High altitude exposure alters gene expression levels of DNA repair enzymes, and modulates fatty acid metabolism by SIRT4 induction in human skeletal muscle

Respiratory Physiology and Neurobiology

Volumn 196, Issue 1, 2014, Pages 33-37

  Acs, Zoltan ^a   Bori, Zoltan ^a   Takeda, Masaki ^a   Osvath, Peter ^a   Berkes, Istvan ^a   Taylor, Albert W ^b   Yang, Hu ^c   Radak, Zsolt ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c BEIJING SPORT UNIVERSITY   (China)

Author keywords

DNA damage; High altitude; Oxidative stress; Sirtuins

Indexed keywords

8 HYDROXYGUANINE; BETA ACTIN; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOPEPTIDASE LA; KU ANTIGEN; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SIRTUIN 1; SIRTUIN 3; SIRTUIN 4; SIRTUIN 6; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA GLYCOSYLTRANSFERASE; FATTY ACID; MITOCHONDRIAL PROTEIN; OXOGUANINE GLYCOSYLASE 1, HUMAN; SIRT1 PROTEIN, HUMAN; SIRT3 PROTEIN, HUMAN; SIRT4 PROTEIN, HUMAN; SIRT6 PROTEIN, HUMAN; SIRTUIN; SUPEROXIDE DISMUTASE;

ADULT; ALTITUDE; ARTICLE; CLINICAL ARTICLE; CYTOSOL; FATTY ACID METABOLISM; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRION; MOUNTAINEERING; MUSCLE BIOPSY; OXIDATIVE STRESS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; VASTUS LATERALIS MUSCLE; YOUNG ADULT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SKELETAL MUSCLE;

ADULT; ALTITUDE; ANTIGENS, NUCLEAR; DNA GLYCOSYLASES; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FATTY ACIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; MOUNTAINEERING; MUSCLE, SKELETAL; OXIDATIVE STRESS; RNA, MESSENGER; SIRTUIN 1; SIRTUIN 3; SIRTUINS; SUPEROXIDE DISMUTASE;

EID: 84896257334     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2014.02.006     Document Type: Article

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