Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

Development (Cambridge)

Volumn 141, Issue 7, 2014, Pages 1465-1472

  Lee, Monica Y ^a   Skoura, Athanasia ^a   Park, Eon Joo ^a   Landskroner Eiger, Shira ^a   Jozsef, Levente ^a   Luciano, Amelia K ^a   Murata, Takahisa ^b   Pasula, Satish ^c   Dong, Yunzhou ^c   Bouaouina, Mohamed ^a   Calderwood, David A ^a   Ferguson, Shawn M ^c   De Camilli, Pietro ^a   Sessa, William C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Angiogenesis; Endocytosis; Endothelium; Mouse

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; ALPHAVBETA5 INTEGRIN; BETA1 INTEGRIN; CLATHRIN; CLATHRIN HEAVY CHAIN; DYNAMIN II; EPIDERMAL GROWTH FACTOR RECEPTOR; F ACTIN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; PAXILLIN; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE B; SMALL INTERFERING RNA; TAMOXIFEN; TRANSFERRIN; VASCULOTROPIN; VASCULOTROPIN 165; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRANCHING MORPHOGENESIS; CALCIUM CELL LEVEL; CELL CULTURE; CELL MIGRATION; CELL MOTILITY; CELL SURFACE; CELL VIABILITY; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENDOCYTOSIS; ENDOTHELIUM CELL; ENZYME REGULATION; FIBROBLAST; FLUORESCENCE ACTIVATED CELL SORTING; FOCAL ADHESION; GENE EXPRESSION; GENE INACTIVATION; GENE SILENCING; HUGO GENE NOMENCLATURE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MOUSE; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RETINA BLOOD VESSEL; SIGNAL TRANSDUCTION; STRESS FIBER; TURNOVER TIME; YOLK SAC;

ANGIOGENESIS; ENDOCYTOSIS; ENDOTHELIUM; MOUSE;

ANIMALS; ANIMALS, NEWBORN; BLOOD VESSELS; CELLS, CULTURED; DYNAMIN II; EMBRYO, MAMMALIAN; ENDOCYTOSIS; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTEGRINS; MALE; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84896295981     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.104539     Document Type: Article

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