Proteomic analysis of plasma-purified VLDL, LDL, and HDL fractions from atherosclerotic patients undergoing carotid endarterectomy: Identification of serum amyloid a as a potential marker

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2013, Pages

  Lepedda, Antonio J ^a   Nieddu, Gabriele ^a   Zinellu, Elisabetta ^a   De Muro, Pierina ^a   Piredda, Franco ^a   Guarino, Anna ^b   Spirito, Rita ^b   Carta, Franco ^c   Turrini, Francesco ^d   Formato, Marilena ^a  

^a UNIVERSITY OF SASSARI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Nurex Srl   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; ELECTROPHORESIS; GLYCOPROTEINS; MASS SPECTROMETRY; PLASMAS;

CAROTID ENDARTERECTOMIES; COMPREHENSIVE METHOD; LIPOPROTEIN FRACTION; MASS SPECTROMETRY ANALYSIS; PEPTIDE MASS FINGERPRINTING; STRUCTURAL STABILIZATION; THERAPEUTIC STRATEGY; TWO-DIMENSIONAL ELECTROPHORESIS (2-DE);

LIPOPROTEINS;

APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; APOLIPOPROTEIN B100; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN D; APOLIPOPROTEIN E; CLUSTERIN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SERUM AMYLOID A; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN; APOLIPOPROTEIN; BIOLOGICAL MARKER;

ARTICLE; ATHEROGENESIS; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; FEMALE; HUMAN; HYDROPHOBICITY; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PLASMA; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEOMICS; TWO DIMENSIONAL ELECTROPHORESIS; WESTERN BLOTTING; ATHEROSCLEROSIS; BLOOD; CASE CONTROL STUDY; CELL FRACTIONATION; CHEMISTRY; METABOLISM; METHODOLOGY;

APOLIPOPROTEINS; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; ENDARTERECTOMY, CAROTID; FEMALE; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MALE; PROTEOMICS; SERUM AMYLOID A PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBCELLULAR FRACTIONS;

EID: 84896354136     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/385214     Document Type: Article

References (53)

