Compassionate use of vismodegib and adjuvant radiotherapy in the treatment of multiple locally advanced and inoperable basal cell carcinomas and squamous cell carcinomas of the skin

Journal of the American Academy of Dermatology

Volumn 70, Issue 4, 2014, Pages

  Gathings, Robert M ^a   Orscheln, Courtney S ^a   Huang, William W ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VISMODEGIB;

ADVANCED CANCER; AGED; BASAL CELL CARCINOMA; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CASE REPORT; COMPASSIONATE USE; DISEASE SEVERITY; ECTROPION; FACE INJURY; FOLLOW UP; HUMAN; LETTER; MALE; PRIORITY JOURNAL; RADIATION DOSE; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME; TREATMENT RESPONSE; VERY ELDERLY;

AGED, 80 AND OVER; ANILIDES; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; COMPASSIONATE USE TRIALS; FACE; FOLLOW-UP STUDIES; HUMANS; MALE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PYRIDINES; RADIOTHERAPY, ADJUVANT; RISK ASSESSMENT; SKIN NEOPLASMS; TERMINALLY ILL; TREATMENT OUTCOME;

EID: 84896098061     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2013.11.032     Document Type: Article

References (3)

1. Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med 2012;366:2171-9.
2. Chang AL, Oro AE. Initial assessment of tumor regrowth after vismodegib in advanced basal call carcinoma. Arch Dermatol 2012;148:1324-5.
3. Iarrobino A, Messina JL, Kudchadkar R, Sondak VK. Emergence of a squamous cell carcinoma phenotype following treatment of metastatic basal cell carcinoma with vismodegib. J Am Acad Dermatol 2013;69:e33-4.