CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7307-7319

  Calco, Gina N ^a   Stephens, Olivia R ^a   Donahue, Laura M ^a   Tsui, Cynthia C ^b   Pierchala, Brian A ^b  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; DEGRADATION; PROTEINS;

CD2-ASSOCIATED PROTEINS; COILED-COIL DOMAINS; DEGRADATION KINETICS; DEGRADATION PROCESS; DIFFERENT MECHANISMS; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; RECEPTOR TYROSINE KINASE; SRC HOMOLOGY 3 DOMAINS;

NEURONS;

CBL 3 PROTEIN; CBL PROTEIN; CD2 ASSOCIATED PROTEIN; ISOPROTEIN; LYSINE; PROTEIN RET; PROTEIN SH3; RING FINGER PROTEIN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; MAMMAL CELL; MOLECULAR MECHANICS; NERVE CELL; NERVE FIBER GROWTH; PODOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION;

NEURODEVELOPMENT; NEUROTROPHIC FACTOR; PROTEIN DEGRADATION; RECEPTOR TYROSINE KINASE; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOSKELETAL PROTEINS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; LYSINE; MICE; MUTATION; NIH 3T3 CELLS; PHOSPHORYLATION; PODOCYTES; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-CBL; PROTO-ONCOGENE PROTEINS C-RET; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; UBIQUITIN; UBIQUITINATION;

EID: 84896303355     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.537878     Document Type: Article

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