Is methotrexate administration needed for the treatment of caesarean section scar pregnancy in addition to suction curettage?

European Journal of Contraception and Reproductive Health Care

Volumn 19, Issue 2, 2014, Pages 128-133

  Sevket, Osman ^a,b   Keskin, Seda ^a   Ates, Seda ^a,b   Molla, Taner ^b   Dansuk, Ramazan ^a,b   Yazicioglu, Hasan Fehmi ^a   Yucel, Oguz ^a  

^a Süleymaniye Maternity Training and Research Hospital   (Turkey)

^b BEZMIALEM VAKIF UNIVERSITY   (Turkey)

Author keywords

Caesarean scar pregnancy; Foley catheter; Methotrexate; Suction curettage

Indexed keywords

METHOTREXATE; ABORTIVE AGENT;

ADULT; ARTICLE; CAESAREAN SCAR PREGNANCY; CLINICAL ARTICLE; CURETTAGE; FEMALE; FOLEY BALLOON CATHETER; HUMAN; LENGTH OF STAY; OPERATIVE BLOOD LOSS; PREGNANCY DISORDER; PRIORITY JOURNAL; SURGEON; TREATMENT DURATION; TREATMENT OUTCOME; UTERUS CAVITY; VAGINA BLEEDING; BLADDER CATHETERIZATION; CESAREAN SECTION; CICATRIX; NIDATION; POSTOPERATIVE COMPLICATIONS; PROCEDURES; RETROSPECTIVE STUDY; UTERINE HEMORRHAGE;

ABORTIFACIENT AGENTS, NONSTEROIDAL; ADULT; CESAREAN SECTION; CICATRIX; EMBRYO IMPLANTATION; FEMALE; HUMANS; LENGTH OF STAY; METHOTREXATE; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES; URINARY CATHETERIZATION; UTERINE HEMORRHAGE; VACUUM CURETTAGE;

EID: 84896119424     PISSN: 13625187     EISSN: 14730782     Source Type: Journal    
DOI: 10.3109/13625187.2013.873400     Document Type: Article

References (26)

1. Maymon R, Halperin R, Mendlovic S, et al. Ectopic pregnancies in a Caesarean scar: Review of the medical approach to an iatrogenic complication. Hum Reprod Update 2004; 10: 515-23. (Pubitemid 39529884)
2. Ash A, Smith A, Maxwell D. Caesarean scar pregnancy. BJOG 2007; 114: 253-63.
3. Larsen JV, Solomon MH. Pregnancy in a uterine scar sacculus - an unusual cause of postabortal haemorrhage. A case report. S Afr Med J 1978; 53: 142-3. (Pubitemid 8284318)
4. Jurkovic D, Hillaby K, Woelfer B, et al. First-trimester diagnosis and management of pregnancies implanted into the lower uterine Cesarean section scar. Ultrasound Obstet Gynecol 2003; 21: 220-7. (Pubitemid 36390705)
5. Seow K M, Huang L W, Lin YH, et al. Cesarean scar pregnancy: Issues in management. Ultrasound Obstet Gynecol 2004; 23: 247-53.
6. Leitch C R, Walker J J. The rise in caesarean section rate: the same indications but a lower threshold. Br J Obstet Gynaecol 1998; 105: 621-6. (Pubitemid 28293479)
7. Wang Y-L, Su T-H, Chen H-S. Operative laparoscopy for unruptured ectopic pregnancy in a caesarean scar. BJOG 2006; 113: 1035-8. (Pubitemid 44310095)
8. Herman A, Weinraub Z, Avrech O, et al. Follow-up and outcome of isthmic pregnancy located in a previous caesarean section scar. Br J Obstet Gynaecol 1995; 102: 839-41.
9. Litwicka K, Greco E. Caesarean scar pregnancy: A review of management options. Curr Opin Obstet Gynecol 2011; 23: 415-21.
10. Lian F, Wang Y, Chen W, et al. Uterine artery embolization combined with local methotrexate and systemic methotrexate for treatment of cesarean scar pregnancy with different ultrasonographic pattern. Cardiovasc Intervent Radiol 2012; 35: 286-91.
11. Rotas M, Haberman S, Levgur M. Cesarean scar ectopic pregnancies: Etiology, diagnosis, and management. Obstet Gynecol 2006; 107: 1373-81. (Pubitemid 44336905)
12. Jiang T, Liu G, Huang L, et al. Methotrexate therapy followed by suction curettage followed by Foley tamponade for caesarean scar pregnancy. Eur J Obstet Gynecol Reprod Biol 2011; 156: 209-11.
13. Seow KM, Wang PH, Huang LW, et al. Transvaginal sono-guided aspiration of gestational sac concurrent with a local methotrexate injection for the treatment of unruptured cesarean scar pregnancy. Arch Gynecol Obstet 2013; 288: 361-6.
14. Li N, Zhu F, Fu S, et al. Transvaginal ultrasoundguided embryo aspiration plus local administration of low-dose methotrexate for caesarean scar pregnancy. Ultrasound Med Biol 2012; 38: 209-13.
15. Wang JH, Xu KH, Lin J, et al. Methotrexate therapy for cesarean section scar pregnancy with and without suction curettage. Fertil Steril 2009; 92: 1208-13.
16. Zhuang Y, Huang L. Uterine artery embolization compared with methotrexate for the management of pregnancy implanted within a cesarean scar. Am J Obstet Gynecol 2009; 201: 152.e1-3.
17. Yang XY, Yu H, Li KM, et al. Uterine artery embolisation combined with local methotrexate for treatment of caesarean scar pregnancy. BJOG 2010; 117: 990-6.
18. Zhang X B, Zhong YC, Chi J C, et al. Caesarean scar pregnancy: Treatment with bilateral uterine artery chemoembolization combined with dilation and curettage. J Int Med Res 2012; 40: 1919-30.
19. Shen L, Tan A, Zhu H, et al. Bilateral uterine artery chemoembolization with methotrexate for cesarean scar pregnancy. Am J Obstet Gynecol 2012; 207: 386.e1-6.
20. Li C, Li C, Feng D, et al. Transcatheter arterial chemoembolization versus systemic methotrexate for the management of cesarean scar pregnancy. Int J Gynaecol Obstet 2011; 113: 178-82.
21. Wu X, Zhang X, Zhu J, et al. Caesarean scar pregnancy: Comparative efficacy and safety of treatment by uterine artery chemoembolization and systemic methotrexate injection. Eur J Obstet Gynecol Reprod Biol 2012; 161: 75-9.
22. Wang CJ, Yuen LT, Chao AS, et al. Caesarean scar pregnancy successfully treated by operative hysteroscopy and suction curettage. BJOG 2005; 112: 839-40.
23. Chao A, Wang TH, Wang CJ, et al. Hysteroscopic management of cesarean scar pregnancy after unsuccessful methotrexate treatment. J Minim Invasive Gynecol 2005; 12: 374-6. (Pubitemid 40982547)
24. Lee C L, Wang C J, Chao A, et al. Laparoscopic management of an ectopic pregnancy in a previous Caesarean section scar. Hum Reprod 1999; 14: 1234-6. (Pubitemid 29224898)
25. Wang C J, Chao A S, Yuen L T, et al. Endoscopic management of cesarean scar pregnancy. Fertil Steril 2006; 85: 494:e1 - e4.
26. Bignardi T, Condous G. Transrectal ultrasound-guided surgical evacuation of Cesarean scar ectopic pregnancy. Ultrasound Obstet Gynecol 2010; 35: 481-5.