1. Lutgens E., van Suylen R.-J., Faber B. C., Gijbels M. J., Eurlings P. M., Bijnens A.-P., Cleutjens K. B., Heeneman S., Daemen M. J. A. P., Atherosclerotic plaque rupture: local or systemic process? Arteriosclerosis, Thrombosis, and Vascular Biology 2003 23 12 2123 2130 2-s2.0-0346753453 10.1161/01.ATV.0000097783.01596.E2 (Pubitemid 37532310)
2. Libby P., Inflammation in atherosclerosis. Nature 2002 420 6917 868 874 2-s2.0-0037180771 10.1038/nature01323 (Pubitemid 36019640)
3. Williams K. J., Tabas I., The response-to-retention hypothesis of early atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology 1995 15 5 551 562 2-s2.0-0029299438
4. Skålén K., Gustafsson M., Knutsen Rydberg E., Hultén L. M., Wiklund O., Innerarity T. L., Boren J., Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature 2002 417 6890 750 754 2-s2.0-0037071843 10.1038/nature00804 (Pubitemid 34640629)
5. Jonas A., Phillips M. C., Vance D. E., Vance J. E., Lipoprotein structure. Biochemistry of Lipids, Lipoprotein and Membranes 2008 5th Elsevier 485 506
6. Bolanos-Garcia V. M., Miguel R. N., On the structure and function of apolipoproteins: more than a family of lipid-binding proteins. Progress in Biophysics and Molecular Biology 2003 83 1 47 68 2-s2.0-0038737056 10.1016/S0079-6107(03)00028-2 (Pubitemid 36572978)
7. Walldius G., Jungner I., Holme I., Aastveit A. H., Kolar W., Steiner E., High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. The Lancet 2001 358 9298 2026 2033 2-s2.0-0035894648 10.1016/S0140-6736(01)07098-2 (Pubitemid 34084825)
8. Lepedda A. J., Zinellu E., Formato M., Man T.-K., Flores J. R., Overview of current proteomic approaches for discovery of vascular biomarkers of atherosclerosis. Proteomics-Human Diseases and Protein Functions 2012 InTech 3 32
9. von Zychlinski A., Kleffmann T., Williams M. J. A., McCormick S. P., Proteomics of Lipoprotein(a) identifies a protein complement associated with response to wounding. Journal of Proteomics 2011 74 12 2881 2891 2-s2.0-81055156223 10.1016/j.jprot.2011.07.008
10. Vaisar T., Pennathur S., Green P. S., Gharib S. A., Hoofnagle A. N., Cheung M. C., Byun J., Vuletic S., Kassim S., Singh P., Chea H., Knopp R. H., Brunzell J., Geary R., Chait A., Zhao X.-Q., Elkon K., Marcovina S., Ridker P., Oram J. F., Heinecke J. W., Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. Journal of Clinical Investigation 2007 117 3 746 756 2-s2.0-33847368173 10.1172/JCI26206 (Pubitemid 46348533)
11. Green P. S., Vaisar T., Pennathur S., Kulstad J. J., Moore A. B., Marcovina S., Brunzell J., Knopp R. H., Zhao X.-Q., Heinecke J. W., Combined statin and niacin therapy remodels the high-density lipoprotein proteome. Circulation 2008 118 12 1259 1267 2-s2.0-53449083547 10.1161/CIRCULATIONAHA.108. 770669
12. Vaisar T., Mayer P., Nilsson E., Zhao X.-Q., Knopp R., Prazen B. J., HDL in humans with cardiovascular disease exhibits a proteomic signature. Clinica Chimica Acta 2010 411 13-14 972 979 2-s2.0-77952543789 10.1016/j.cca.2010.03.023
13. Alwaili K., Bailey D., Awan Z., Bailey S. D., Ruel I., Hafiane A., Krimbou L., Laboissiere S., Genest J., The HDL proteome in acute coronary syndromes shifts to an inflammatory profile. Biochimica et Biophysica Acta 2012 1821 3 405 415 2-s2.0-84857637772 10.1016/j.bbalip.2011.07.013
14. Cubedo J., Padró T., Alonso R., Cinca J., Mata P., Badimon L., Differential proteomic distribution of TTR (pre-albumin) forms in serum and HDL of patients with high cardiovascular risk. Atherosclerosis 2012 222 1 263 269 2-s2.0-84859831988 10.1016/j.atherosclerosis.2012.02.024
15. Heller M., Schlappritzi E., Stalder D., Nuoffer J.-M., Haeberli A., Compositional protein analysis of high density lipoproteins in hypercholesterolemia by shotgun LC-MS/MS and probabilistic peptide scoring. Molecular and Cellular Proteomics 2007 6 6 1059 1072 2-s2.0-34347377132 10.1074/mcp.M600326-MCP200 (Pubitemid 47019407)
16. Mazura M. T., Cardasis H. L., Spellman D. S., Liaw A., Yates N. A., Hendrickson R. C., Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 2010 107 17 7728 7733 2-s2.0-77952366352 10.1073/pnas.0910776107
17. Levels J. H. M., Geurts P., Karlsson H., Marée R., Ljunggren S., Fornander L., Wehenkel L., Lindahl M., Stroes E. S. G., Kuivenhoven J. A., Meijers J. C. M., High-density lipoprotein proteome dynamics in human endotoxemia. Proteome Science 2011 9, article 34 2-s2.0-79959608513 10.1186/1477-5956-9-34
18. Davidsson P., Hulthe J., Fagerberg B., Olsson B.-M., Hallberg C., Dahllö B., Camejo G., A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes. Journal of Lipid Research 2005 46 9 1999 2006 2-s2.0-24344495315 10.1194/jlr.M500161- JLR200 (Pubitemid 41248497)
