERECTOMY; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; UTERINE CERVIX CANCER;

ADJUVANT TREATMENT; CERVICAL CANCER; CHEMOTHERAPY; SURVIVAL;

ADENOCARCINOMA; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRACHYTHERAPY; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; CHEMOTHERAPY, ADJUVANT; CISPLATIN; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; HYSTERECTOMY; LYMPH NODE EXCISION; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; POSTOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; RETROSPECTIVE STUDIES; UTERINE CERVICAL NEOPLASMS;

EID: 84896388113     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2013.12.010     Document Type: Article

References (18)

1. L.A. Rojas-Espaillat, and P.G. Rose Management of locally advanced cervical cancer Curr Opin Oncol 17 2005 485 492
2. Chemoradiotherapy for Cervical Cancer Meta-analysis Collaboration (CCCMAC) Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: individual patient data meta-analysis Cochrane Database Syst Rev 20 2010 CD008285
3. C. Vale, J.F. Tierney, L. Stewart Chemotherapy for cervical cancer meta-analysis collaboration Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials J Clin Oncol 26 2008 5802 5812
4. A. Dueñas-González, J.J. Zarbá, F. Patel, J.C. Alcedo, S. Beslija, and L. Casanova et al. Phase III, open-label, randomized study comparing concurrent gemcitabine plus cisplatin and radiation followed by adjuvant gemcitabine and cisplatin versus concurrent cisplatin and radiation in patients with stage IIB to IVA carcinoma of the cervix J Clin Oncol 29 2011 1678 1685
5. A. Abe, H. Furumoto, M. Nishimura, M. Irahara, and H. Ikushima Adjuvant chemotherapy following concurrent chemoradiotherapy for uterine cervical cancer with lymphadenopathy Oncol Lett 3 2012 571 576
6. P. Morice, P. Rouanet, A. Rey, P. Romestaing, G. Houvenaeghel, and J.C. Boulanger et al. Results of the GYNECO 02 study, an FNCLCC phase III trial comparing hysterectomy with no hysterectomy in patients with a (clinical and radiological) complete response after chemoradiation therapy for stage IB2 or II cervical cancer Oncologist 17 2012 64 71
7. P.B. Panici, G. Scambia, G. Baiocchi, S. Greggi, G. Ragusa, and A. Gallo et al. Neoadjuvant chemotherapy and radical surgery in locally advanced cervical cancer. Prognostic factors for response and survival Cancer 67 1991 372 379
8. J.E. Sardi, A. Giaroli, C. Sananes, M. Ferreira, A. Soderini, and A. Bermudez et al. Long-term follow-up of the first randomized trial using neoadjuvant chemotherapy in stage Ib squamous carcinoma of the cervix: the final results Gynecol Oncol 67 1997 61 69
9. P. Benedetti-Panici, S. Greggi, A. Colombo, M. Amoroso, D. Smaniotto, and D. Giannarelli et al. Neoadjuvant chemotherapy and radical surgery versus exclusive radiotherapy in locally advanced squamous cell cervical cancer: results from the Italian multicenter randomized study J Clin Oncol 20 2002 179 188
10. Neoadjuvant Chemotherapy for Cervical Cancer Meta-Analysis Collaboration (NACCCMA) Neoadjuvant chemotherapy for locally advanced cervix cancer Cochrane Database Syst Rev 2 2004 CD001774
11. A. Buda, R. Fossati, N. Colombo, F. Fei, I. Floriani, and D. Gueli Alletti et al. Randomized trial of neoadjuvant chemotherapy comparing paclitaxel, ifosfamide, and cisplatin with ifosfamide and cisplatin followed by radical surgery in patients with locally advanced squamous cell cervical carcinoma: the SNAP01 (Studio Neo-AdjuvantePortio) Italian Collaborative Study J Clin Oncol 23 2005 4137 4145
12. A. González-Martín, L. González-Cortijo, N. Carballo, J.F. Garcia, F. Lapuente, and A. Rojo et al. The current role of neoadjuvant chemotherapy in the management of cervical carcinoma Gynecol Oncol 110 3 Suppl 2 2008 S36 S40
13. A.A. Lissoni, N. Colombo, A. Pellegrino, G. Parma, P. Zola, and D. Katsaros et al. A phase II, randomized trial of neo-adjuvant chemotherapy comparing a three-drug combination of paclitaxel, ifosfamide, and cisplatin (TIP) versus paclitaxel and cisplatin (TP) followed by radical surgery in patients with locally advanced squamous cell cervical carcinoma: the Snap-02 Italian Collaborative Study Ann Oncol 20 2009 660 665
14. Y.H. Cho, D.Y. Kim, J.H. Kim, Y.M. Kim, Y.T. Kim, and J.H. Nam Comparative study of neoadjuvant chemotherapy before radical hysterectomy and radical surgery alone in stage IB2-IIA bulky cervical cancer J Gynecol Oncol 20 2009 22 27
15. Y.H. Cho, D.Y. Kim, J.H. Kim, Y.M. Kim, Y.T. Kim, and J.H. Nam Two-year survival: preoperative adjuvant chemotherapy in the treatment of cervical cancer stages Ib and II with bulky tumor Gyneco Oncol 33 1989 225 230
16. A. Giaroli, C. Sananes, J.E. Sardi, A.G. Maya, M.L. Bastardas, and L. Snaidas et al. Lymph node metastases in carcinoma of the cervix uteri: response to neoadjuvant chemotherapy and its impact on survival Gynecol Oncol 39 1990 34 39
17. N. Colombo, A. Gabriele, and A. Lissoni Neoadjuvant chemotherapy (NACT) in locally advanced uterine cervical cancer (LAUCC): correlation between pathological response and survival Proc Am Soc Clin Oncol 17 1998 352a [abstr 1359]
18. K.S. Tewari, M. Sill, and H.L. Long Incorporation of bevacizumab in the treatment of recurrent and metastatic cervical cancer: a phase III randomized trial of the Gynecologic Oncology Group J Clin Oncol 31 2013 [Suppl.; abstr 3]