Singlet oxygen effects on lipid membranes: Implications for the mechanism of action of broad-spectrum viral fusion inhibitors

Biochemical Journal

Volumn 459, Issue 1, 2014, Pages 161-170

  Hollmann, Axel ^a   Castanho, Miguel A R B ^a   Lee, Benhur ^b,c   Santos, Nuno C ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Anisotropy; Fusion inhibition; Generalized polarization; HIV 1; Membrane fusion; Singlet oxygen

Indexed keywords

9,10 DIMETHYLANTHRACENE; ANTHRACENE DERIVATIVE; ANTIVIRUS AGENT; JL 103; LIPID; LJ 001; LJ 025; OXAZOLIDINE 2,4 DITHIONE; OXAZOLIDINE DERIVATIVE; SINGLET OXYGEN; UNCLASSIFIED DRUG; VIRAL FUSION INHIBITOR;

ANIMAL CELL; ANISOTROPY; ARTICLE; CELL MEMBRANE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENCE SPECTROSCOPY; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE FLUIDITY; MEMBRANE FUSION; MEMBRANE MODEL; MOLECULE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; QUANTUM YIELD; VIRUS ENTRY; VIRUS ENVELOPE;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CELL MEMBRANE; HIV ENVELOPE PROTEIN GP41; MEMBRANE LIPIDS; MOLECULAR SEQUENCE DATA; RHODANINE; SINGLET OXYGEN; VIRAL FUSION PROTEINS;

EID: 84896119125     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20131058     Document Type: Article

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