19. Bondarenko P. V., Cockrill S. L., Watkins L. K., Cruzado I. D., Macfarlane R. D., Mass spectral study of polymorphism of the apolipoproteins of very low density lipoprotein. Journal of Lipid Research 1999 40 3 543 555 2-s2.0-0033014724 (Pubitemid 29116158)
20. Lepedda A. J., Cigliano A., Cherchi G. M., Spirito R., Maggioni M., Carta F., Turrini F., Edelstein C., Scanu A. M., Formato M., A proteomic approach to differentiate histologically classified stable and unstable plaques from human carotid arteries. Atherosclerosis 2009 203 1 112 118 2-s2.0-60949088459 10.1016/j.atherosclerosis.2008.07.001
21. Lepedda A. J., Zinellu A., Nieddu G., Zinellu E., Carru C., Spirito R., Guarino A., de Muro P., Formato M., Protein sulfhydryl group oxidation and mixed-disulfide modifications in stable and unstable human carotid plaques. Oxidative Medicine and Cellular Longevity 2013 2013 8 403973 10.1155/2013/403973
22. Himber J., Buhler E., Moll D., Moser U. K., Low density lipoprotein for oxidation and metabolic studies. Isolation from small volumes of plasma using a tabletop ultracentrifuge. International Journal for Vitamin and Nutrition Research 1995 65 2 137 142 2-s2.0-0028831588
23. McDowell I. F. W., McEneny J., Trimble E. R., A rapid method for measurement of the susceptibility to oxidation of low-density lipoprotein. Annals of Clinical Biochemistry 1995 32 2 167 174 2-s2.0-0028913598
24. Mastro R., Hall M., Protein delipidation and precipitation by tri-n-butylphosphate, acetone, and methanol treatment for isoelectric focusing and two-dimensional gel electrophoresis. Analytical Biochemistry 1999 273 2 313 315 2-s2.0-0033543717 10.1006/abio.1999.4224 (Pubitemid 29430678)
25. King V. L., Thompson J., Tannock L. R., Serum amyloid A in atherosclerosis. Current Opinion in Lipidology 2011 22 4 302 307 2-s2.0-79960648848 10.1097/MOL.0b013e3283488c39
26. Tam S. P., Flexman A., Hulme J., Kisilevsky R., Promoting export of macrophage cholesterol: the physiological role of a major acute-phase protein, serum amyloid A 2.1. Journal of Lipid Research 2002 43 9 1410 1420 2-s2.0-0036737704 10.1194/jlr.M100388-JLR200
27. Stonik J. A., Remaley A. T., Demosky S. J., Neufeld E. B., Bocharov A., Brewer H. B., Serum Amyloid a promotes ABCA1-dependent and ABCA1-independent lipid efflux from cells. Biochemical and Biophysical Research Communications 2004 321 4 936 941 2-s2.0-3843107923 10.1016/j.bbrc.2004.07.052 (Pubitemid 39044399)
28. -/- mice. Journal of Lipid Research 2005 46 10 2091 2101 2-s2.0-25444442411 10.1194/jlr.M500191-JLR200 (Pubitemid 41377461)
29. van der Westhuyzen D. R., Cai L., DeBeer M. C., DeBeer F. C., Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I. Journal of Biological Chemistry 2005 280 43 35890 35895 2-s2.0-27744512551 10.1074/jbc.M505685200 (Pubitemid 41633856)
30. Kisilevsky R., Tam S. P., Ancsin J. B., The anti-atherogenic potential of serum amyloid A peptides. Current Opinion in Investigational Drugs 2008 9 3 265 273 2-s2.0-40049094021 (Pubitemid 351323379)
31. Badolato R., Wang J. M., Murphy W. J., Lloyd A. R., Michiel D. F., Bausserman L. L., Kelvin D. J., Oppenheim J. J., Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. Journal of Experimental Medicine 1994 180 1 203 209 2-s2.0-23444460848 10.1084/jem.180.1.203 (Pubitemid 24181069)
32. Ha Y. L., Sang D. K., Jae W. S., Sun Y. L., Lee H., Cho K.-H., Yun J., Bae Y.-S., Serum amyloid A induces CCL2 production via formyl peptide receptor-like 1-mediated signaling in human monocytes. Journal of Immunology 2008 181 6 4332 4339 2-s2.0-56149092965
33. Dong Z., Wu T., Qin W., An C., Wang Z., Zhang M., Zhang Y., Zhang C., An F., Serum amyloid a directly accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Molecular Medicine 2011 17 11 1357 1364 2-s2.0-82855164033 10.2119/molmed.2011.00186
34. Lee H. Y., Kim S. D., Baek S. H., Choi J. H., Cho K. H., Zabel B. A., Bae Y. S., Serum amyloid A stimulates macrophage foam cell formation via lectin-like oxidized low-density lipoprotein receptor 1 upregulation. Biochemical and Biophysical Research Communications 2013 433 1 18 23 10.1016/j.bbrc.2013.02.077
35. Furlaneto C. J., Campa A., A novel function of serum amyloid A: a potent stimulus for the release of tumor necrosis factor-interleukin-1 β and interleukin-8 by human blood neutrophil. Biochemical and Biophysical Research Communications 2000 268 2 405 408 2-s2.0-0034673318 10.1006/bbrc.2000.2143 (Pubitemid 30119635)
36. Song C., Hsu K., Yamen E., Yan W., Fock J., Witting P. K., Geczy C. L., Freedman S. B., Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytes. Atherosclerosis 2009 207 2 374 383 2-s2.0-70450278985 10.1016/j.atherosclerosis.2009.05.007
