Signal peptide cleavage from GP3 enabled by removal of adjacent glycosylation sites does not impair replication of equine arteritis virus in cell culture, but the hydrophobic C-terminus is essential

Virus Research

Volumn 183, Issue , 2014, Pages 107-111

  Matczuk, Anna Karolina ^a   Veit, Michael ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Arterivirus; Equine arteritis virus; Glycosylation; GP3; Membrane topology; Signal peptide

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN GP 3; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CONTROLLED STUDY; EQUINE VIRAL ARTERITIS VIRUS; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS PARTICLE; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE;

ARTERIVIRUS; EQUINE ARTERITIS VIRUS; GLYCOSYLATION; GP3; MEMBRANE TOPOLOGY; SIGNAL PEPTIDE;

ANIMALS; ARTERITIS VIRUS, EQUINE; CELL LINE; CRICETINAE; GLYCOSYLATION; MODELS, BIOLOGICAL; PROTEIN SORTING SIGNALS; PROTEOLYSIS; VIRAL ENVELOPE PROTEINS; VIRAL LOAD; VIRAL PLAQUE ASSAY; VIRUS REPLICATION;

EID: 84896285961     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.02.005     Document Type: Article

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