Pharmacokinetics of liposomal-encapsulated and un-encapsulated vincristine after injection of liposomal vincristine sulfate in beagle dogs

Cancer Chemotherapy and Pharmacology

Volumn 73, Issue 3, 2014, Pages 459-466

  Zhong, Jie ^a   Mao, Wenxue ^b   Shi, Rong ^a   Jiang, Peng ^a   Wang, Qian ^a   Zhu, Rong ^a   Wang, Tianming ^a   Ma, Yueming ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai Fudan Zhangjiang Bio pharmaceutical Co Ltd   (China)

Author keywords

LC MS MS; Liposomal encapsulated drug; Pharmacokinetics; Solid phase extraction; Un encapsulated drug; Vincristine sulfate

Indexed keywords

VINCRISTINE SULFATE;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BEAGLE; COMPARTMENT MODEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG DISTRIBUTION; DRUG HALF LIFE; ENCAPSULATION; FEMALE; LIPOSOMAL DELIVERY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHROMATOGRAPHY, LIQUID; DISEASE MODELS, ANIMAL; DOGS; FEMALE; INJECTIONS, INTRAVENOUS; LIPOSOMES; MALE; RANDOM ALLOCATION; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VINCRISTINE;

EID: 84896049526     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-013-2369-5     Document Type: Article

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