37. Hua S., Song C., Geczy C. L., Freedman S. B., Witting P. K., A role for acute-phase serum amyloid A and high-density lipoprotein in oxidative stress, endothelial dysfunction and atherosclerosis. Redox Report 2009 14 5 187 196 2-s2.0-73649135358 10.1179/135100009X12525712409490
38. Witting P. K., Song C., Hsu K., Hua S., Parry S. N., Aran R., Geczy C., Freedman S. B., The acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoprotein. Free Radical Biology and Medicine 2011 51 7 1390 1398 2-s2.0-80052265183 10.1016/j.freeradbiomed. 2011.06.031
39. Song C., Shen Y., Yamen E., Hsu K., Yan W., Witting P. K., Geczy C. L., Freedman S. B., Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes. Atherosclerosis 2009 202 2 596 604 2-s2.0-63849227423 10.1016/j.atherosclerosis.2008.04.049
40. Wilson P. G., Thompson J. C., Webb N. R., DeBeer F. C., King V. L., Tannock L. R., Serum amyloid A, but not C-reactive protein, stimulates vascular proteoglycan synthesis in a pro-atherogenic manner. American Journal of Pathology 2008 173 6 1902 1910 2-s2.0-57149097662 10.2353/ajpath.2008.080201
41. Ancsin J. B., Kisilevsky R., Serum amyloid A peptide interactions with glycosaminoglycans. Evaluation by affinity chromatography. Methods in Molecular Biology 2001 171 449 456 2-s2.0-0035231332
42. O'Brien K. D., McDonald T. O., Kunjathoor V., Eng K., Knopp E. A., Lewis K., Lopez R., Kirk E. A., Chait A., Wight T. N., DeBeer F. C., LeBoeuf R. C., Serum amyloid A and lipoprotein retention in murine models of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 4 785 790 2-s2.0-20144387658 10.1161/01.ATV.0000158383.65277.2b (Pubitemid 40463870)
43. Yamada T., Kakihara T., Kamishima T., Fukuda T., Kawai T., Both acute phase and constitutive serum amyloid A are present in atherosclerotic lesions. Pathology International 1996 46 10 797 800 2-s2.0-0029834741 (Pubitemid 26353233)
44. Meek R. L., Urieli-Shoval S., Benditt E. P., Expression of apolipoprotein serum amyloid A mRNA in human atherosclerotic lesions and cultured vascular cells: implications for serum amyloid A function. Proceedings of the National Academy of Sciences of the United States of America 1994 91 8 3186 3190 2-s2.0-0028202075 (Pubitemid 24130200)
45. Liuzzo G., Biasucci L. M., Gallimore J. R., Grillo R. L., Rebuzzi A. G., Pepys M. B., Maseri A., The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. The New England Journal of Medicine 1994 331 7 417 424 2-s2.0-0027933081 10.1056/NEJM199408183310701 (Pubitemid 24247397)
46. Fyfe A. I., Rothenberg L. S., DeBeer F. C., Cantor R. M., Rotter J. I., Lusis A. J., Association between serum amyloid A proteins and coronary artery disease: evidence from two distinct arteriosclerotic processes. Circulation 1997 96 9 2914 2919 2-s2.0-0030685738 (Pubitemid 27500090)
47. Erren M., Reinecke H., Junker R., Fobker M., Schulte H., Schurek J. O., Kropf J., Kerber S., Breithardt G., Assmann G., Cullen P., Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries. Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 10 2355 2363 2-s2.0-0032849727 (Pubitemid 29477836)
48. Rifai N., Joubran R., Yu H., Asmi M., Jouma M., Inflammatory markers in men with angiographically documented coronary heart disease. Clinical Chemistry 1999 45 11 1967 1973 2-s2.0-0032754882 (Pubitemid 29522005)
49. Jousilahti P., Salomaa V., Rasi V., Vahtera E., Palosuo T., The association of c-reactive protein, serum amyloid a and fibrinogen with prevalent coronary heart disease-baseline findings of the PAIS project. Atherosclerosis 2001 156 2 451 456 2-s2.0-0035015446 10.1016/S0021-9150(00)00681-X (Pubitemid 32522927)
50. Delanghe J. R., Langlois M. R., de Bacquer D., Mak R., Capel P., van Renterghem L., de Backer G., Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002 160 2 471 476 2-s2.0-0036182631 10.1016/S0021-9150(01)00607-4 (Pubitemid 34159343)
51. Ogasawara K., Mashiba S., Wada Y., Sahara M., Uchida K., Aizawa T., Kodama T., A serum amyloid A and LDL complex as a new prognostic marker in stable coronary artery disease. Atherosclerosis 2004 174 2 349 356 2-s2.0-2342580664 10.1016/j.atherosclerosis.2004.01.030 (Pubitemid 38597093)
52. Johnson B. D., Kip K. E., Marroquin O. C., Ridker P. M., Kelsey S. F., Shaw L. J., Pepine C. J., Sharaf B., Bairey Merz C. N., Sopko G., Olson M. B., Reis S. E., Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: The National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation 2004 109 6 726 732 2-s2.0-10744226950 10.1161/01.CIR.0000115516.54550.B1 (Pubitemid 38222891)
53. Lee K. W. J., Hill J. S., Walley K. R., Frohlich J. J., Relative value of multiple plasma biomarkers as risk factors for coronary artery disease and death in an angiography cohort. Canadian Medical Association Journal 2006 174 4 461 466 2-s2.0-33644539192 10.1503/cmaj.050880